A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol

por Rutten, Lucy, Ribot, Cecile, Trejo-Aguilar, Blanca, Wösten, Han AB, de Vries, Ronald P
Publicado 2009

Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers

por Rutten, Lucy, Gilman, Morgan S.A., Blokland, Sven, Juraszek, Jarek, McLellan, Jason S., Langedijk, Johannes P.M.
Publicado 2020

Neutralisation of HIV-1 cell-cell spread by human and llama antibodies

por McCoy, Laura E, Groppelli, Elisabetta, Blanchetot, Christophe, de Haard, Hans, Verrips, Theo, Rutten, Lucy, Weiss, Robin A, Jolly, Clare
Publicado 2014

Super Potent Bispecific Llama VHH Antibodies Neutralize HIV via a Combination of gp41 and gp120 Epitopes

por Strokappe, Nika M., Hock, Miriam, Rutten, Lucy, Mccoy, Laura E., Back, Jaap W., Caillat, Christophe, Haffke, Matthias, Weiss, Robin A., Weissenhorn, Winfried, Verrips, Theo
Publicado 2019

Stabilizing the closed SARS-CoV-2 spike trimer

por Juraszek, Jarek, Rutten, Lucy, Blokland, Sven, Bouchier, Pascale, Voorzaat, Richard, Ritschel, Tina, Bakkers, Mark J. G., Renault, Ludovic L. R., Langedijk, Johannes P. M.
Publicado 2021

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization

por McCoy, Laura E., Quigley, Anna Forsman, Strokappe, Nika M., Bulmer-Thomas, Bianca, Seaman, Michael S., Mortier, Daniella, Rutten, Lucy, Chander, Nikita, Edwards, Carolyn J., Ketteler, Robin, Davis, David, Verrips, Theo, Weiss, Robin A.
Publicado 2012

Molecular Evolution of Broadly Neutralizing Llama Antibodies to the CD4-Binding Site of HIV-1

por McCoy, Laura E., Rutten, Lucy, Frampton, Dan, Anderson, Ian, Granger, Luke, Bashford-Rogers, Rachael, Dekkers, Gillian, Strokappe, Nika M., Seaman, Michael S., Koh, Willie, Grippo, Vanina, Kliche, Alexander, Verrips, Theo, Kellam, Paul, Fassati, Ariberto, Weiss, Robin A.
Publicado 2014

Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike

por Yu, Xiaodi, Juraszek, Jarek, Rutten, Lucy, Bakkers, Mark J. G., Blokland, Sven, Melchers, Jelle M., van den Broek, Niels J. F., Verwilligen, Annemiek Y. W., Abeywickrema, Pravien, Vingerhoets, Johan, Neefs, Jean-Marc, Bakhash, Shah A. Mohamed, Roychoudhury, Pavitra, Greninger, Alex, Sharma, Sujata, Langedijk, Johannes P. M.
Publicado 2023

A gp41 MPER-specific Llama VHH Requires a Hydrophobic CDR3 for Neutralization but not for Antigen Recognition

por Lutje Hulsik, David, Liu, Ying-ying, Strokappe, Nika M., Battella, Simone, El Khattabi, Mohamed, McCoy, Laura E., Sabin, Charles, Hinz, Andreas, Hock, Miriam, Macheboeuf, Pauline, Bonvin, Alexandre M. J. J., Langedijk, Johannes P. M., Davis, David, Forsman Quigley, Anna, Aasa-Chapman, Marlén M. I., Seaman, Michael S., Ramos, Alejandra, Poignard, Pascal, Favier, Adrien, Simorre, Jean-Pierre, Weiss, Robin A., Verrips, C. Theo, Weissenhorn, Winfried, Rutten, Lucy
Publicado 2013

Ad26 vector-based COVID-19 vaccine encoding a prefusion-stabilized SARS-CoV-2 Spike immunogen induces potent humoral and cellular immune responses

por Bos, Rinke, Rutten, Lucy, van der Lubbe, Joan E. M., Bakkers, Mark J. G., Hardenberg, Gijs, Wegmann, Frank, Zuijdgeest, David, de Wilde, Adriaan H., Koornneef, Annemart, Verwilligen, Annemiek, van Manen, Danielle, Kwaks, Ted, Vogels, Ronald, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., Li, Zhenfeng, Barouch, Dan H., Vellinga, Jort, Langedijk, Johannes P. M., Zahn, Roland C., Custers, Jerome, Schuitemaker, Hanneke
Publicado 2020

