Young systemic factors as a medicine for age-related neurodegenerative diseases

por Katsimpardi, Lida, Rubin, Lee L
Publicado 2015

Stem cell biology and drug discovery

por Rubin, Lee L, Haston, Kelly M
Publicado 2011

Suppression of MAP4K4 Signaling Ameliorates Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis-Molecular Studies Toward New Therapeutics

por Watts, Michelle E, Wu, Chen, Rubin, Lee L
Publicado 2019

Blocking Cytochrome c Activity within Intact Neurons Inhibits Apoptosis

por Neame, Stephen J., Rubin, Lee L., Philpott, Karen L.
Publicado 1998

GDF11 expressed in the adult brain negatively regulates hippocampal neurogenesis

por Mayweather, Brittany A., Buchanan, Sean M., Rubin, Lee L.
Publicado 2021

Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice

por Ozek, Ceren, Krolewski, Richard C., Buchanan, Sean M., Rubin, Lee L.
Publicado 2018

Activated Phosphatidylinositol 3-Kinase and Akt Kinase Promote Survival of Superior Cervical Neurons

por Philpott, Karen L., McCarthy, Mary Jane, Klippel, Anke, Rubin, Lee L.
Publicado 1997

Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture

por Paik, Elizabeth J., O’Neil, Alison L., Ng, Shi-Yan, Sun, Chicheng, Rubin, Lee L.
Publicado 2018

Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryoni...

por Sadegh, Cameron, Ebina, Wataru, Arvanites, Anthony C., Davidow, Lance S., Rubin, Lee L., Macklis, Jeffrey D.
Publicado 2021

Aggregated SOD1 causes selective death of cultured human motor neurons

por Benkler, Chen, O’Neil, Alison L., Slepian, Susannah, Qian, Fang, Weinreb, Paul H., Rubin, Lee L.
Publicado 2018

Growth differentiation factor 11 (GDF11) has pronounced effects on skin biology

por Idkowiak-Baldys, Jolanta, Santhanam, Uma, Buchanan, Sean M., Pfaff, Kathleen Lindahl, Rubin, Lee L., Lyga, John
Publicado 2019

Implementation of a Drug Screening Platform to TargetGch1 Expression in Injured Mouse Dorsal Root Ganglion Neurons

por Cronin, Shane J. F., Davidow, Lance S., Arvanites, Anthony C., Rubin, Lee L., Penninger, Josef M., Woolf, Clifford J.
Publicado 2023

Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imaging

por Tomov, Martin L., O’Neil, Alison, Abbasi, Hamdah S., Cimini, Beth A., Carpenter, Anne E., Rubin, Lee L., Bathe, Mark
Publicado 2021

Using Automated Live Cell Imaging to Reveal Early Changes during Human Motor Neuron Degeneration

por Shin, Hye Young, Pfaff, Kathleen L., Davidow, Lance S., Sun, Chicheng, Uozumi, Takayuki, Yanagawa, Fumiki, Yamazaki, Yoichi, Kiyota, Yasujiro, Rubin, Lee L.
Publicado 2018

A neuroprotective agent that inactivates prodegenerative TrkA and preserves mitochondria

por Feinberg, Konstantin, Kolaj, Adelaida, Wu, Chen, Grinshtein, Natalie, Krieger, Jonathan R., Moran, Michael F., Rubin, Lee L., Miller, Freda D., Kaplan, David R.
Publicado 2017

Systemic nature of spinal muscular atrophy revealed by studying insurance claims

por Lipnick, Scott L., Agniel, Denis M., Aggarwal, Rahul, Makhortova, Nina R., Finlayson, Samuel G., Brocato, Alexandra, Palmer, Nathan, Darras, Basil T., Kohane, Isaac, Rubin, Lee L.
Publicado 2019

Reversal of β cell de-differentiation by a small molecule inhibitor of the TGFβ pathway

por Blum, Barak, Roose, Adam N, Barrandon, Ornella, Maehr, René, Arvanites, Anthony C, Davidow, Lance S, Davis, Jeffrey C, Peterson, Quinn P, Rubin, Lee L, Melton, Douglas A
Publicado 2014

Pro-myogenic small molecules revealed by a chemical screen on primary muscle stem cells

por Buchanan, Sean M., Price, Feodor D., Castiglioni, Alessandra, Gee, Amanda Wagner, Schneider, Joel, Matyas, Mark N., Hayhurst, Monica, Tabebordbar, Mohammadsharif, Wagers, Amy J., Rubin, Lee L.
Publicado 2020

Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy

por Walsh, Melissa B., Janzen, Eva, Wingrove, Emily, Hosseinibarkooie, Seyyedmohsen, Muela, Natalia Rodriguez, Davidow, Lance, Dimitriadi, Maria, Norabuena, Erika M., Rubin, Lee L., Wirth, Brunhilde, Hart, Anne C.
Publicado 2020

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

por Frank-Kamenetsky, Maria, Zhang, Xiaoyan M, Bottega, Steve, Guicherit, Oivin, Wichterle, Hynek, Dudek, Henryk, Bumcrot, David, Wang, Frank Y, Jones, Simon, Shulok, Janine, Rubin, Lee L, Porter, Jeffery A
Publicado 2002