Toward clinical understanding of aristolochic acid upper-tract urothelial carcinoma

por Boot, Arnoud, Jiang, Nanhai, Rozen, Steven G.
Publicado 2020

mSigHdp: hierarchical Dirichlet process mixture modeling for mutational signature discovery

por Liu, Mo, Wu, Yang, Jiang, Nanhai, Boot, Arnoud, Rozen, Steven G
Publicado 2023

Mutational processes in cancer preferentially affect binding of particular transcription factors

por Liu, Mo, Boot, Arnoud, Ng, Alvin W. T., Gordân, Raluca, Rozen, Steven G.
Publicado 2021

Evaluation and optimisation of indel detection workflows for ion torrent sequencing of the BRCA1 and BRCA2 genes

por Yeo, Zhen Xuan, Wong, Joshua Chee Leong, Rozen, Steven G, Lee, Ann Siew Gek
Publicado 2014

Mutation signatures of carcinogen exposure: genome-wide detection and new opportunities for cancer prevention

por Poon, Song Ling, McPherson, John R, Tan, Patrick, Teh, Bin Tean, Rozen, Steven G
Publicado 2014

Differentially Expressed miRNAs in Hepatocellular Carcinoma Target Genes in the Genetic Information Processing and Metabolism Pathways

por Thurnherr, Thomas, Mah, Way-Champ, Lei, Zhengdeng, Jin, Yu, Rozen, Steven G., Lee, Caroline G.
Publicado 2016

Accuracy of mutational signature software on correlated signatures

por Wu, Yang, Chua, Ellora Hui Zhen, Ng, Alvin Wei Tian, Boot, Arnoud, Rozen, Steven G.
Publicado 2022

Primer3—new capabilities and interfaces

por Untergasser, Andreas, Cutcutache, Ioana, Koressaar, Triinu, Ye, Jian, Faircloth, Brant C., Remm, Maido, Rozen, Steven G.
Publicado 2012

MSIseq: Software for Assessing Microsatellite Instability from Catalogs of Somatic Mutations

por Ni Huang, Mi, McPherson, John R., Cutcutache, Ioana, Teh, Bin Tean, Tan, Patrick, Rozen, Steven G.
Publicado 2015

SigProfilerMatrixGenerator: a tool for visualizing and exploring patterns of small mutational events

por Bergstrom, Erik N., Huang, Mi Ni, Mahto, Uma, Barnes, Mark, Stratton, Michael R., Rozen, Steven G., Alexandrov, Ludmil B.
Publicado 2019

The NF1 gene revisited – from bench to bedside

por Yap, Yoon-Sim, McPherson, John R, Ong, Choon-Kiat, Rozen, Steven G, Teh, Bin-Tean, Lee, Ann SG, Callen, David F
Publicado 2014

Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers

por Boot, Arnoud, Liu, Mo, Stantial, Nicole, Shah, Viraj, Yu, Willie, Nitiss, Karin C., Nitiss, John L., Jinks-Robertson, Sue, Rozen, Steven G.
Publicado 2022

A tumor-associated splice-isoform of MAP2K7 drives dedifferentiation in MBNL1-low cancers via JNK activation

por Ray, Debleena, Yun, Yu Chye, Idris, Muhammad, Cheng, Shanshan, Boot, Arnoud, Iain, Tan Bee Huat, Rozen, Steven G., Tan, Patrick, Epstein, David M.
Publicado 2020

Characterization of colibactin-associated mutational signature in an Asian oral squamous cell carcinoma and in other mucosal tumor types

por Boot, Arnoud, Ng, Alvin W.T., Chong, Fui Teen, Ho, Szu-Chi, Yu, Willie, Tan, Daniel S.W., Iyer, N. Gopalakrishna, Rozen, Steven G.
Publicado 2020

Enhancer-derived long non-coding RNAs CCAT1 and CCAT2 at rs6983267 has limited predictability for early stage colorectal carcinoma metastasis

por Thean, Lai Fun, Blöcker, Christopher, Li, Hui Hua, Lo, Michelle, Wong, Michelle, Tang, Choong Leong, Tan, Emile K. W., Rozen, Steven G., Cheah, Peh Yean
Publicado 2021

In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors

por Boot, Arnoud, Huang, Mi Ni, Ng, Alvin W.T., Ho, Szu-Chi, Lim, Jing Quan, Kawakami, Yoshiiku, Chayama, Kazuaki, Teh, Bin Tean, Nakagawa, Hidewaki, Rozen, Steven G.
Publicado 2018

Inherited breast cancer predisposition in Asians: multigene panel testing outcomes from Singapore

por Wong, Edward S Y, Shekar, Sandhya, Met-Domestici, Marie, Chan, Claire, Sze, Melody, Yap, Yoon Sim, Rozen, Steven G, Tan, Min-Han, Ang, Peter, Ngeow, Joanne, Lee, Ann S G
Publicado 2016

Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer

por Tang, Yew Chung, Ho, Szu-Chi, Tan, Elisabeth, Ng, Alvin Wei Tian, McPherson, John R., Goh, Germaine Yen Lin, Teh, Bin Tean, Bard, Frederic, Rozen, Steven G.
Publicado 2018

Abundant copy-number loss of CYCLOPS and STOP genes in gastric adenocarcinoma

por Cutcutache, Ioana, Wu, Alice Yingting, Suzuki, Yuka, McPherson, John Richard, Lei, Zhengdeng, Deng, Niantao, Zhang, Shenli, Wong, Wai Keong, Soo, Khee Chee, Chan, Weng Hoong, Ooi, London Lucien, Welsch, Roy, Tan, Patrick, Rozen, Steven G.
Publicado 2015

Digital phenotyping by consumer wearables identifies sleep-associated markers of cardiovascular disease risk and biological aging

por Teo, Jing Xian, Davila, Sonia, Yang, Chengxi, Hii, An An, Pua, Chee Jian, Yap, Jonathan, Tan, Swee Yaw, Sahlén, Anders, Chin, Calvin Woon-Loong, Teh, Bin Tean, Rozen, Steven G., Cook, Stuart Alexander, Yeo, Khung Keong, Tan, Patrick, Lim, Weng Khong
Publicado 2019