Rho enhancers play unexpectedly minor roles in Rhodopsin transcription and rod cell integrity

por Sun, Chi, Ruzycki, Philip A., Chen, Shiming
Publicado 2023

CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites

por Ruzycki, Philip A., Zhang, Xiaodong, Chen, Shiming
Publicado 2018

A single-cell guide to retinal development: Cell fate decisions of multipotent retinal progenitors in scRNA-seq

por Shiau, Fion, Ruzycki, Philip A., Clark, Brian S.
Publicado 2021

Visionary genomics

por Petrash, J Mark, Ruzycki, Philip A, Zablocki, Gregory J
Publicado 2011

Essential Functions of MLL1 and MLL2 in Retinal Development and Cone Cell Maintenance

por Sun, Chi, Zhang, Xiaodong, Ruzycki, Philip A., Chen, Shiming
Publicado 2022

Mutation of the EPHA2 Tyrosine-Kinase Domain Dysregulates Cell Pattern Formation and Cytoskeletal Gene Expression in the Lens

por Zhou, Yuefang, Bennett, Thomas M., Ruzycki, Philip A., Shiels, Alan
Publicado 2021

Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms

por Zheng, Yiqiao, Sun, Chi, Zhang, Xiaodong, Ruzycki, Philip A, Chen, Shiming
Publicado 2023

Crx-L253X Mutation Produces Dominant Photoreceptor Defects in TVRM65 Mice

por Ruzycki, Philip A., Linne, Courtney D., Hennig, Anne K., Chen, Shiming
Publicado 2017

Missense mutations in CRX homeodomain cause dominant retinopathies through two distinct mechanisms

por Zheng, Yiqiao, Sun, Chi, Zhang, Xiaodong, Ruzycki, Philip A., Chen, Shiming
Publicado 2023

Graded gene expression changes determine phenotype severity in mouse models of CRX-associated retinopathies

por Ruzycki, Philip A., Tran, Nicholas M., Kefalov, Vladimir J., Kolesnikov, Alexander V., Chen, Shiming
Publicado 2015

AMIGO2 Scales Dendrite Arbors in the Retina

por Soto, Florentina, Tien, Nai-Wen, Goel, Anurag, Zhao, Lei, Ruzycki, Philip A., Kerschensteiner, Daniel
Publicado 2019

MLL1 is essential for retinal neurogenesis and horizontal inner neuron integrity

por Brightman, Diana S., Grant, Rachel L., Ruzycki, Philip A., Suzuki, Ray, Hennig, Anne K., Chen, Shiming
Publicado 2018

Aldo-Keto Reductases in the Eye

por Huang, Shun Ping, Palla, Suryanarayana, Ruzycki, Philip, Varma, Ross Arjun, Harter, Theresa, Reddy, G. Bhanuprakesh, Petrash, J. Mark
Publicado 2010

Loss of Mir146b with aging contributes to inflammation and mitochondrial dysfunction in thioglycollate-elicited peritoneal macrophages

por Santeford, Andrea, Lee, Aaron Y, Sene, Abdoulaye, Hassman, Lynn M, Sergushichev, Alexey A, Loginicheva, Ekaterina, Artyomov, Maxim N, Ruzycki, Philip A, Apte, Rajendra S
Publicado 2021

Dry eye disease in mice activates adaptive corneal epithelial regeneration distinct from constitutive renewal in homeostasis

por Lin, Joseph B., Shen, Xiaolei, Pfeifer, Charles W., Shiau, Fion, Santeford, Andrea, Ruzycki, Philip A., Clark, Brian S., Liu, Qin, Huang, Andrew J. W., Apte, Rajendra S.
Publicado 2023

Clinicomolecular Identification of Conserved and Individualized Features of Granulomatous Uveitis

por Hassman, Lynn M., Paley, Michael A., Esaulova, Ekaterina, Paley, Grace L., Ruzycki, Philip A., Linskey, Nicole, Laurent, Jennifer, Feigl-Lenzen, Lacey, Springer, Luke, Montana, Cynthia L., Hong, Karen, Enright, Jennifer, James, Hayley, Artyomov, Maxim N., Yokoyama, Wayne M.
Publicado 2021

Atoh7-independent specification of retinal ganglion cell identity

por Brodie-Kommit, Justin, Clark, Brian S., Shi, Qing, Shiau, Fion, Kim, Dong Won, Langel, Jennifer, Sheely, Catherine, Ruzycki, Philip A, Fries, Michel, Javed, Awais, Cayouette, Michel, Schmidt, Tiffany, Badea, Tudor, Glaser, Tom, Zhao, Haiqing, Singer, Joshua, Blackshaw, Seth, Hattar, Samer
Publicado 2021

Comprehensive identification of mRNA isoforms reveals the diversity of neural cell-surface molecules with roles in retinal development and disease

por Ray, Thomas A., Cochran, Kelly, Kozlowski, Chris, Wang, Jingjing, Alexander, Graham, Cady, Martha A., Spencer, William J., Ruzycki, Philip A., Clark, Brian S., Laeremans, Annelies, He, Ming-Xiao, Wang, Xiaoming, Park, Emily, Hao, Ying, Iannaccone, Alessandro, Hu, Gary, Fedrigo, Olivier, Skiba, Nikolai P., Arshavsky, Vadim Y., Kay, Jeremy N.
Publicado 2020