Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

por Sydes, Matthew R, Parmar, Mahesh KB, Mason, Malcolm D, Clarke, Noel W, Amos, Claire, Anderson, John, de Bono, Johann, Dearnaley, David P, Dwyer, John, Green, Charlene, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George, James, Nicholas D
Publicado 2012

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

por James, Nicholas D, Sydes, Matthew R, Mason, Malcolm D, Clarke, Noel W, Anderson, John, Dearnaley, David P, Dwyer, John, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George N, Bertelli, Gianfilippo, Birtle, Alison J, O'Sullivan, Joe M, Protheroe, Andrew, Sheehan, Denise, Srihari, Narayanan, Parmar, Mahesh KB
Publicado 2012

Cost-utility analysis of adding abiraterone acetate plus prednisone/prednisolone to long-term hormone therapy in newly diagnosed advanced prostate cancer in England: Lifetime decis...

por Clarke, Caroline S., Hunter, Rachael M., Gabrio, Andrea, Brawley, Christopher D., Ingleby, Fiona C., Dearnaley, David P., Matheson, David, Attard, Gerhardt, Rush, Hannah L., Jones, Rob J., Cross, William, Parker, Chris, Russell, J. Martin, Millman, Robin, Gillessen, Silke, Malik, Zafar, Lester, Jason F., Wylie, James, Clarke, Noel W., Parmar, Mahesh K. B., Sydes, Matthew R., James, Nicholas D.
Publicado 2022

Adding Celecoxib With or Without Zoledronic Acid for Hormone-Naïve Prostate Cancer: Long-Term Survival Results From an Adaptive, Multiarm, Multistage, Platform, Randomized Controll...

por Mason, Malcolm D., Clarke, Noel W., James, Nicholas D., Dearnaley, David P., Spears, Melissa R., Ritchie, Alastair W.S., Attard, Gerhardt, Cross, William, Jones, Rob J., Parker, Christopher C., Russell, J. Martin, Thalmann, George N., Schiavone, Francesca, Cassoly, Estelle, Matheson, David, Millman, Robin, Rentsch, Cyrill A., Barber, Jim, Gilson, Clare, Ibrahim, Azman, Logue, John, Lydon, Anna, Nikapota, Ashok D., O’Sullivan, Joe M., Porfiri, Emilio, Protheroe, Andrew, Srihari, Narayanan Nair, Tsang, David, Wagstaff, John, Wallace, Jan, Walmsley, Catherine, Parmar, Mahesh K.B., Sydes, Matthew R.
Publicado 2017

Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial

por Parker, Christopher C, James, Nicholas D, Brawley, Christopher D, Clarke, Noel W, Hoyle, Alex P, Ali, Adnan, Ritchie, Alastair W S, Attard, Gerhardt, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gillessen, Silke, Gilson, Clare, Jones, Robert J, Langley, Ruth E, Malik, Zafar I, Mason, Malcolm D, Matheson, David, Millman, Robin, Russell, J Martin, Thalmann, George N, Amos, Claire L, Alonzi, Roberto, Bahl, Amit, Birtle, Alison, Din, Omar, Douis, Hassan, Eswar, Chinnamani, Gale, Joanna, Gannon, Melissa R, Jonnada, Sai, Khaksar, Sara, Lester, Jason F, O'Sullivan, Joe M, Parikh, Omi A, Pedley, Ian D, Pudney, Delia M, Sheehan, Denise J, Srihari, Narayanan Nair, Tran, Anna T H, Parmar, Mahesh K B, Sydes, Matthew R
Publicado 2018

Radiotherapy to the prostate for men with metastatic prostate cancer in the UK and Switzerland: Long-term results from the STAMPEDE randomised controlled trial

por Parker, Chris C., James, Nicholas D., Brawley, Christopher D., Clarke, Noel W., Ali, Adnan, Amos, Claire L., Attard, Gerhardt, Chowdhury, Simon, Cook, Adrian, Cross, William, Dearnaley, David P., Douis, Hassan, Gilbert, Duncan C., Gilson, Clare, Gillessen, Silke, Hoyle, Alex, Jones, Rob J., Langley, Ruth E., Malik, Zafar I., Mason, Malcolm D., Matheson, David, Millman, Robin, Rauchenberger, Mary, Rush, Hannah, Russell, J Martin, Sweeney, Hannah, Bahl, Amit, Birtle, Alison, Capaldi, Lisa, Din, Omar, Ford, Daniel, Gale, Joanna, Henry, Ann, Hoskin, Peter, Kagzi, Mohammed, Lydon, Anna, O’Sullivan, Joe M., Paisey, Sangeeta A., Parikh, Omi, Pudney, Delia, Ramani, Vijay, Robson, Peter, Srihari, Narayanan Nair, Tanguay, Jacob, Parmar, Mahesh K. B., Sydes, Matthew R.
Publicado 2022

Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, plat...

por James, Nicholas D, Sydes, Matthew R, Clarke, Noel W, Mason, Malcolm D, Dearnaley, David P, Spears, Melissa R, Ritchie, Alastair W S, Parker, Christopher C, Russell, J Martin, Attard, Gerhardt, de Bono, Johann, Cross, William, Jones, Rob J, Thalmann, George, Amos, Claire, Matheson, David, Millman, Robin, Alzouebi, Mymoona, Beesley, Sharon, Birtle, Alison J, Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir, Chowdhury, Simon, Cook, Audrey, Elliott, Tony, Gale, Joanna, Gibbs, Stephanie, Graham, John D, Hetherington, John, Hughes, Robert, Laing, Robert, McKinna, Fiona, McLaren, Duncan B, O'Sullivan, Joe M, Parikh, Omi, Peedell, Clive, Protheroe, Andrew, Robinson, Angus J, Srihari, Narayanan, Srinivasan, Rajaguru, Staffurth, John, Sundar, Santhanam, Tolan, Shaun, Tsang, David, Wagstaff, John, Parmar, Mahesh K B
Publicado 2016

Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effective...

por Woods, Beth S., Sideris, Eleftherios, Sydes, Matthew R., Gannon, Melissa R., Parmar, Mahesh K.B., Alzouebi, Mymoona, Attard, Gerhardt, Birtle, Alison J., Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir R., Cook, Audrey, Cross, William R., Dearnaley, David P., Gale, Joanna, Gibbs, Stephanie, Graham, John D., Hughes, Robert, Jones, Rob J., Laing, Robert, Mason, Malcolm D., Matheson, David, McLaren, Duncan B., Millman, Robin, O'Sullivan, Joe M., Parikh, Omi, Parker, Christopher C., Peedell, Clive, Protheroe, Andrew, Ritchie, Alastair W.S., Robinson, Angus, Russell, J. Martin, Simms, Matthew S., Srihari, Narayanan N., Srinivasan, Rajaguru, Staffurth, John N., Sundar, Santhanam, Thalmann, George N., Tolan, Shaun, Tran, Anna T.H., Tsang, David, Wagstaff, John, James, Nicholas D., Sculpher, Mark J.
Publicado 2018

Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled ph...

por Attard, Gerhardt, Murphy, Laura, Clarke, Noel W, Cross, William, Jones, Robert J, Parker, Christopher C, Gillessen, Silke, Cook, Adrian, Brawley, Chris, Amos, Claire L, Atako, Nafisah, Pugh, Cheryl, Buckner, Michelle, Chowdhury, Simon, Malik, Zafar, Russell, J Martin, Gilson, Clare, Rush, Hannah, Bowen, Jo, Lydon, Anna, Pedley, Ian, O'Sullivan, Joe M, Birtle, Alison, Gale, Joanna, Srihari, Narayanan, Thomas, Carys, Tanguay, Jacob, Wagstaff, John, Das, Prantik, Gray, Emma, Alzoueb, Mymoona, Parikh, Omi, Robinson, Angus, Syndikus, Isabel, Wylie, James, Zarkar, Anjali, Thalmann, George, de Bono, Johann S, Dearnaley, David P, Mason, Malcolm D, Gilbert, Duncan, Langley, Ruth E, Millman, Robin, Matheson, David, Sydes, Matthew R, Brown, Louise C, Parmar, Mahesh K B, James, Nicholas D
Publicado 2022

Docetaxel for Nonmetastatic Prostate Cancer: Long-Term Survival Outcomes in the STAMPEDE Randomized Controlled Trial

por James, Nicholas D, Ingleby, Fiona C, Clarke, Noel W, Amos, Claire L, Attard, Gerhardt, Brawley, Christopher D, Chowdhury, Simon, Cross, William, Dearnaley, David P, Gilbert, Duncan C, Gillessen, Silke, Jones, Robert J, Langley, Ruth E, Macnair, Archie, Malik, Zafar I, Mason, Malcolm D, Matheson, David J, Millman, Robin, Parker, Chris C, Rush, Hannah L, Russell, J Martin, Au, Carly, Ritchie, Alastair W S, Mestre, Ricardo Pereira, Ahmed, Imtiaz, Birtle, Alison J, Brock, Susannah J, Das, Prantik, Ford, Victoria A, Gray, Emma K, Hughes, Robert J, Manetta, Caroline B, McLaren, Duncan B, Nikapota, Ashok D, O’Sullivan, Joe M, Perna, Carla, Peedell, Clive, Protheroe, Andrew S, Sundar, Santhanam, Tanguay, Jacob S, Tolan, Shaun P, Wagstaff, John, Wallace, Jan B, Wylie, James P, Zarkar, Anjali, Parmar, Mahesh K B, Sydes, Matthew R
Publicado 2022

Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5‐year follow‐up results from the STAMPEDE randomised trial (NCT00268476)

por James, Nicholas D., Clarke, Noel W., Cook, Adrian, Ali, Adnan, Hoyle, Alex P., Attard, Gerhardt, Brawley, Christopher D., Chowdhury, Simon, Cross, William R., Dearnaley, David P., de Bono, Johann S., Diaz‐Montana, Carlos, Gilbert, Duncan, Gillessen, Silke, Gilson, Clare, Jones, Rob J., Langley, Ruth E., Malik, Zafar I., Matheson, David J., Millman, Robin, Parker, Chris C., Pugh, Cheryl, Rush, Hannah, Russell, J. Martin, Berthold, Dominik R., Buckner, Michelle L., Mason, Malcolm D., Ritchie, Alastair W. S., Birtle, Alison J., Brock, Susannah J., Das, Prantik, Ford, Dan, Gale, Joanna, Grant, Warren, Gray, Emma K., Hoskin, Peter, Khan, Mohammad M., Manetta, Caroline, McPhail, Neil J., O'Sullivan, Joe M., Parikh, Omi, Perna, Carla, Pezaro, Carmel J., Protheroe, Andrew S., Robinson, Angus J., Rudman, Sarah M., Sheehan, Denise J., Srihari, Narayanan N., Syndikus, Isabel, Tanguay, Jacob S., Thomas, Carys W., Vengalil, Salil, Wagstaff, John, Wylie, James P., Parmar, Mahesh K. B., Sydes, Matthew R.
Publicado 2022