Activity Based High-Throughput Screening for Novel O-GlcNAc Transferase Substrates Using a Dynamic Peptide Microarray

por Shi, Jie, Sharif, Suhela, Ruijtenbeek, Rob, Pieters, Roland J.
Publicado 2016

Cell Death Triggers Induce MLKL Cleavage in Multiple Myeloma Cells, Which may Promote Cell Death

por Chen, Jing, Wang, Shiyu, Blokhuis, Bart, Ruijtenbeek, Rob, Garssen, Johan, Redegeld, Frank
Publicado 2022

Peptide Arrays

por Zhang, Hong, Pelech, Steven, Ruijtenbeek, Rob, Felgenhauer, Thomas, Bischoff, Ralf, Breitling, Frank, Stadler, Volker
Publicado 2012

Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation

por Sanz, Arturo, Ungureanu, Daniela, Pekkala, Tuija, Ruijtenbeek, Rob, Touw, Ivo P., Hilhorst, Riet, Silvennoinen, Olli
Publicado 2011

C‐Terminal Tag Location Hampers in Vitro Profiling of OGT Peptide Substrates by mRNA Display

por Shi, Jie, Sharif, Suhela, Balsollier, Cyril, Ruijtenbeek, Rob, Pieters, Roland J., Jongkees, Seino A. K.
Publicado 2020

Omega-3 Fatty Acids DHA and EPA Reduce Bortezomib Resistance in Multiple Myeloma Cells by Promoting Glutathione Degradation

por Chen, Jing, Zaal, Esther A., Berkers, Celia R., Ruijtenbeek, Rob, Garssen, Johan, Redegeld, Frank A.
Publicado 2021

Protein-Tyrosine Kinase Activity Profiling in Knock Down Zebrafish Embryos

por Lemeer, Simone, Jopling, Chris, Naji, Faris, Ruijtenbeek, Rob, Slijper, Monique, Heck, Albert J.R., den Hertog, Jeroen
Publicado 2007

Differentiating Benign from Malignant Thyroid Tumors by Kinase Activity Profiling and Dabrafenib BRAF V600E Targeting

por Hilhorst, Riet, van den Berg, Adrienne, Boender, Piet, van Wezel, Tom, Kievits, Tim, de Wijn, Rik, Ruijtenbeek, Rob, Corver, Willem E., Morreau, Hans
Publicado 2023

Inactive immune pathways in triple negative breast cancers that showed resistance to neoadjuvant chemotherapy as inferred from kinase activity profiles

por Sawada, Takeshi, Hilhorst, Riet, Rangarajan, Savithri, Yoshida, Masayuki, Tanabe, Yuko, Tamura, Kenji, Kinoshita, Takayuki, Shimoyama, Tatsu, van Beuningen, Rinie, Ruijtenbeek, Rob, Tsuda, Hitoshi, Koizumi, Fumiaki
Publicado 2018

Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance Short Title: Sensitivity Pre...

por Krayem, Mohamad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem E.
Publicado 2020

Erratum: Krayem, M., et al. Kinome Profiling to Predict Sensitivity to MAPK Inhibition in Melanoma and to Provide New Insights into Intrinsic and Acquired Mechanism of Resistance S...

por Krayem, Mohammad, Aftimos, Philippe, Najem, Ahmad, van den Hooven, Tim, van den Berg, Adriënne, Hovestad-Bijl, Liesbeth, de Wijn, Rik, Hilhorst, Riet, Ruijtenbeek, Rob, Sabbah, Malak, Kerger, Joseph, Awada, Ahmad, Journe, Fabrice, Ghanem, Ghanem E.
Publicado 2020

Cetuximab Prevents Methotrexate-Induced Cytotoxicity in Vitro through Epidermal Growth Factor Dependent Regulation of Renal Drug Transporters

por Caetano-Pinto, Pedro, Jamalpoor, Amer, Ham, Janneke, Goumenou, Anastasia, Mommersteeg, Monique, Pijnenburg, Dirk, Ruijtenbeek, Rob, Sanchez-Romero, Natalia, van Zelst, Bertrand, Heil, Sandra G., Jansen, Jitske, Wilmer, Martijn J., van Herpen, Carla M. L., Masereeuw, Rosalinde
Publicado 2017

Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function

por Van Der Steen, Nele, Keller, Kaylee, Dekker, Henk, Porcelli, Letizia, Honeywell, Richard J., Van Meerloo, Johan, Musters, René J. P., Kathmann, Ietje, Frampton, Adam E., Liu, Daniel S. K., Ruijtenbeek, Rob, Rolfo, Christian, Pauwels, Patrick, Giovannetti, Elisa, Peters, Godefridus J.
Publicado 2020

Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis

por van der Wel, Tom, Hilhorst, Riet, den Dulk, Hans, van den Hooven, Tim, Prins, Nienke M., Wijnakker, Joost A. P. M., Florea, Bogdan I., Lenselink, Eelke B., van Westen, Gerard J. P., Ruijtenbeek, Rob, Overkleeft, Herman S., Kaptein, Allard, Barf, Tjeerd, van der Stelt, Mario
Publicado 2020

Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients

por Buffart, Tineke E., van den Oord, Rosanne A. H. M., van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F. M., van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R., Dekker, Henk, Piersma, Sander R., Pham, Thang V., van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R., Verheul, Henk M. W.
Publicado 2021

Genome-Wide Meta-Analysis Identifies Variants in DSCAM and PDLIM3 That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib

por Diekstra, Meta H. M., Swen, Jesse J., van der Zanden, Loes F. M., Vermeulen, Sita H., Boven, Epie, Mathijssen, Ron H. J., Fukunaga, Koya, Mushiroda, Taisei, Hongo, Fumiya, Oosterwijk, Egbert, Cambon-Thomsen, Anne, Castellano, Daniel, Fritsch, Achim, Donas, Jesus Garcia, Rodriguez-Antona, Cristina, Ruijtenbeek, Rob, Radu, Marius T., Eisen, Tim, Junker, Kerstin, Roessler, Max, Jaehde, Ulrich, Miki, Tsuneharu, Böhringer, Stefan, Kubo, Michiaki, Kiemeney, Lambertus A. L. M., Guchelaar, Henk-Jan
Publicado 2022

Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer

por Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H
Publicado 2020