Ad26.COV2.S protects Syrian hamsters against G614 spike variant SARS-CoV-2 and does not enhance respiratory disease

por van der Lubbe, Joan E. M., Rosendahl Huber, Sietske K., Vijayan, Aneesh, Dekking, Liesbeth, van Huizen, Ella, Vreugdenhil, Jessica, Choi, Ying, Baert, Miranda R. M., Feddes-de Boer, Karin, Izquierdo Gil, Ana, van Heerden, Marjolein, Dalebout, Tim J., Myeni, Sebenzile K., Kikkert, Marjolein, Snijder, Eric J., de Waal, Leon, Stittelaar, Koert J., Tolboom, Jeroen T. B. M., Serroyen, Jan, Muchene, Leacky, van der Fits, Leslie, Rutten, Lucy, Langedijk, Johannes P. M., Barouch, Dan H., Schuitemaker, Hanneke, Zahn, Roland C., Wegmann, Frank
Publicado 2021

Neutralization Properties of Simian Immunodeficiency Viruses Infecting Chimpanzees and Gorillas

por Barbian, Hannah J., Decker, Julie M., Bibollet-Ruche, Frederic, Galimidi, Rachel P., West, Anthony P., Learn, Gerald H., Parrish, Nicholas F., Iyer, Shilpa S., Li, Yingying, Pace, Craig S., Song, Ruijiang, Huang, Yaoxing, Denny, Thomas N., Mouquet, Hugo, Martin, Loic, Acharya, Priyamvada, Zhang, Baoshan, Kwong, Peter D., Mascola, John R., Verrips, C. Theo, Strokappe, Nika M., Rutten, Lucy, McCoy, Laura E., Weiss, Robin A., Brown, Corrine S., Jackson, Raven, Silvestri, Guido, Connors, Mark, Burton, Dennis R., Shaw, George M., Nussenzweig, Michel C., Bjorkman, Pamela J., Ho, David D., Farzan, Michael, Hahn, Beatrice H.
Publicado 2015

Single-Shot Ad26 Vaccine Protects Against SARS-CoV-2 in Rhesus Macaques

por Mercado, Noe B., Zahn, Roland, Wegmann, Frank, Loos, Carolin, Chandrashekar, Abishek, Yu, Jingyou, Liu, Jinyan, Peter, Lauren, McMahan, Katherine, Tostanoski, Lisa H., He, Xuan, Martinez, David R., Rutten, Lucy, Bos, Rinke, van Manen, Danielle, Vellinga, Jort, Custers, Jerome, Langedijk, Johannes P., Kwaks, Ted, Bakkers, Mark J.G., Zuijdgeest, David, Huber, Sietske K. Rosendahl, Atyeo, Caroline, Fischinger, Stephanie, Burke, John S., Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Bondzie, Esther A., Dagotto, Gabriel, Gebre, Makda S., Hoffman, Emily, Jacob-Dolan, Catherine, Kirilova, Marinela, Li, Zhenfeng, Lin, Zijin, Mahrokhian, Shant H., Maxfield, Lori F., Nampanya, Felix, Nityanandam, Ramya, Nkolola, Joseph P., Patel, Shivani, Ventura, John D., Verrington, Kaylee, Wan, Huahua, Pessaint, Laurent, Van Ry, Alex, Blade, Kelvin, Strasbaugh, Amanda, Cabus, Mehtap, Brown, Renita, Cook, Anthony, Zouantchangadou, Serge, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Cai, Yongfei, Chen, Bing, Schmidt, Aaron G., Reeves, R. Keith, Baric, Ralph S., Lauffenburger, Douglas A., Alter, Galit, Stoffels, Paul, Mammen, Mathai, Van Hoof, Johan, Schuitemaker, Hanneke, Barouch, Dan H.
Publicado 2020