Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function

por Ruepp, Marc-David, Schweingruber, Christoph, Kleinschmidt, Nicole, Schümperli, Daniel
Publicado 2011

Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways

por Metze, Stefanie, Herzog, Veronika A., Ruepp, Marc-David, Mühlemann, Oliver
Publicado 2013

The binding orientation of epibatidine at α7 nACh receptors

por Thompson, Andrew J., Metzger, Simon, Lochner, Martin, Ruepp, Marc-David
Publicado 2017

Identification of Interactions in the NMD Complex Using Proximity-Dependent Biotinylation (BioID)

por Schweingruber, Christoph, Soffientini, Paolo, Ruepp, Marc-David, Bachi, Angela, Mühlemann, Oliver
Publicado 2016

The binding orientations of structurally-related ligands can differ; A cautionary note

por Ruepp, Marc-David, Wei, Hao, Leuenberger, Michele, Lochner, Martin, Thompson, Andrew J.
Publicado 2017

The emerging role of minor intron splicing in neurological disorders

por Jutzi, Daniel, Akinyi, Maureen V., Mechtersheimer, Jonas, Frilander, Mikko J., Ruepp, Marc-David
Publicado 2018

Human vtRNA1-1 Levels Modulate Signaling Pathways and Regulate Apoptosis in Human Cancer Cells

por Bracher, Lisamaria, Ferro, Iolanda, Pulido-Quetglas, Carlos, Ruepp, Marc-David, Johnson, Rory, Polacek, Norbert
Publicado 2020

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3′-end processing of animal histone mRNAs

por Ruepp, Marc-David, Vivarelli, Silvia, Pillai, Ramesh S., Kleinschmidt, Nicole, Azzouz, Teldja N., Barabino, Silvia M. L., Schümperli, Daniel
Publicado 2010

Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39

por Campagne, Sébastien, Jutzi, Daniel, Malard, Florian, Matoga, Maja, Romane, Ksenija, Feldmuller, Miki, Colombo, Martino, Ruepp, Marc-David, Allain, Frédéric H-T.
Publicado 2023

Paraquat Modulates Alternative Pre-mRNA Splicing by Modifying the Intracellular Distribution of SRPK2

por Vivarelli, Silvia, Lenzken, Silvia C., Ruepp, Marc-David, Ranzini, Francesco, Maffioletti, Andrea, Alvarez, Reinaldo, Mühlemann, Oliver, Barabino, Silvia M. L.
Publicado 2013

CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells

por Reber, Stefan, Mechtersheimer, Jonas, Nasif, Sofia, Benitez, Julio Aguila, Colombo, Martino, Domanski, Michal, Jutzi, Daniel, Hedlund, Eva, Ruepp, Marc-David
Publicado 2018

ALS-linked FUS mutants affect the localization of U7 snRNP and replication-dependent histone gene expression in human cells

por Gadgil, Ankur, Walczak, Agnieszka, Stępień, Agata, Mechtersheimer, Jonas, Nishimura, Agnes Lumi, Shaw, Christopher E., Ruepp, Marc-David, Raczyńska, Katarzyna Dorota
Publicado 2021

Heterozygous expression of the Alzheimer’s disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses

por Solomon, Shiden, Sampathkumar, Nirmal Kumar, Carre, Ivo, Mondal, Mrityunjoy, Chennell, George, Vernon, Anthony C., Ruepp, Marc-David, Mitchell, Jacqueline C
Publicado 2022

A fluorescent approach for identifying P2X1 ligands

por Ruepp, Marc-David, Brozik, James A., de Esch, Iwan J.P., Farndale, Richard W., Murrell-Lagnado, Ruth D., Thompson, Andrew J.
Publicado 2015

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors

por Raczynska, Katarzyna Dorota, Ruepp, Marc-David, Brzek, Aleksandra, Reber, Stefan, Romeo, Valentina, Rindlisbacher, Barbara, Heller, Manfred, Szweykowska-Kulinska, Zofia, Jarmolowski, Artur, Schümperli, Daniel
Publicado 2015

The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

por Reber, Stefan, Jutzi, Daniel, Lindsay, Helen, Devoy, Anny, Mechtersheimer, Jonas, Levone, Brunno Rocha, Domanski, Michal, Bentmann, Eva, Dormann, Dorothee, Mühlemann, Oliver, Barabino, Silvia M L, Ruepp, Marc-David
Publicado 2021

Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis

por Jutzi, Daniel, Campagne, Sébastien, Schmidt, Ralf, Reber, Stefan, Mechtersheimer, Jonas, Gypas, Foivos, Schweingruber, Christoph, Colombo, Martino, von Schroetter, Christine, Loughlin, Fionna E., Devoy, Anny, Hedlund, Eva, Zavolan, Mihaela, Allain, Frédéric H.-T., Ruepp, Marc-David
Publicado 2020

Targeting CD47 in Anaplastic Thyroid Carcinoma Enhances Tumor Phagocytosis by Macrophages and Is a Promising Therapeutic Strategy

por Schürch, Christian M., Roelli, Matthias A., Forster, Stefan, Wasmer, Marie-Hélène, Brühl, Frido, Maire, Renaud S., Di Pancrazio, Sergio, Ruepp, Marc-David, Giger, Roland, Perren, Aurel, Schmitt, Anja M., Krebs, Philippe, Charles, Roch-Philippe, Dettmer, Matthias S.
Publicado 2019

FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

por Levone, Brunno R., Lenzken, Silvia C., Antonaci, Marco, Maiser, Andreas, Rapp, Alexander, Conte, Francesca, Reber, Stefan, Mechtersheimer, Jonas, Ronchi, Antonella E., Mühlemann, Oliver, Leonhardt, Heinrich, Cardoso, M. Cristina, Ruepp, Marc-David, Barabino, Silvia M.L.
Publicado 2021

HNRNPH1 regulates the neuroprotective cold‐shock protein RBM3 expression through poison exon exclusion

por Lin, Julie Qiaojin, Khuperkar, Deepak, Pavlou, Sofia, Makarchuk, Stanislaw, Patikas, Nikolaos, Lee, Flora CY, Zbiegly, Julia M, Kang, Jianning, Field, Sarah F, Bailey, David MD, Freeman, Joshua L, Ule, Jernej, Metzakopian, Emmanouil, Ruepp, Marc‐David, Mallucci, Giovanna R
Publicado 2023