Analysis of the Tunicamycin Biosynthetic Gene Cluster of Streptomyces chartreusis Reveals New Insights into Tunicamycin Production and Immunity

por Widdick, David, Royer, Sylvain F., Wang, Hua, Vior, Natalia M., Gomez-Escribano, Juan Pablo, Davis, Benjamin G., Bibb, Mervyn J.
Publicado 2018

Structurally Informed Mutagenesis of a Stereochemically Promiscuous Aldolase Produces Mutants That Catalyze the Diastereoselective Syntheses of All Four Stereoisomers of 3-Deoxy-he...

por Royer, Sylvain F., Gao, Xuan, Groleau, Robin R., van der Kamp, Marc W., Bull, Steven D., Danson, Michael J., Crennell, Susan J.
Publicado 2022

Structures of DPAGT1 Explain Glycosylation Disease Mechanisms and Advance TB Antibiotic Design

por Dong, Yin Yao, Wang, Hua, Pike, Ashley C.W., Cochrane, Stephen A., Hamedzadeh, Sadra, Wyszyński, Filip J., Bushell, Simon R., Royer, Sylvain F., Widdick, David A., Sajid, Andaleeb, Boshoff, Helena I., Park, Yumi, Lucas, Ricardo, Liu, Wei-Min, Lee, Seung Seo, Machida, Takuya, Minall, Leanne, Mehmood, Shahid, Belaya, Katsiaryna, Liu, Wei-Wei, Chu, Amy, Shrestha, Leela, Mukhopadhyay, Shubhashish M.M., Strain-Damerell, Claire, Chalk, Rod, Burgess-Brown, Nicola A., Bibb, Mervyn J., Barry III, Clifton E., Robinson, Carol V., Beeson, David, Davis, Benjamin G., Carpenter, Elisabeth P.
Publicado 2018