Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells

por Ruvolo, Vivian R., Karanjeet, Kul B., Schuster, Todd F., Brown, Rhoderick, Deng, Yibin, Hinchcliffe, Edward, Ruvolo, Peter P.
Publicado 2010

Low Expression Of PP2A Regulatory Subunit B55α Is Associated With T308 Phosphorylation Of AKT And Shorter Complete Remission Duration In Acute Myeloid Leukemia Patients

por Ruvolo, Peter P., Qui, YiHua, Coombes, Kevin R., Zhang, Nianxiang, Ruvolo, Vivian R., Borthakur, Gautam, Konopleva, Marina, Andreeff, Michael, Kornblau, Steven M.
Publicado 2011

Phosphorylation of GSK3α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients

por Ruvolo, Peter P., Qiu, YiHua, Coombes, Kevin R., Zhang, Nianxiang, Neeley, E. Shannon, Ruvolo, Vivian R., Hail, Numsen, Borthakur, Gautam, Konopleva, Marina, Andreeff, Michael, Kornblau, Steven M.
Publicado 2015

Anexelekto/MER tyrosine kinase inhibitor ONO-7475 arrests growth and kills FMS-like tyrosine kinase 3-internal tandem duplication mutant acute myeloid leukemia cells by diverse mec...

por Ruvolo, Peter P., Ma, Huaxian, Ruvolo, Vivian R., Zhang, Xiaorui, Mu, Hong, Schober, Wendy, Hernandez, Ivonne, Gallardo, Miguel, Khoury, Joseph D., Cortes, Jorge, Andreeff, Michael, Post, Sean M.
Publicado 2017

LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML

por Ruvolo, Peter P., Hu, Chenyue W., Qiu, Yihua, Ruvolo, Vivian R., Go, Robin L., Hubner, Stefan E., Coombes, Kevin R., Andreeff, Michael, Qutub, Amina A., Kornblau, Steven M.
Publicado 2019

Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34(+) proliferating and quiescent chronic myeloid leukemia blast c...

por Carter, Bing Z., Mak, Po Yee, Mak, Duncan H., Ruvolo, Vivian R., Schober, Wendy, McQueen, Teresa, Cortes, Jorge, Kantarjian, Hagop M., Champlin, Richard E., Konopleva, Marina, Andreeff, Michael
Publicado 2015

Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells

por Abrams, Stephen L., Ruvolo, Peter P., Ruvolo, Vivian R., Ligresti, Giovanni, Martelli, Alberto M., Cocco, Lucio, Ratti, Stefano, Tafuri, Agostino, Steelman, Linda S., Candido, Saverio, Libra, Massimo, McCubrey, James A.
Publicado 2017

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

por Kornblau, Steven M., Ruvolo, Peter P., Wang, Rui-Yu, Battula, V. Lokesh, Shpall, Elizabeth J., Ruvolo, Vivian R., McQueen, Teresa, Qui, YiHua, Zeng, Zhihong, Pierce, Sherry, Jacamo, Rodrigo, Yoo, Suk-Young, Le, Phuong M., Sun, Jeffrey, Hail, Numsen, Konopleva, Marina, Andreeff, Michael
Publicado 2018

AXL/MERTK inhibitor ONO-7475 potently synergizes with venetoclax and overcomes venetoclax resistance to kill F LT 3-ITD acute myeloid leukemia

por Post, Sean M., Ma, Huaxian, Malaney, Prerna, Zhang, Xiaorui, Aitken, Marisa J.L., Mak, Po Yee, Ruvolo, Vivian R., Yasuhiro, Tomoko, Kozaki, Ryohei, Chan, Lauren E., Ostermann, Lauren B., Konopleva, Marina, Carter, Bing Z., DiNardo, Courtney, Andreeff, Michael D., Khoury, Joseph D., Ruvolo, Peter P.
Publicado 2021

Enhanced TP53 reactivation disrupts MYC transcriptional program and overcomes venetoclax resistance in acute myeloid leukemias

por Nishida, Yuki, Ishizawa, Jo, Ayoub, Edward, Montoya, Rafael Heinz, Ostermann, Lauren B., Muftuoglu, Muharrem, Ruvolo, Vivian R, Patsilevas, Tallie, Scruggs, Darah A., Khazaei, Shayaun, Mak, Po Yee, Tao, Wenjing, Carter, Bing Z., Boettcher, Steffen, Ebert, Benjamin L., Daver, Naval G., Konopleva, Marina, Seki, Takahiko, Kojima, Kensuke, Andreeff, Michael
Publicado 2023

Concomitant targeting of BCL2 with venetoclax and MAPK signaling with cobimetinib in acute myeloid leukemia models

por Han, Lina, Zhang, Qi, Dail, Monique, Shi, Ce, Cavazos, Antonio, Ruvolo, Vivian R., Zhao, Yang, Kim, Eugene, Rahmani, Mohamed, Mak, Duncan H., Jin, Sha S., Chen, Jun, Phillips, Darren C., Koller, Paul Bottecelli, Jacamo, Rodrigo, Burks, Jared K., DiNardo, Courtney, Daver, Naval, Jabbour, Elias, Wang, Jing, Kantarjian, Hagop M., Andreeff, Michael, Grant, Steven, Leverson, Joel D., Sampath, Deepak, Konopleva, Marina
Publicado 2020

Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

por Zhang, Qi, Riley-Gillis, Bridget, Han, Lina, Jia, Yannan, Lodi, Alessia, Zhang, Haijiao, Ganesan, Saravanan, Pan, Rongqing, Konoplev, Sergej N., Sweeney, Shannon R., Ryan, Jeremy A., Jitkova, Yulia, Dunner, Kenneth, Grosskurth, Shaun E., Vijay, Priyanka, Ghosh, Sujana, Lu, Charles, Ma, Wencai, Kurtz, Stephen, Ruvolo, Vivian R., Ma, Helen, Weng, Connie C., Ramage, Cassandra L., Baran, Natalia, Shi, Ce, Cai, Tianyu, Davis, Richard Eric, Battula, Venkata L., Mi, Yingchang, Wang, Jing, DiNardo, Courtney D., Andreeff, Michael, Tyner, Jeffery W., Schimmer, Aaron, Letai, Anthony, Padua, Rose Ann, Bueso-Ramos, Carlos E., Tiziani, Stefano, Leverson, Joel, Popovic, Relja, Konopleva, Marina
Publicado 2022

Correction: Activation of RAS/MAPK pathway confers MCL-1 mediated acquired resistance to BCL-2 inhibitor venetoclax in acute myeloid leukemia

por Zhang, Qi, Riley-Gillis, Bridget, Han, Lina, Jia, Yannan, Lodi, Alessia, Zhang, Haijiao, Ganesan, Saravanan, Pan, Rongqing, Konoplev, Sergej N., Sweeney, Shannon R., Ryan, Jeremy A., Jitkova, Yulia, Dunner, Kenneth, Grosskurth, Shaun E., Vijay, Priyanka, Ghosh, Sujana, Lu, Charles, Ma, Wencai, Kurtz, Stephen, Ruvolo, Vivian R., Ma, Helen, Weng, Connie C., Ramage, Cassandra L., Baran, Natalia, Shi, Ce, Cai, Tianyu, Davis, Richard Eric, Battula, Venkata L., Mi, Yingchang, Wang, Jing, DiNardo, Courtney D., Andreeff, Michael, Tyner, Jeffery W., Schimmer, Aaron, Letai, Anthony, Padua, Rose Ann, Bueso-Ramos, Carlos E., Tiziani, Stefano, Leverson, Joel, Popovic, Relja, Konopleva, Marina
Publicado 2022