Expanding cultural and ancestral representation in psychiatric genetic studies

por Kang, Jooeun, Ruderfer, Douglas M.
Publicado 2020

Family-based genetic risk prediction of multifactorial disease

por Ruderfer, Douglas M, Korn, Joshua, Purcell, Shaun M
Publicado 2010

Cis-regulatory Landscape Size, Constraint, and Tissue Specificity Associate with Gene Function and Expression

por Benton, Mary Lauren, Ruderfer, Douglas M, Capra, John A
Publicado 2023

Mapping the landscape of lineage-specific dynamic regulation of gene expression using single-cell transcriptomics and application to genetics of complex disease

por Abe, Hanna, Lin, Phillip, Zhou, Dan, Ruderfer, Douglas M., Gamazon, Eric R.
Publicado 2023

Genome-Wide Analysis of Nucleotide-Level Variation in Commonly Used Saccharomyces cerevisiae Strains

por Schacherer, Joseph, Ruderfer, Douglas M., Gresham, David, Dolinski, Kara, Botstein, David, Kruglyak, Leonid
Publicado 2007

Learning Opportunities for Drug Repositioning via GWAS and PheWAS Findings

por Yin, Wen, Gao, Cheng, Xu, Yaomin, Li, Bingshan, Ruderfer, Douglas M., Chen, You
Publicado 2018

Using Expression and Genotype to Predict Drug Response in Yeast

por Ruderfer, Douglas M., Roberts, David C., Schreiber, Stuart L., Perlstein, Ethan O., Kruglyak, Leonid
Publicado 2009

Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado 2006

Correction: Telomere Length as a Quantitative Trait: Genome-Wide Survey and Genetic Mapping of Telomere Length-Control Genes in Yeast

por Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Publicado 2006

Significant shared heritability underlies suicide attempt and clinically predicted probability of attempting suicide

por Ruderfer, Douglas M., Walsh, Colin G., Aguirre, Matthew W., Tanigawa, Yosuke, Ribeiro, Jessica D., Franklin, Joseph C., Rivas, Manuel A.
Publicado 2019

Improving ascertainment of suicidal ideation and suicide attempt with natural language processing

por Bejan, Cosmin A., Ripperger, Michael, Wilimitis, Drew, Ahmed, Ryan, Kang, JooEun, Robinson, Katelyn, Morley, Theodore J., Ruderfer, Douglas M., Walsh, Colin G.
Publicado 2022

Identifying modifiable comorbidities of schizophrenia by integrating electronic health records and polygenic risk

por Vessels, Tess, Strayer, Nicholas, Choi, Karmel W., Lee, Hyunjoon, Zhang, Siwei, Han, Lide, Morley, Theodore J., Smoller, Jordan W., Xu, Yaomin, Ruderfer, Douglas M.
Publicado 2023

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains

por Hoffman, Gabriel E., Hartley, Brigham J., Flaherty, Erin, Ladran, Ian, Gochman, Peter, Ruderfer, Douglas M., Stahl, Eli A., Rapoport, Judith, Sklar, Pamela, Brennand, Kristen J.
Publicado 2017

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

por Ruderfer, Douglas M., Hamamsy, Tymor, Lek, Monkol, Karczewski, Konrad J., Kavanagh, David, Samocha, Kaitlin E., Daly, Mark J., MacArthur, Daniel G., Fromer, Menachem, Purcell, Shaun M.
Publicado 2016

Improving genetic prediction by leveraging genetic correlations among human diseases and traits

por Maier, Robert M., Zhu, Zhihong, Lee, Sang Hong, Trzaskowski, Maciej, Ruderfer, Douglas M., Stahl, Eli A., Ripke, Stephan, Wray, Naomi R., Yang, Jian, Visscher, Peter M., Robinson, Matthew R.
Publicado 2018

Evaluating the impact of modeling choices on the performance of integrated genetic and clinical models

por Morley, Theodore J., Willimitis, Drew, Ripperger, Michael, Lee, Hyunjoon, Han, Lide, Zhou, Yu, Kang, Jooeun, Davis, Lea K., Smoller, Jordan W., Choi, Karmel W., Walsh, Colin G., Ruderfer, Douglas M.
Publicado 2023

Increased burden of ultra-rare protein-altering variants among 4,877 individuals with schizophrenia

por Genovese, Giulio, Fromer, Menachem, Stahl, Eli A., Ruderfer, Douglas M., Chambert, Kimberly, Landén, Mikael, Moran, Jennifer L., Purcell, Shaun M., Sklar, Pamela, Sullivan, Patrick F., Hultman, Christina M., McCarroll, Steven A.
Publicado 2016

The ExAC browser: displaying reference data information from over 60 000 exomes

por Karczewski, Konrad J., Weisburd, Ben, Thomas, Brett, Solomonson, Matthew, Ruderfer, Douglas M., Kavanagh, David, Hamamsy, Tymor, Lek, Monkol, Samocha, Kaitlin E., Cummings, Beryl B., Birnbaum, Daniel, Daly, Mark J., MacArthur, Daniel G.
Publicado 2017

Genetic validation of bipolar disorder identified by automated phenotyping using electronic health records

por Chen, Chia-Yen, Lee, Phil H., Castro, Victor M., Minnier, Jessica, Charney, Alexander W., Stahl, Eli A., Ruderfer, Douglas M., Murphy, Shawn N., Gainer, Vivian, Cai, Tianxi, Jones, Ian, Pato, Carlos N., Pato, Michele T., Landén, Mikael, Sklar, Pamela, Perlis, Roy H., Smoller, Jordan W.
Publicado 2018

Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

por Dennis, Jessica K., Sealock, Julia M., Straub, Peter, Lee, Younga H., Hucks, Donald, Actkins, Ky’Era, Faucon, Annika, Feng, Yen-Chen Anne, Ge, Tian, Goleva, Slavina B., Niarchou, Maria, Singh, Kritika, Morley, Theodore, Smoller, Jordan W., Ruderfer, Douglas M., Mosley, Jonathan D., Chen, Guanhua, Davis, Lea K.
Publicado 2021