Glutamate carboxypeptidase activity in human skin biopsies as a pharmacodynamic marker for clinical studies

por Rojas, Camilo, Stathis, Marigo, Polydefkis, Michael, Rudek, Michelle A, Zhao, Ming, Ebenezer, Gigi J, Slusher, Barbara S
Publicado 2011

Nelfinavir Inhibition of Kaposi’s sarcoma-associated herpesvirus protein expression and capsid assembly

por Li, Maggie, Smith, Barbara, Jaeyeun, Lee, Petr, Jennifer, Wiseman, Robyn, Anders, Nicole, Rudek, Michelle, Ambinder, Richard, Desai, Prashant
Publicado 2023

A Novel 2-Carbon-Linked Dimeric Artemisinin With Potent Antileukemic Activity and Favorable Pharmacology

por Kagan, Amanda B., Moses, Blake S., Mott, Bryan T., Rai, Ganesha, Anders, Nicole M., Rudek, Michelle A., Civin, Curt I.
Publicado 2022

DNA methyltransferase inhibitor exposure–response: Challenges and opportunities

por Kagan, Amanda B., Garrison, Dominique A., Anders, Nicole M., Webster, Jonathan A., Baker, Sharyn D., Yegnasubramanian, Srinivasan, Rudek, Michelle A.
Publicado 2023

Exploring pharmacokinetics of talazoparib in ABCB1/ABCG2-deficient mice using a novel UHPLC-MS/MS method

por Talebi, Zahra, Garrison, Dominique A., Eisenmann, Eric D., Parmar, Kalindi, Shapiro, Geoffrey I., Rudek, Michelle A., Sparreboom, Alex, Jin, Yan
Publicado 2023

Clonidine for sedation in infants during therapeutic hypothermia with neonatal encephalopathy: pilot study

por Gauda, Estelle B, Chavez-Valdez, Raul, Northington, Frances J, Lee, Carlton KK, Rudek, Michelle A, Guglieri-Lopez, Beatriz, Ivaturi, Vijay
Publicado 2022

Pharmacodynamic study of Disulfiram in Men with Non-metastatic Recurrent Prostate Cancer

por Schweizer, Michael T., Lin, Jianqing, Blackford, Amanda, Bardia, Aditya, King, Serina, Armstrong, Andrew J., Rudek, Michelle A., Yegnasubramanian, Srinivasan, Carducci, Michael A.
Publicado 2013

Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure‐FLT3 Relationship

por Liu, Tao, Ivaturi, Vijay, Sabato, Philip, Gobburu, Jogarao V. S., Greer, Jacqueline M., Wright, John J., Smith, B. Douglas, Pratz, Keith W., Rudek, Michelle A.
Publicado 2018

Safety and Tolerability of Carboplatin and Paclitaxel in Cancer Patients with HIV (AMC-078), an AIDS Malignancy Consortium (AMC) Study

por Haigentz, Missak, Moore, Page, Bimali, Milan, Cooley, Timothy, Sparano, Joseph, Rudek, Michelle, Ratner, Lee, Henry, David, Ramos, Juan, Deeken, John, Rubinstein, Paul, Chiao, Elizabeth
Publicado 2022

Phase 1 Study of ABT‐751 in Combination With CAPIRI (Capecitabine and Irinotecan) and Bevacizumab in Patients With Advanced Colorectal Cancer

por Rudek, Michelle A., Dasari, Arvind, Laheru, Daniel, He, Ping, Jin, Runyan, Walker, Rosalind, Taylor, Gretchen E., Jimeno, Antonio, Donehower, Ross C., Hidalgo, Manuel, Messersmith, Wells A., Purcell, W. Thomas
Publicado 2016

Exosome-Encased Nucleic Acid Scaffold Chemotherapeutic Agents for Superior Anti-Tumor and Anti-Angiogenesis Activity

por McNamara, Ryan P., Eason, Anthony B., Zhou, Yijun, Bigi, Rachele, Griffith, Jack D., Costantini, Lindsey M., Rudek, Michelle A., Anders, Nicole M., Damania, Blossom A., Dittmer, Dirk P.
Publicado 2022

