MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity

por Yarchoan, Mark, Mohan, Aditya A., Dennison, Lauren, Vithayathil, Teena, Ruggieri, Amanda, Lesinski, Gregory B., Armstrong, Todd D., Azad, Nilofer S., Jaffee, Elizabeth M.
Publicado 2019

Expression of tdTomato and luciferase in a murine lung cancer alters the growth and immune microenvironment of the tumor

por Huang, Lei, Bommireddy, Ramireddy, Munoz, Luis E., Guin, Rohini N., Wei, Changyong, Ruggieri, Amanda, Menon, Ashwathi P., Li, Xiaoxian, Shanmugam, Mala, Owonikoko, Taofeek K., Ramalingam, Suresh S., Selvaraj, Periasamy
Publicado 2021

Suppressive myeloid cells are expanded by biliary tract cancer-derived cytokines in vitro and associate with aggressive disease

por Ware, Michael B., Zaidi, Mohammad Y., Yang, Jennifer, Turgeon, Michael K., Krasinskas, Alyssa, Mace, Thomas A., Keenan, Kaitlin, Farren, Matthew R., Ruggieri, Amanda N., Li, Yiman, Zhang, Chao, Chen, Zhengjia, Young, Gregory S., Elnaggar, Omar, Che, Zheng, Maithel, Shishir K., Bekaii-Saab, Tanios, El-Rayes, Bassel, Lesinski, Gregory B.
Publicado 2020

Dual IL-6 and CTLA-4 blockade regresses pancreatic tumors in a T cell– and CXCR3-dependent manner

por Ware, Michael Brandon, Phillips, Maggie, McQuinn, Christopher, Zaidi, Mohammad Y., Knochelmann, Hannah M., Greene, Emily, Robinson, Brian, Herting, Cameron J., Mace, Thomas A., Chen, Zhengjia, Zhang, Chao, Farren, Matthew R., Ruggieri, Amanda N., Bowers, Jacob S., Shakya, Reena, Farris, Alton B., Young, Gregory, Carson, William E., El-Rayes, Bassel, Paulos, Chrystal M., Lesinski, Gregory B.
Publicado 2023