TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation

por Farina, Antonietta Rosella, Cappabianca, Lucia, Gneo, Luciana, Ruggeri, Pierdomenico, Mackay, Andrew Reay
Publicado 2017

Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity

por Farina, Antonietta Rosella, Cappabianca, Lucia, Ruggeri, Pierdomenico, Gneo, Luciana, Maccarone, Rita, Mackay, Andrew Reay
Publicado 2015

Salvianolic Acid B Strikes Back: New Evidence in the Modulation of Expression and Activity of Matrix Metalloproteinase 9 in MDA-MB-231 Human Breast Cancer Cells

por Ianni, Andrea, Ruggeri, Pierdomenico, Bellio, Pierangelo, Martino, Francesco, Celenza, Giuseppe, Martino, Giuseppe, Franceschini, Nicola
Publicado 2022

TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic “Achilles heel” for the TrkAIII o...

por Gneo, Luciana, Ruggeri, Pierdomenico, Cappabianca, Lucia, Farina, Antonietta Rosella, Ianni, Natalia Di, Mackay, Andrew Reay
Publicado 2016

The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII

por Farina, Antonietta Rosella, Cappabianca, Lucia, Ruggeri, Pierdomenico, Gneo, Luciana, Pellegrini, Cristina, Fargnoli, Maria-Concetta, Mackay, Andrew Reay
Publicado 2018

TrkAIII Promotes Microtubule Nucleation and Assembly at the Centrosome in SH-SY5Y Neuroblastoma Cells, Contributing to an Undifferentiated Anaplastic Phenotype

por Farina, Antonietta R., Di Ianni, Natalia, Cappabianca, Lucia, Ruggeri, Pierdomenico, Ragone, Marzia, Ianni, Giulia, Gulino, Alberto, Mackay, Andrew R.
Publicado 2013

The TrkAIII Oncoprotein Inhibits Mitochondrial Free Radical ROS-Induced Death of SH-SY5Y Neuroblastoma Cells by Augmenting SOD2 Expression and Activity at the Mitochondria, within...

por Ruggeri, Pierdomenico, Farina, Antonietta R., Di Ianni, Natalia, Cappabianca, Lucia, Ragone, Marzia, Ianni, Giulia, Gulino, Alberto, Mackay, Andrew R.
Publicado 2014

The Alternative TrkAIII Splice Variant, a Targetable Oncogenic Participant in Human Cutaneous Malignant Melanoma

por Cappabianca, Lucia, Zelli, Veronica, Pellegrini, Cristina, Sebastiano, Michela, Maccarone, Rita, Clementi, Marco, Chiominto, Alessandro, Ruggeri, Pierdomenico, Cardelli, Ludovica, Ruggieri, Marianna, Sbaffone, Maddalena, Fargnoli, Maria-Concetta, Guadagni, Stefano, Farina, Antonietta R., Mackay, Andrew R.
Publicado 2023