Development and anticancer properties of Up284, a spirocyclic candidate ADRM1/RPN13 inhibitor

por Anchoori, Ravi K., Anchoori, Vidyasagar, Lam, Brandon, Tseng, Ssu-Hsueh, Das, Samarjit, Velasquez, Fernanda Carrizo, Karanam, Balasubramanyam, Poddatoori, Deepika, Patnam, Ramesh, Rudek, Michelle A., Chang, Yung-Nien, Roden, Richard B. S.
Publicado 2023

Shorter-course treatment for Mycobacterium ulcerans disease with high-dose rifamycins and clofazimine in a mouse model of Buruli ulcer

por Converse, Paul J., Almeida, Deepak V., Tasneen, Rokeya, Saini, Vikram, Tyagi, Sandeep, Ammerman, Nicole C., Li, Si-Yang, Anders, Nicole M., Rudek, Michelle A., Grosset, Jacques H., Nuermberger, Eric L.
Publicado 2018

The effect of an adenosine A(2A) agonist on intra-tumoral concentrations of temozolomide in patients with recurrent glioblastoma

por Jackson, Sadhana, Weingart, Jon, Nduom, Edjah K., Harfi, Thura T., George, Richard T., McAreavey, Dorothea, Ye, Xiaobu, Anders, Nicole M., Peer, Cody, Figg, William D., Gilbert, Mark, Rudek, Michelle A., Grossman, Stuart A.
Publicado 2018

A Small Molecule Inhibitor of ETV1, YK-4-279, Prevents Prostate Cancer Growth and Metastasis in a Mouse Xenograft Model

por Rahim, Said, Minas, Tsion, Hong, Sung-Hyeok, Justvig, Sarah, Çelik, Haydar, Kont, Yasemin Saygideger, Han, Jenny, Kallarakal, Abraham T., Kong, Yali, Rudek, Michelle A., Brown, Milton L., Kallakury, Bhaskar, Toretsky, Jeffrey A., Üren, Aykut
Publicado 2014

Safety and Preliminary Efficacy of Vorinostat With R-EPOCH in High-risk HIV-associated Non-Hodgkin’s Lymphoma (AMC-075)

por Ramos, Juan C., Sparano, Joseph A., Rudek, Michelle A., Moore, Page C., Cesarman, Ethel, Reid, Erin G., Henry, David, Ratner, Lee, Aboulafia, David, Lee, Jeanette Y., Ambinder, Richard F., Mitsuyasu, Ronald, Noy, Ariela
Publicado 2018

A phase 1/PK study of Sunitinib with highly active antiretroviral therapy (HAART) in HIV+ patients with solid tumors: AIDS malignancy consortium study 061

por Deeken, John F, Rudek, Michelle A, Moore, Page C, Aboulafia, David, Sullivan, Ryan, Gerecitano, John, Cianfrocca, Mary, Henry, David, Ratner, Lee, Dezube, Bruce, Mosby, Kimberly, Tibbals, Melinda, Little, Richard F, Ivy, S P, Mitsuyasu, Ronald T
Publicado 2012

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs

por Fox, Jennifer M., Moynihan, James R., Mott, Bryan T., Mazzone, Jennifer R., Anders, Nicole M., Brown, Patrick A., Rudek, Michelle A., Liu, Jun O., Arav-Boger, Ravit, Posner, Gary H., Civin, Curt I., Chen, Xiaochun
Publicado 2016

Covalent Rpn13-Binding Inhibitors for the Treatment of Ovarian Cancer

por Anchoori, Ravi K., Jiang, Rosie, Peng, Shiwen, Soong, Ruey-shyang, Algethami, Aliyah, Rudek, Michelle A., Anders, Nicole, Hung, Chien-Fu, Chen, Xiang, Lu, Xiuxiu, Kayode, Olumide, Dyba, Marzena, Walters, Kylie J., Roden, Richard B. S.
Publicado 2018

HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy

por Salman, Shaima, Meyers, David J., Wicks, Elizabeth E., Lee, Sophia N., Datan, Emmanuel, Thomas, Aline M., Anders, Nicole M., Hwang, Yousang, Lyu, Yajing, Yang, Yongkang, Jackson, Walter, Dordai, Dominic, Rudek, Michelle A., Semenza, Gregg L.
Publicado 2022