727. Potency of the β-Lactamase Inhibitor QPX7728 Is Minimally Affected by KPC Mutations that Reduce Potency of Ceftazidime–Avibactam

por Lomovskaya, Olga, Nelson, Kirk J, Rubio-Aparicio, Debora
Publicado 2019

The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterob...

por Lomovskaya, Olga, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Loutit, Jeff, Dudley, Michael
Publicado 2022

Meropenem-Vaborbactam Resistance Selection, Resistance Prevention, and Molecular Mechanisms in Mutants of KPC-Producing Klebsiella pneumoniae

por Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Dudley, Michael N., Lomovskaya, Olga
Publicado 2017

681. In vitro Activity of the β-Lactamase Inhibitor QPX7728 in Combination with Several β-Lactams Against Acinetobacter baumannii (AB) and Pseudomonas aeruginosa (PSA)

por Lomovskaya, Olga, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk J, Castanheira, Mariana
Publicado 2019

Impact of Intrinsic Resistance Mechanisms on Potency of QPX7728, a New Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases in Enterobacteriaceae, Pse...

por Lomovskaya, Olga, Nelson, Kirk, Rubio-Aparicio, Debora, Tsivkovski, Ruslan, Sun, Dongxu, Dudley, Michael N.
Publicado 2020

Intrinsic Antibacterial Activity of Xeruborbactam In Vitro: Assessing Spectrum and Mode of Action

por Sun, Dongxu, Tsivkovski, Ruslan, Pogliano, Joe, Tsunemoto, Hannah, Nelson, Kirk, Rubio-Aparicio, Debora, Lomovskaya, Olga
Publicado 2022

Spectrum of Beta-Lactamase Inhibition by the Cyclic Boronate QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor of Serine and Metallo-Beta-Lactamases: Enhancement of Activity...

por Lomovskaya, Olga, Tsivkovski, Ruslan, Nelson, Kirk, Rubio-Aparicio, Debora, Sun, Dongxu, Totrov, Maxim, Dudley, Michael N.
Publicado 2020

Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae

por Lomovskaya, Olga, Sun, Dongxu, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Griffith, David C., Dudley, Michael N.
Publicado 2017

In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa

por Lomovskaya, Olga, Rubio-Aparicio, Debora, Nelson, Kirk, Sun, Dongxu, Tsivkovski, Ruslan, Castanheira, Mariana, Lindley, Jill, Loutit, Jeffery, Dudley, Michael
Publicado 2021

In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-re...

por Lomovskaya, Olga, Castanheira, Mariana, Lindley, Jill, Rubio-Aparicio, Debora, Nelson, Kirk, Tsivkovski, Ruslan, Sun, Dongxu, Totrov, Maxim, Loutit, Jeffery, Dudley, Michael
Publicado 2023