Physiologically Based Modelling of Darunavir/Ritonavir Pharmacokinetics During Pregnancy

por Colbers, Angela, Greupink, Rick, Litjens, Carlijn, Burger, David, Russel, Frans G. M.
Publicado 2015

Statins and Cardiomyocyte Metabolism, Friend or Foe?

por Somers, Tim, Siddiqi, Sailay, Morshuis, Wim J., Russel, Frans G. M., Schirris, Tom J. J.
Publicado 2023

Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

por Verscheijden, Laurens F. M., Koenderink, Jan B., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2019

Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling

por Verscheijden, Laurens F. M., Koenderink, Jan B., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2021

Dissecting Drug-Induced Cytotoxicity and Metabolic Dysfunction in Conditionally Immortalized Human Proximal Tubule Cells

por Hoogstraten, Charlotte A., Smeitink, Jan A. M., Russel, Frans G. M., Schirris, Tom J. J.
Publicado 2022

Regulation of P-Glycoprotein in Renal Proximal Tubule Epithelial Cells by LPS and TNF-α

por Heemskerk, Suzanne, Peters, Janny G. P., Louisse, Jochem, Sagar, Seil, Russel, Frans G. M., Masereeuw, Rosalinde
Publicado 2010

Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia

por Verhagen, Noor E., Koenderink, Jan B., Blijlevens, Nicole M. A., Janssen, Jeroen J. W. M., Russel, Frans G. M.
Publicado 2023

Involvement of VDAC, Bax and Ceramides in the Efflux of AIF from Mitochondria during Curcumin-Induced Apoptosis

por Scharstuhl, Alwin, Mutsaers, Henricus A. M., Pennings, Sebastiaan W. C., Russel, Frans G. M., Wagener, Frank A. D. T. G.
Publicado 2009

Glutathione Status and the Renal Elimination of Inorganic Mercury in the Mrp2(−/−) Mouse

por Bridges, Christy C., Joshee, Lucy, van den Heuvel, Jeroen J. M. W., Russel, Frans G. M., Zalups, Rudolfs K.
Publicado 2013

Modeling mitochondrial dysfunctions in the brain: from mice to men

por Breuer, Megan E., Willems, Peter H. G. M., Russel, Frans G. M., Koopman, Werner J. H., Smeitink, Jan A. M.
Publicado 2011

Assessment of Maternal and Fetal Dolutegravir Exposure by Integrating Ex Vivo Placental Perfusion Data and Physiologically‐Based Pharmacokinetic Modeling

por Freriksen, Jolien J.M., Schalkwijk, Stein, Colbers, Angela P., Abduljalil, Khaled, Russel, Frans G.M., Burger, David M., Greupink, Rick
Publicado 2020

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

por Schalkwijk, Stein, Buaben, Aaron O., Freriksen, Jolien J. M., Colbers, Angela P., Burger, David M., Greupink, Rick, Russel, Frans G. M.
Publicado 2017

Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity

por Schirris, Tom J. J., Ritschel, Tina, Herma Renkema, G., Willems, Peter H. G. M., Smeitink, Jan A. M., Russel, Frans G. M.
Publicado 2015

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

por Koenderink, Jan B., van den Heuvel, Jeroen J. M. W., Bilos, Ab, Vredenburg, Galvin, Vermeulen, Nico P. E., Russel, Frans G. M.
Publicado 2020

Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children

por Verscheijden, Laurens F. M., Litjens, Carlijn H. C., Koenderink, Jan B., Mathijssen, Ron H. J., Verbeek, Marcel M., de Wildt, Saskia N., Russel, Frans G. M.
Publicado 2021

Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia

por Heemskerk, Suzanne, van Koppen, Arianne, van den Broek, Luc, Poelen, Geert J. M., Wouterse, Alfons C., Dijkman, Henry B. P. M., Russel, Frans G. M., Masereeuw, Rosalinde
Publicado 2007

Short-term beneficial effects of methylene blue on kidney damage in septic shock patients

por Heemskerk, Suzanne, van Haren, Frank M. P., Foudraine, Norbert A., Peters, Wilbert H. M., van der Hoeven, Johannes G., Russel, Frans G. M., Masereeuw, Rosalinde, Pickkers, Peter
Publicado 2007

Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis

por Somers, Tim, Allard, Neeltje A. E., Siddiqi, Sailay, Janssen, Margit C. M., Hopman, Maria T. E., Morshuis, Wim J., Russel, Frans G. M., Timmers, Silvie, Schirris, Tom J. J.
Publicado 2023

Assessment of Placental Disposition of Infliximab and Etanercept in Women With Autoimmune Diseases and in the Ex Vivo Perfused Placenta

por Eliesen, Gaby A. M., van Drongelen, Joris, van Hove, Hedwig, Kooijman, Nina I., van den Broek, Petra, de Vries, Annick, Roeleveld, Nel, Russel, Frans G. M., Greupink, Rick
Publicado 2020

Chloroquine Dosing Recommendations for Pediatric COVID‐19 Supported by Modeling and Simulation

por Verscheijden, Laurens F. M., van der Zanden, Tjitske M., van Bussel, Lianne P. M., de Hoop‐Sommen, Marika, Russel, Frans G. M., Johnson, Trevor N., de Wildt, Saskia N.
Publicado 2020