The Role of Nrf2 and Cytoprotection in Regulating Chemotherapy Resistance of Human Leukemia Cells

por Rushworth, Stuart A., MacEwan, David J.
Publicado 2011

Pulling the plug – halting cancer's theft of mitochondria

por Marlein, Christopher R., Zaitseva, Lyubov, Rushworth, Stuart A.
Publicado 2017

The Role of PI3K Isoforms in Regulating Bone Marrow Microenvironment Signaling Focusing on Acute Myeloid Leukemia and Multiple Myeloma

por Piddock, Rachel E., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2017

Epigallocatechin activates haem oxygenase-1 expression via protein kinase Cδ and Nrf2

por Ogborne, Richard M., Rushworth, Stuart A., O’Connell, Maria A.
Publicado 2008

Acute Myeloid Leukaemia Drives Metabolic Changes in the Bone Marrow Niche

por Maynard, Rebecca S., Hellmich, Charlotte, Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2022

Bone Marrow Senescence and the Microenvironment of Hematological Malignancies

por Hellmich, Charlotte, Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2020

Oxidative Stress Responses and NRF2 in Human Leukaemia

por Abdul-Aziz, Amina, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

FLIP regulation of HO-1 and TNF signalling in human acute myeloid leukemia provides a unique secondary anti-apoptotic mechanism

por Rushworth, Stuart A, Zaitseva, Lyubov, Langa, Susana, Bowles, Kristian M, MacEwan, David J
Publicado 2010

Protection of acute myeloid leukaemia cells from apoptosis induced by front-line chemotherapeutics is mediated by haem oxygenase-1

por Heasman, Sally-Anne, Zaitseva, Lyubov, Bowles, Kristian M., Rushworth, Stuart A., MacEwan, David J.
Publicado 2011

Mitochondrial oxidative phosphorylation in cutaneous melanoma

por Kumar, Prakrit R., Moore, Jamie A., Bowles, Kristian M., Rushworth, Stuart A., Moncrieff, Marc D.
Publicado 2020

Single-cell gene and isoform expression analysis reveals signatures of ageing in haematopoietic stem and progenitor cells

por Mincarelli, Laura, Uzun, Vladimir, Wright, David, Scoones, Anita, Rushworth, Stuart A., Haerty, Wilfried, Macaulay, Iain C.
Publicado 2023

Understanding the role of NRF2-regulated miRNAs in human malignancies

por Shah, Niraj M, Rushworth, Stuart A, Murray, Megan Y, Bowles, Kristian M, MacEwan, David J
Publicado 2013

Targeting BTK for the treatment of FLT3-ITD mutated acute myeloid leukemia

por Pillinger, Genevra, Abdul-Aziz, Amina, Zaitseva, Lyubov, Lawes, Matthew, MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2015

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML

por Zaitseva, Lyubov, Murray, Megan Y., Shafat, Manar S., Lawes, Matthew J., MacEwan, David J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2014

Myeloma-derived macrophage inhibitory factor regulates bone marrow stromal cell-derived IL-6 via c-MYC

por Piddock, Rachel E., Marlein, Christopher R., Abdul-Aziz, Amina, Shafat, Manar S., Auger, Martin J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2018

Venetoclax and Daratumumab combination treatment demonstrates pre-clinical efficacy in mouse models of Acute Myeloid Leukemia

por Mistry, Jayna J, Hellmich, Charlotte, Lambert, Amelia, Moore, Jamie A, Jibril, Aisha, Collins, Angela, Bowles, Kristian M, Rushworth, Stuart A
Publicado 2021

Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice

por Isaacs-Ten, Anna, Moreno-Gonzalez, Mar, Bone, Caitlin, Martens, Andre, Bernuzzi, Federico, Ludwig, Tobias, Hellmich, Charlotte, Hiller, Karsten, Rushworth, Stuart A., Beraza, Naiara
Publicado 2021

Targeting PI3Kδ and PI3Kγ signalling disrupts human AML survival and bone marrow stromal cell mediated protection

por Pillinger, Genevra, Loughran, Niamh V., Piddock, Rachel E., Shafat, Manar S., Zaitseva, Lyubov, Abdul-Aziz, Amina, Lawes, Matthew J., Bowles, Kristian M., Rushworth, Stuart A.
Publicado 2016

Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction

por Chandran, Sujay, Watkins, Johnathan, Abdul‐Aziz, Amina, Shafat, Manar, Calvert, Patrick A., Bowles, Kristian M., Flather, Marcus D., Rushworth, Stuart A., Ryding, Alisdair D.
Publicado 2017

Modelling Metabolic Shifts during Cardiomyocyte Differentiation, Iron Deficiency and Transferrin Rescue Using Human Pluripotent Stem Cells

por Johnson, Benjamin B., Reinhold, Johannes, Holmes, Terri L., Moore, Jamie A., Cowell, Verity, Bernardo, Andreia S., Rushworth, Stuart A., Vassiliou, Vassilios, Smith, James G. W.
Publicado 2021