Enteropathogenic Escherichia coli (EPEC) inactivate innate immune responses prior to compromising epithelial barrier function

por Ruchaud-Sparagano, Marie-Hélène, Maresca, Marc, Kenny, Brendan
Publicado 2007

Proteasome-independent Degradation of Canonical NFκB Complex Components by the NleC Protein of Pathogenic Escherichia coli

por Mühlen, Sabrina, Ruchaud-Sparagano, Marie-Hélène, Kenny, Brendan
Publicado 2011

The Enteropathogenic E. coli (EPEC) Tir Effector Inhibits NF-κB Activity by Targeting TNFα Receptor-Associated Factors

por Ruchaud-Sparagano, Marie-Hélène, Mühlen, Sabrina, Dean, Paul, Kenny, Brendan
Publicado 2011

Src kinase inhibition with dasatinib impairs neutrophil function and clearance of Escherichia coli infection in a murine model of acute lung injury

por Macfarlane, James G., Dorward, David A., Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Lucas, Christopher D., Rossi, Adriano G., Simpson, A. John
Publicado 2020

Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ

por Widdrington, John D., Gomez-Duran, Aurora, Steyn, Jannetta S., Pyle, Angela, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Baudouin, Simon V., Rostron, Anthony J., Simpson, John, Chinnery, Patrick F.
Publicado 2017

Exposure of Monocytic Cells to Lipopolysaccharide Induces Coordinated Endotoxin Tolerance, Mitochondrial Biogenesis, Mitophagy, and Antioxidant Defenses

por Widdrington, John D., Gomez-Duran, Aurora, Pyle, Angela, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Baudouin, Simon V., Rostron, Anthony J., Lovat, Penny E., Chinnery, Patrick F., Simpson, A. John
Publicado 2018

Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace

por Jardine, Laura, Wiscombe, Sarah, Reynolds, Gary, McDonald, David, Fuller, Andrew, Green, Kile, Filby, Andrew, Forrest, Ian, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Collin, Matthew, Haniffa, Muzlifah, Simpson, A. John
Publicado 2019

C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling

por Wood, Alexander J.T., Vassallo, Arlette M., Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Zinnato, Carmelo, Gonzalez-Tejedo, Carmen, Kishore, Kamal, D’Santos, Clive S., Simpson, A. John, Menon, David K., Summers, Charlotte, Chilvers, Edwin R., Okkenhaug, Klaus, Morris, Andrew Conway
Publicado 2020

A human model of bilateral pulmonary vein sampling to assess the effects of one-lung ventilation on neutrophil function

por Funston, Wendy, Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Powell, Jason, Cooles, Faye A. H., Shelmerdine, Lauren, McDowell, Cliona, O’Leary, Denis, Booth, Karen L., Clark, Stephen C., Ledingham, Simon J., Rostron, Anthony J., Dark, John H., Simpson, A. John
Publicado 2022

Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis

por Pinder, Emma M, Rostron, Anthony J, Hellyer, Thomas P, Ruchaud-Sparagano, Marie-Helene, Scott, Jonathan, Macfarlane, James G, Wiscombe, Sarah, Widdrington, John D, Roy, Alistair I, Linnett, Vanessa C, Baudouin, Simon V, Wright, Stephen E, Chadwick, Thomas, Fouweather, Tony, Juss, Jatinder K, Chilvers, Edwin R, Bowett, Susan A, Parker, Jennie, McAuley, Daniel F, Conway Morris, Andrew, Simpson, A John
Publicado 2018

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia

por Hellyer, Thomas P, Conway Morris, Andrew, McAuley, Daniel F, Walsh, Timothy S, Anderson, Niall H, Singh, Suveer, Dark, Paul, Roy, Alistair I, Baudouin, Simon V, Wright, Stephen E, Perkins, Gavin D, Kefala, Kallirroi, Jeffels, Melinda, McMullan, Ronan, O'Kane, Cecilia M, Spencer, Craig, Laha, Shondipon, Robin, Nicole, Gossain, Savita, Gould, Kate, Ruchaud-Sparagano, Marie-Hélène, Scott, Jonathan, Browne, Emma M, MacFarlane, James G, Wiscombe, Sarah, Widdrington, John D, Dimmick, Ian, Laurenson, Ian F, Nauwelaers, Frans, Simpson, A John
Publicado 2014

Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner

por Lagnado, Anthony, Leslie, Jack, Ruchaud‐Sparagano, Marie‐Helene, Victorelli, Stella, Hirsova, Petra, Ogrodnik, Mikolaj, Collins, Amy L, Vizioli, Maria Grazia, Habiballa, Leena, Saretzki, Gabriele, Evans, Shane A, Salmonowicz, Hanna, Hruby, Adam, Geh, Daniel, Pavelko, Kevin D, Dolan, David, Reeves, Helen L, Grellscheid, Sushma, Wilson, Colin H, Pandanaboyana, Sanjay, Doolittle, Madison, von Zglinicki, Thomas, Oakley, Fiona, Gallage, Suchira, Wilson, Caroline L, Birch, Jodie, Carroll, Bernadette, Chapman, James, Heikenwalder, Mathias, Neretti, Nicola, Khosla, Sundeep, Masuda, Claudio Akio, Tchkonia, Tamar, Kirkland, James L, Jurk, Diana, Mann, Derek A, Passos, João F
Publicado 2021