Resistance mechanism to Notch inhibition and combination therapy in human T-cell acute lymphoblastic leukemia

por Cao, Linlin, Ruiz Buendía, Gustavo A., Fournier, Nadine, Liu, Yuanlong, Armand, Florence, Hamelin, Romain, Pavlou, Maria, Radtke, Freddy
Publicado 2023

MAGI1 Prevents Senescence and Promotes the DNA Damage Response in ER(+) Breast Cancer

por Wörthmüller, Janine, Disler, Simona, Pradervand, Sylvain, Richard, François, Haerri, Lisa, Ruiz Buendía, Gustavo A., Fournier, Nadine, Desmedt, Christine, Rüegg, Curzio
Publicado 2023

µLAS: Sizing of expanded trinucleotide repeats with femtomolar sensitivity in less than 5 minutes

por Malbec, Rémi, Chami, Bayan, Aeschbach, Lorène, Ruiz Buendía, Gustavo A., Socol, Marius, Joseph, Pierre, Leïchlé, Thierry, Trofimenko, Evgeniya, Bancaud, Aurélien, Dion, Vincent
Publicado 2019

Expanded CAG/CTG repeats resist gene silencing mediated by targeted epigenome editing

por Yang, Bin, Borgeaud, Alicia C, Buřičová, Marcela, Aeschbach, Lorène, Rodríguez-Lima, Oscar, Ruiz Buendía, Gustavo A, Cinesi, Cinzia, Taylor, Alysha S, Baubec, Tuncay, Dion, Vincent
Publicado 2021

Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion

por Ruiz Buendía, Gustavo A., Leleu, Marion, Marzetta, Flavia, Vanzan, Ludovica, Tan, Jennifer Y., Ythier, Victor, Randall, Emma L., Marques, Ana C., Baubec, Tuncay, Murr, Rabih, Xenarios, Ioannis, Dion, Vincent
Publicado 2020

Tcf1 is essential for initiation of oncogenic Notch1-driven chromatin topology in T-ALL

por Antoszewski, Mateusz, Fournier, Nadine, Ruiz Buendía, Gustavo A., Lourenco, Joao, Liu, Yuanlong, Sugrue, Tara, Dubey, Christelle, Nkosi, Marianne, Pritchard, Colin E.J., Huijbers, Ivo J., Segat, Gabriela C., Alonso-Moreno, Sandra, Serracanta, Elisabeth, Belver, Laura, Ferrando, Adolfo A., Ciriello, Giovanni, Weng, Andrew P., Koch, Ute, Radtke, Freddy
Publicado 2022