Selectivity of Lewy body protein interactions along the aggregation pathway of α-synuclein

por Leitão, André D. G., Rudolffi-Soto, Paulina, Chappard, Alexandre, Bhumkar, Akshay, Lau, Derrick, Hunter, Dominic J. B., Gambin, Yann, Sierecki, Emma
Publicado 2021

Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor

por Moustaqil, Mehdi, Fontaine, Frank, Overman, Jeroen, McCann, Alex, Bailey, Timothy L, Rudolffi Soto, Paulina, Bhumkar, Akshay, Giles, Nichole, Hunter, Dominic J B, Gambin, Yann, Francois, Mathias, Sierecki, Emma
Publicado 2018

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

por Moustaqil, Mehdi, Ollivier, Emma, Chiu, Hsin-Ping, Van Tol, Sarah, Rudolffi-Soto, Paulina, Stevens, Christian, Bhumkar, Akshay, Hunter, Dominic J. B., Freiberg, Alexander N., Jacques, David, Lee, Benhur, Sierecki, Emma, Gambin, Yann
Publicado 2021

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

por McCann, Alex J, Lou, Jieqiong, Moustaqil, Mehdi, Graus, Matthew S, Blum, Ailisa, Fontaine, Frank, Liu, Hui, Luu, Winnie, Rudolffi-Soto, Paulina, Koopman, Peter, Sierecki, Emma, Gambin, Yann, Meunier, Frédéric A, Liu, Zhe, Hinde, Elizabeth, Francois, Mathias
Publicado 2021