A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptor

por Ruan, Cheng-Huai, Wu, Jaixin, Ruan, Ke-He
Publicado 2005

Process of Fragment-Based Lead Discovery—A Perspective from NMR

por Ma, Rongsheng, Wang, Pengchao, Wu, Jihui, Ruan, Ke
Publicado 2016

An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E(2 )or E(1 )activity through subtype EP(1 )receptor: Suitabl...

por Chillar, Annirudha J, Karimi, Parastoo, Tang, Kathy, Ruan, Ke-He
Publicado 2011

A novel single‐chain enzyme complex with chain reaction properties rapidly producing thromboxane A(2) and exhibiting powerful anti‐bleeding functions

por Li, Yan, Li, Qun‐Ying, Ling, Qing‐Lan, So, Shui‐Ping, Ruan, Ke‐He
Publicado 2019

Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation

por Lin, Xiao, Wang, Zhuo-Jun, Huang, Fang, Liang, Shuang, Shen, Lan, Feng, Yi, Ruan, Ke-Feng
Publicado 2011

Automated NMR Fragment Based Screening Identified a Novel Interface Blocker to the LARG/RhoA Complex

por Gao, Jia, Ma, Rongsheng, Wang, Wei, Wang, Na, Sasaki, Ryan, Snyderman, David, Wu, Jihui, Ruan, Ke
Publicado 2014

Creating a mouse model resistant to induced ischemic stroke and cardiovascular damage

por Ling, Qing-Lan, Mohite, Anita J., Murdoch, Emma, Akasaka, Hironari, Li, Qun-Ying, So, Shui-Ping, Ruan, Ke-He
Publicado 2018

Driving force of biomolecular liquid–liquid phase separation probed by nuclear magnetic resonance spectroscopy

por Zhang, Hanyu, Fan, Weiwei, Nshogoza, Gilbert, Liu, Yaqian, Gao, Jia, Wu, Jihui, Shi, Yunyu, Tu, Xiaoming, Zhang, Jiahai, Ruan, Ke
Publicado 2022

Zhujie Hewei Granules Ameliorated Reflux Esophagitis in Rats

por Qiu, Yue, Hu, Jia-liang, Zhao, Chun-cao, Zhang, Ji-quan, Wu, Fei, Ma, Bing-liang, Feng, Yi, Ruan, Ke-feng
Publicado 2019

NMR Fragment-Based Screening against Tandem RNA Recognition Motifs of TDP-43

por Nshogoza, Gilbert, Liu, Yaqian, Gao, Jia, Liu, Mingqing, Moududee, Sayed Ala, Ma, Rongsheng, Li, Fudong, Zhang, Jiahai, Wu, Jihui, Shi, Yunyu, Ruan, Ke
Publicado 2019

Fragment-Based Discovery of AF9 YEATS Domain Inhibitors

por Liu, Yaqian, Jin, Ruoxing, Lu, Hui, Bian, Kangjie, Wang, Rui, Wang, Lei, Gao, Rui, Zhang, Jiahai, Wu, Jihui, Yao, Xuebiao, Liu, Xing, Liu, Dan, Wang, Xisheng, Zhang, Zhiyong, Ruan, Ke
Publicado 2022

Inhibitors against Two PDZ Domains of MDA-9 Suppressed Migration of Breast Cancer Cells

por Tang, Heng, Wang, Lei, Li, Shuju, Wei, Xiaoli, Lv, Mengqi, Zhong, Fumei, Liu, Yaqian, Liu, Jiuyang, Fu, Bangguo, Zhu, Qizhi, Wang, Dan, Liu, Jiajia, Ruan, Ke, Gao, Jia, Xu, Weiping
Publicado 2023

Aurora A–mediated pyruvate kinase M2 phosphorylation promotes biosynthesis with glycolytic metabolites and tumor cell cycle progression

por Jiang, Ya, Wang, Ting, Sheng, Dandan, Han, Chaoqiang, Xu, Tian, Zhang, Peng, You, Weiyi, Fan, Weiwei, Zhang, Zhiyong, Jin, Tengchuan, Duan, Xiaotao, Yuan, Xiao, Liu, Xing, Zhang, Kaiguang, Ruan, Ke, Shi, Jue, Guo, Jing, Cheng, Aoxing, Yang, Zhenye
Publicado 2022

Mitosis-specific acetylation tunes Ran effector binding for chromosome segregation

por Bao, Xiaoling, Liu, Heng, Liu, Xing, Ruan, Ke, Zhang, Yonghui, Zhang, Zhiyong, Hu, Qi, Liu, Ying, Akram, Saima, Zhang, Jiahai, Gong, Qingguo, Wang, Wenwen, Yuan, Xiao, Li, Jian, Zhao, Lingli, Dou, Zhen, Tian, Ruijun, Yao, Xuebiao, Wu, Jihui, Shi, Yunyu
Publicado 2017

Mitotic motor CENP-E cooperates with PRC1 in temporal control of central spindle assembly

por Liu, Xu, Xu, Leilei, Li, Junying, Yao, Phil Y, Wang, Wanjuan, Ismail, Hazrat, Wang, Haowei, Liao, Bryce, Yang, Zhihong, Ward, Tarsha, Ruan, Ke, Zhang, Jianchun, Wu, Quan, He, Ping, Ding, Xia, Wang, Dongmei, Fu, Chuanhai, Dou, Zhen, Yan, Feng, Wang, Wenwen, Liu, Xing, Yao, Xuebiao
Publicado 2019

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl (1)H-NMR probe

por Liu, Qi, He, Qing-tao, Lyu, Xiaoxuan, Yang, Fan, Zhu, Zhong-liang, Xiao, Peng, Yang, Zhao, Zhang, Feng, Yang, Zhao-ya, Wang, Xiao-yan, Sun, Peng, Wang, Qian-wen, Qu, Chang-xiu, Gong, Zheng, Lin, Jing-yu, Xu, Zhen, Song, Shao-le, Huang, Shen-ming, Guo, Sheng-chao, Han, Ming-jie, Zhu, Kong-kai, Chen, Xin, Kahsai, Alem W., Xiao, Kun-Hong, Kong, Wei, Li, Fa-hui, Ruan, Ke, Li, Zi-jian, Yu, Xiao, Niu, Xiao-gang, Jin, Chang-wen, Wang, Jiangyun, Sun, Jin-peng
Publicado 2020