Proteostasis Dysfunction in Aged Mammalian Cells. The Stressful Role of Inflammation

por Ruano, Diego
Publicado 2021

Neuroinflammation alters cellular proteostasis by producing endoplasmic reticulum stress, autophagy activation and disrupting ERAD activation

por Pintado, Cristina, Macías, Sandra, Domínguez-Martín, Helena, Castaño, Angélica, Ruano, Diego
Publicado 2017

Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism

por Gavilán, Elena, Giráldez, Servando, Sánchez-Aguayo, Inmaculada, Romero, Francisco, Ruano, Diego, Daza, Paula
Publicado 2015

SIRT1 activation with neuroheal is neuroprotective but SIRT2 inhibition with AK7 is detrimental for disconnected motoneurons

por Romeo-Guitart, David, Leiva-Rodríguez, Tatiana, Espinosa-Alcantud, María, Sima, Núria, Vaquero, Alejandro, Domínguez- Martín, Helena, Ruano, Diego, Casas, Caty
Publicado 2018

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition...

por Pintado, Cristina, Gavilán, María P, Gavilán, Elena, García-Cuervo, Luisa, Gutiérrez, Antonia, Vitorica, Javier, Castaño, Angélica, Ríos, Rosa M, Ruano, Diego
Publicado 2012

Learning improvement after PI3K activation correlates with de novo formation of functional small spines

por Enriquez-Barreto, Lilian, Cuesto, Germán, Dominguez-Iturza, Nuria, Gavilán, Elena, Ruano, Diego, Sandi, Carmen, Fernández-Ruiz, Antonio, Martín-Vázquez, Gonzalo, Herreras, Oscar, Morales, Miguel
Publicado 2014

Abnormal accumulation of autophagic vesicles correlates with axonal and synaptic pathology in young Alzheimer’s mice hippocampus

por Sanchez-Varo, Raquel, Trujillo-Estrada, Laura, Sanchez-Mejias, Elisabeth, Torres, Manuel, Baglietto-Vargas, David, Moreno-Gonzalez, Ines, De Castro, Vanessa, Jimenez, Sebastian, Ruano, Diego, Vizuete, Marisa, Davila, Jose Carlos, Garcia-Verdugo, Jose Manuel, Jimenez, Antonio Jesus, Vitorica, Javier, Gutierrez, Antonia
Publicado 2011

Autophagic receptor p62 protects against glycation‐derived toxicity and enhances viability

por Aragonès, Gemma, Dasuri, Kalavathi, Olukorede, Opeoluwa, Francisco, Sarah G., Renneburg, Carol, Kumsta, Caroline, Hansen, Malene, Kageyama, Shun, Komatsu, Masaaki, Rowan, Sheldon, Volkin, Jonathan, Workman, Michael, Yang, Wenxin, Daza, Paula, Ruano, Diego, Dominguez‐Martín, Helena, Rodríguez‐Navarro, José Antonio, Du, Xue‐Liang, Brownlee, Michael A., Bejarano, Eloy, Taylor, Allen
Publicado 2020