The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family

por Esteves, Francisco, Rueff, José, Kranendonk, Michel
Publicado 2021

Copy number variations and constitutional chromothripsis (Review)

por Brás, Aldina, Rodrigues, António Sebastião, Rueff, José
Publicado 2020

A novel heterozygous missense mutation in the UMOD gene responsible for Familial Juvenile Hyperuricemic Nephropathy

por Calado, Joaquim, Gaspar, Augusta, Clemente, Carla, Rueff, José
Publicado 2005

MicroRNAs and cancer drug resistance: over two thousand characters in search of a role

por Gomes, Bruno Costa, Rueff, José, Rodrigues, António Sebastião
Publicado 2019

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding

por Esteves, Francisco, Urban, Philippe, Rueff, José, Truan, Gilles, Kranendonk, Michel
Publicado 2020

Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance

por Armada, Ana, Gomes, Bruno Costa, Viveiros, Miguel, Rueff, José, Rodrigues, António Sebastião
Publicado 2019

Integration of HIV in the Human Genome: Which Sites Are Preferential? A Genetic and Statistical Assessment

por Gonçalves, Juliana, Moreira, Elsa, Sequeira, Inês J., Rodrigues, António S., Rueff, José, Brás, Aldina
Publicado 2016

ABC Efflux Transporters and the Circuitry of miRNAs: Kinetics of Expression in Cancer Drug Resistance

por Gomes, Bruno C., Honrado, Mónica, Armada, Ana, Viveiros, Miguel, Rueff, José, Rodrigues, António S.
Publicado 2020

The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells

por Barata, Isabel S., Gomes, Bruno C., Rodrigues, António S., Rueff, José, Kranendonk, Michel, Esteves, Francisco
Publicado 2022

Genetic determinants and absence of breast cancer in Xavante Indians in Sangradouro Reserve, Brazil

por Zhou, Yan, Russo, Jose, Rueff, José, Pires, Marcelo A. M., de Castro, Guilherme Bezerra
Publicado 2023

Male and female breast cancer: the two faces of the same genetic susceptibility coin

por Silva, Susana Nunes, Gomes, Bruno Costa, André, Saudade, Félix, Ana, Rodrigues, António Sebastião, Rueff, José
Publicado 2021

Association of common variants in mismatch repair genes and breast cancer susceptibility: a multigene study

por Conde, João, Silva, Susana N, Azevedo, Ana P, Teixeira, Valdemar, Pina, Julieta Esperança, Rueff, José, Gaspar, Jorge F
Publicado 2009

DNA repair genes polymorphisms and genetic susceptibility to Philadelphia-negative myeloproliferative neoplasms in a Portuguese population: The role of base excision repair genes p...

por Azevedo, Ana P., Silva, Susana N., De Lima, João P., Reichert, Alice, Lima, Fernando, Júnior, Esmeraldina, Rueff, José
Publicado 2017

Micronuclei Formation upon Radioiodine Therapy for Well-Differentiated Thyroid Cancer: The Influence of DNA Repair Genes Variants

por S. Santos, Luís, M. Gil, Octávia, N. Silva, Susana, C. Gomes, Bruno, C. Ferreira, Teresa, Limbert, Edward, Rueff, José
Publicado 2020

The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners

por Esteves, Francisco, Campelo, Diana, Gomes, Bruno Costa, Urban, Philippe, Bozonnet, Sophie, Lautier, Thomas, Rueff, José, Truan, Gilles, Kranendonk, Michel
Publicado 2020

Corrigendum: The Role of the FMN-Domain of Human Cytochrome P450 Oxidoreductase in Its Promiscuous Interactions With Structurally Diverse Redox Partners

por Esteves, Francisco, Campelo, Diana, Gomes, Bruno Costa, Urban, Philippe, Bozonnet, Sophie, Lautier, Thomas, Rueff, José, Truan, Gilles, Kranendonk, Michel
Publicado 2020

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism

por Esteves, Francisco, Almeida, Cristina M. M., Silva, Sofia, Saldanha, Inês, Urban, Philippe, Rueff, José, Pompon, Denis, Truan, Gilles, Kranendonk, Michel
Publicado 2023

Probing the Role of the Hinge Segment of Cytochrome P450 Oxidoreductase in the Interaction with Cytochrome P450

por Campelo, Diana, Esteves, Francisco, Brito Palma, Bernardo, Costa Gomes, Bruno, Rueff, José, Lautier, Thomas, Urban, Philippe, Truan, Gilles, Kranendonk, Michel
Publicado 2018

Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients

por Gomes, Bruno Costa, Peixinho, Nuno, Pisco, Rita, Gromicho, Marta, Pronto-Laborinho, Ana Catarina, Rueff, José, de Carvalho, Mamede, Rodrigues, António Sebastião
Publicado 2023

BRCA1 VUS: A functional analysis to differentiate pathogenic from benign variants identified in clinical diagnostic panels for breast cancer

por Lourenço, Rita Adubeiro, Lança, Miguel, Monteiro Gil, Octávia, Cardoso, Joana, Lourenço, Teresa, Pereira-Leal, José B., Rodrigues, António Sebastião, Rueff, José, Nunes Silva, Susana
Publicado 2023