Basal shuttle of NF-κB/IκBα in resting T lymphocytes regulates HIV-1 LTR dependent expression

por Coiras, Mayte, López-Huertas, María Rosa, Rullas, Joaquín, Mittelbrunn, Maria, Alcamí, José
Publicado 2007

X-ray-based virtual slicing of TB-infected lungs

por Ortega-Gil, Ana, Vaquero, Juan José, Gonzalez-Arjona, Mario, Rullas, Joaquín, Muñoz-Barrutia, Arrate
Publicado 2019

The multistate tuberculosis pharmacometric model: a semi-mechanistic pharmacokinetic-pharmacodynamic model for studying drug effects in an acute tuberculosis mouse model

por Chen, Chunli, Ortega, Fatima, Rullas, Joaquin, Alameda, Laura, Angulo-Barturen, Iñigo, Ferrer, Santiago, Simonsson, Ulrika SH
Publicado 2017

Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

por Rullas, Joaquín, Dhar, Neeraj, McKinney, John D., García-Pérez, Adolfo, Lelievre, Joël, Diacon, Andreas H., Hugonnet, Jean-Emmanuel, Arthur, Michel, Angulo-Barturen, Iñigo, Barros-Aguirre, David, Ballell, Lluís
Publicado 2015

Activity of Oral Tebipenem-Avibactam in a Mouse Model of Mycobacterium abscessus Lung Infection

por Negatu, Dereje A., González del Río, Rubén, Cacho-Izquierdo, Mónica, Barros-Aguirre, David, Lelievre, Joël, Rullas, Joaquín, Casado, Patricia, Ganapathy, Uday S., Zimmerman, Matthew D., Gengenbacher, Martin, Dartois, Véronique, Dick, Thomas
Publicado 2023

Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface

por Abrahams, Katherine A., Cox, Jonathan A. G., Fütterer, Klaus, Rullas, Joaquín, Ortega-Muro, Fátima, Loman, Nicholas J., Moynihan, Patrick J., Pérez-Herrán, Esther, Jiménez, Elena, Esquivias, Jorge, Barros, David, Ballell, Lluís, Alemparte, Carlos, Besra, Gurdyal S.
Publicado 2017

A Murine Model of falciparum-Malaria by In Vivo Selection of Competent Strains in Non-Myelodepleted Mice Engrafted with Human Erythrocytes

por Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Mulet, Teresa, Rullas, Joaquín, Herreros, Esperanza, Ferrer, Santiago, Jiménez, Elena, Mendoza, Alfonso, Regadera, Javier, Rosenthal, Philip J., Bathurst, Ian, Pompliano, David L., Gómez de las Heras, Federico, Gargallo-Viola, Domingo
Publicado 2008

Improved BM212 MmpL3 Inhibitor Analogue Shows Efficacy in Acute Murine Model of Tuberculosis Infection

por Poce, Giovanna, Bates, Robert H., Alfonso, Salvatore, Cocozza, Martina, Porretta, Giulio Cesare, Ballell, Lluís, Rullas, Joaquin, Ortega, Fátima, De Logu, Alessandro, Agus, Emanuela, La Rosa, Valentina, Pasca, Maria Rosalia, De Rossi, Edda, Wae, Baojie, Franzblau, Scott G., Manetti, Fabrizio, Botta, Maurizio, Biava, Mariangela
Publicado 2013

Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculo...

por Sibley, Laura, White, Andrew D., Sarfas, Charlotte, Gullick, Jennie, Gleeson, Fergus, Lanni, Faye, Clark, Simon, Rayner, Emma, Ferrer-Bazaga, Santiago, Ortega-Muro, Fatima, Alameda, Laura, Rullas, Joaquin, Sousa, Veronica, Martinez, Marisa, Angulo-Barturen, Inigo, Garcia, Adolfo, Vaquero, Juan José, Pertinez, Henry E., Davies, Geraint, Dennis, Mike, Williams, Ann, Sharpe, Sally
Publicado 2022

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB

por Cleghorn, Laura A. T., Ray, Peter C., Odingo, Joshua, Kumar, Anuradha, Wescott, Heather, Korkegian, Aaron, Masquelin, Thierry, Lopez Moure, Abraham, Wilson, Caroline, Davis, Susan, Huggett, Margaret, Turner, Penelope, Smith, Alasdair, Epemolu, Ola, Zuccotto, Fabio, Riley, Jennifer, Scullion, Paul, Shishikura, Yoko, Ferguson, Liam, Rullas, Joaquin, Guijarro, Laura, Read, Kevin D., Green, Simon R., Hipskind, Phil, Parish, Tanya, Wyatt, Paul G.
Publicado 2018

Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] Analogues with Bactericidal Efficacy against Mycobacterium tub...

por Remuiñán, Modesto J., Pérez-Herrán, Esther, Rullás, Joaquín, Alemparte, Carlos, Martínez-Hoyos, María, Dow, David J., Afari, Johnson, Mehta, Nalini, Esquivias, Jorge, Jiménez, Elena, Ortega-Muro, Fátima, Fraile-Gabaldón, María Teresa, Spivey, Vickey L., Loman, Nicholas J., Pallen, Mark J., Constantinidou, Chrystala, Minick, Douglas J., Cacho, Mónica, Rebollo-López, María José, González, Carolina, Sousa, Verónica, Angulo-Barturen, Iñigo, Mendoza-Losana, Alfonso, Barros, David, Besra, Gurdyal S., Ballell, Lluís, Cammack, Nicholas
Publicado 2013

Identification of KasA as the cellular target of an anti-tubercular scaffold

por Abrahams, Katherine A., Chung, Chun-wa, Ghidelli-Disse, Sonja, Rullas, Joaquín, Rebollo-López, María José, Gurcha, Sudagar S., Cox, Jonathan A. G., Mendoza, Alfonso, Jiménez-Navarro, Elena, Martínez-Martínez, María Santos, Neu, Margarete, Shillings, Anthony, Homes, Paul, Argyrou, Argyrides, Casanueva, Ruth, Loman, Nicholas J., Moynihan, Patrick J., Lelièvre, Joël, Selenski, Carolyn, Axtman, Matthew, Kremer, Laurent, Bantscheff, Marcus, Angulo-Barturen, Iñigo, Izquierdo, Mónica Cacho, Cammack, Nicholas C., Drewes, Gerard, Ballell, Lluis, Barros, David, Besra, Gurdyal S., Bates, Robert H.
Publicado 2016

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

por Palencia, Andrés, Li, Xianfeng, Bu, Wei, Choi, Wai, Ding, Charles Z., Easom, Eric E., Feng, Lisa, Hernandez, Vincent, Houston, Paul, Liu, Liang, Meewan, Maliwan, Mohan, Manisha, Rock, Fernando L., Sexton, Holly, Zhang, Suoming, Zhou, Yasheen, Wan, Baojie, Wang, Yuehong, Franzblau, Scott G., Woolhiser, Lisa, Gruppo, Veronica, Lenaerts, Anne J., O'Malley, Theresa, Parish, Tanya, Cooper, Christopher B., Waters, M. Gerard, Ma, Zhenkun, Ioerger, Thomas R., Sacchettini, James C., Rullas, Joaquín, Angulo-Barturen, Iñigo, Pérez-Herrán, Esther, Mendoza, Alfonso, Barros, David, Cusack, Stephen, Plattner, Jacob J., Alley, M. R. K.
Publicado 2016

Identification of β-Lactams Active against Mycobacterium tuberculosis by a Consortium of Pharmaceutical Companies and Academic Institutions

por Gold, Ben, Zhang, Jun, Quezada, Landys Lopez, Roberts, Julia, Ling, Yan, Wood, Madeleine, Shinwari, Wasima, Goullieux, Laurent, Roubert, Christine, Fraisse, Laurent, Bacqué, Eric, Lagrange, Sophie, Filoche-Rommé, Bruno, Vieth, Michal, Hipskind, Philip A., Jungheim, Louis N., Aubé, Jeffrey, Scarry, Sarah M., McDonald, Stacey L., Li, Kelin, Perkowski, Andrew, Nguyen, Quyen, Dartois, Véronique, Zimmerman, Matthew, Olsen, David B., Young, Katherine, Bonnett, Shilah, Joerss, Douglas, Parish, Tanya, Boshoff, Helena I., Arora, Kriti, Barry, Clifton E., Guijarro, Laura, Anca, Sara, Rullas, Joaquín, Rodríguez-Salguero, Beatriz, Martínez-Martínez, Maria S., Porras-De Francisco, Esther, Cacho, Monica, Barros-Aguirre, David, Smith, Paul, Berthel, Steven J., Nathan, Carl, Bates, Robert H.
Publicado 2022