The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes

por Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.
Publicado 2023

Malignant Gastrointestinal Neuroectodermal Tumor (GNET) with Prolonged Disease-Free Survival after Platinum-Based Chemotherapy

por Singh, Daulath, Atieh, Mohammed K., Russell, Mark A., Kittaneh, Muaiad
Publicado 2020

Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells

por Russell, Mark A., Cooper, Angela C., Dhayal, Shalinee, Morgan, Noel G.
Publicado 2013

What the HLA-I!—Classical and Non-classical HLA Class I and Their Potential Roles in Type 1 Diabetes

por Wyatt, Rebecca C., Lanzoni, Giacomo, Russell, Mark A., Gerling, Ivan, Richardson, Sarah J.
Publicado 2019

The transcription factor STAT6 plays a critical role in promoting beta cell viability and is depleted in islets of individuals with type 1 diabetes

por Leslie, Kaiyven A., Russell, Mark A., Taniguchi, Kazuto, Richardson, Sarah J., Morgan, Noel G.
Publicado 2018

Temporal regulation of interferon signalling in human EndoC-βH1 cells

por Dhayal, Shalinee, Leslie, Kaiyven Afi, Baity, Mohammad, Akhbari, Pouria, Richardson, Sarah J, Russell, Mark A, Morgan, Noel G
Publicado 2022

Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity

por Bahal, Sameer, Houssen, Maha E., Manson, Ania, Lorenzo, Lorena, Russell, Mark A., Morgan, Noel G., Tahami, Fariba, Grigoriadou, Sofia
Publicado 2019

Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expr...

por King, Renee, Hill, Jessica L., Saha, Bibek, Tong, Yuzhen, Strutt, Brenda J., Russell, Mark A., Morgan, Noel G., Richardson, Sarah J., Hill, David J.
Publicado 2019

Unexpected subcellular distribution of a specific isoform of the Coxsackie and adenovirus receptor, CAR-SIV, in human pancreatic beta cells

por Ifie, Eseoghene, Russell, Mark A., Dhayal, Shalinee, Leete, Pia, Sebastiani, Guido, Nigi, Laura, Dotta, Francesco, Marjomäki, Varpu, Eizirik, Decio L., Morgan, Noel G., Richardson, Sarah J.
Publicado 2018

Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study

por Krogvold, Lars, Leete, Pia, Mynarek, Ida M., Russell, Mark A., Gerling, Ivan C., Lenchik, Nataliya I., Mathews, Clayton, Richardson, Sarah J., Morgan, Noel G., Dahl-Jørgensen, Knut
Publicado 2022

Investigation of the utility of the 1.1B4 cell as a model human beta cell line for study of persistent enteroviral infection

por Chaffey, Jessica R., Young, Jay, Leslie, Kaiyven A., Partridge, Katie, Akhbari, Pouria, Dhayal, Shalinee, Hill, Jessica L., Wedgwood, Kyle C. A., Burnett, Edward, Russell, Mark A., Richardson, Sarah J., Morgan, Noel G.
Publicado 2021

Islet cell hyperexpression of HLA class I antigens: a defining feature in type 1 diabetes

por Richardson, Sarah J., Rodriguez-Calvo, Teresa, Gerling, Ivan C., Mathews, Clayton E., Kaddis, John S., Russell, Mark A., Zeissler, Marie, Leete, Pia, Krogvold, Lars, Dahl-Jørgensen, Knut, von Herrath, Matthias, Pugliese, Alberto, Atkinson, Mark A., Morgan, Noel G.
Publicado 2016

Abnormal islet sphingolipid metabolism in type 1 diabetes

por Holm, Laurits J., Krogvold, Lars, Hasselby, Jane P., Kaur, Simranjeet, Claessens, Laura A., Russell, Mark A., Mathews, Clayton E., Hanssen, Kristian F., Morgan, Noel G., Koeleman, Bobby P. C., Roep, Bart O., Gerling, Ivan C., Pociot, Flemming, Dahl-Jørgensen, Knut, Buschard, Karsten
Publicado 2018

Truncating SLC5A7 mutations underlie a spectrum of dominant hereditary motor neuropathies

por Salter, Claire G., Beijer, Danique, Hardy, Holly, Barwick, Katy E.S., Bower, Matthew, Mademan, Ines, De Jonghe, Peter, Deconinck, Tine, Russell, Mark A., McEntagart, Meriel M., Chioza, Barry A., Blakely, Randy D., Chilton, John K., De Bleecker, Jan, Baets, Jonathan, Baple, Emma L., Walk, David, Crosby, Andrew H.
Publicado 2018

Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease

por Flanagan, Sarah E., Haapaniemi, Emma, Russell, Mark A., Caswell, Richard, Allen, Hana Lango, De Franco, Elisa, McDonald, Timothy J., Rajala, Hanna, Ramelius, Anita, Barton, John, Heiskanen, Kaarina, Heiskanen-Kosma, Tarja, Kajosaari, Merja, Murphy, Nuala P., Milenkovic, Tatjana, Seppänen, Mikko, Lernmark, Åke, Mustjoki, Satu, Otonkoski, Timo, Kere, Juha, Morgan, Noel G., Ellard, Sian, Hattersley, Andrew T.
Publicado 2014

An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells

por Colli, Maikel L., Ramos-Rodríguez, Mireia, Nakayasu, Ernesto S., Alvelos, Maria I., Lopes, Miguel, Hill, Jessica L. E., Turatsinze, Jean-Valery, Coomans de Brachène, Alexandra, Russell, Mark A., Raurell-Vila, Helena, Castela, Angela, Juan-Mateu, Jonàs, Webb-Robertson, Bobbie-Jo M., Krogvold, Lars, Dahl-Jorgensen, Knut, Marselli, Lorella, Marchetti, Piero, Richardson, Sarah J., Morgan, Noel G., Metz, Thomas O., Pasquali, Lorenzo, Eizirik, Décio L.
Publicado 2020