Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines

por Ryals, Renee C., Boye, Sanford L., Dinculescu, Astra, Hauswirth, William W., Boye, Shannon E.
Publicado 2011

The effects of PEGylation on LNP based mRNA delivery to the eye

por Ryals, Renee C., Patel, Siddharth, Acosta, Chris, McKinney, Madison, Pennesi, Mark E., Sahay, Gaurav
Publicado 2020

An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells

por Surendran, Harshini, Soundararajan, Lalitha, Reddy K, Vijay Bhaskar, Subramani, Janavi, Stoddard, Jonathan, Reynaga, Rene, Tschetter, Wayne, Ryals, Renee C., Pal, Rajarshi
Publicado 2022

Lipid nanoparticles with PEG-variant surface modifications mediate genome editing in the mouse retina

por Gautam, Milan, Jozic, Antony, Su, Grace Li-Na, Herrera-Barrera, Marco, Curtis, Allison, Arrizabalaga, Sebastian, Tschetter, Wayne, Ryals, Renee C., Sahay, Gaurav
Publicado 2023

Long-term Characterization of Retinal Degeneration in Royal College of Surgeons Rats Using Spectral-Domain Optical Coherence Tomography

por Ryals, Renee C., Andrews, Michael D., Datta, Shreya, Coyner, Aaron S., Fischer, Cody M., Wen, Yuquan, Pennesi, Mark E., McGill, Trevor J.
Publicado 2017

The Role of ERK1/2 Activation in Sarpogrelate-Mediated Neuroprotection

por Ku, Cristy A., Ryals, Renee C., Jiang, Dan, Coyner, Aaron S., Weller, Kyle K., Sinha, Wrik, Robb, Bryan M., Yang, Paul, Pennesi, Mark E.
Publicado 2018

Functional and Behavioral Restoration of Vision by Gene Therapy in the Guanylate Cyclase-1 (GC1) Knockout Mouse

por Boye, Shannon E., Boye, Sanford L., Pang, Jijing, Ryals, Renee, Everhart, Drew, Umino, Yumiko, Neeley, Andy W., Besharse, Joseph, Barlow, Robert, Hauswirth, William W.
Publicado 2010

Retinal Neuroprotective Effects of Flibanserin, an FDA-Approved Dual Serotonin Receptor Agonist-Antagonist

por Coyner, Aaron S., Ryals, Renee C., Ku, Cristy A., Fischer, Cody M., Patel, Rachel C., Datta, Shreya, Yang, Paul, Wen, Yuquan, Hen, René, Pennesi, Mark E.
Publicado 2016

A Ketogenic & Low-Protein Diet Slows Retinal Degeneration in rd10 Mice

por Ryals, Renee C., Huang, Samuel J., Wafai, Dahlia, Bernert, Claire, Steele, William, Six, Makayla, Bonthala, Shasank, Titus, Hope, Yang, Paul, Gillingham, Melanie, Pennesi, Mark E.
Publicado 2020

A G1528C Hadha knock-in mouse model recapitulates aspects of human clinical phenotypes for long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency

por Gaston, Garen, Babcock, Shannon, Ryals, Renee, Elizondo, Gabriela, DeVine, Tiffany, Wafai, Dahlia, Packwood, William, Holden, Sarah, Raber, Jacob, Lindner, Jonathan R., Pennesi, Mark E., Harding, Cary O., Gillingham, Melanie B.
Publicado 2023

Spontaneous allelic variant in deafness–blindness gene Ush1g resulting in an expanded phenotype

por Vartanian, Vladimir, Krey, Jocelyn F., Chatterjee, Paroma, Curtis, Allison, Six, Makayla, Rice, Sean P. M., Jones, Sherri M., Sampath, Harini, Allen, Charles N., Ryals, Renee C., Lloyd, R. Stephen, Barr‐Gillespie, Peter G.
Publicado 2023

Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy

por Jiang, Dan, Ryals, Renee C., Huang, Samuel J., Weller, Kyle K., Titus, Hope E., Robb, Bryan M., Saad, Firas W., Salam, Ribal A., Hammad, Hytham, Yang, Paul, Marks, Daniel L., Pennesi, Mark E.
Publicado 2019

Peptide-guided lipid nanoparticles deliver mRNA to the neural retina of rodents and nonhuman primates

por Herrera-Barrera, Marco, Ryals, Renee C., Gautam, Milan, Jozic, Antony, Landry, Madeleine, Korzun, Tetiana, Gupta, Mohit, Acosta, Chris, Stoddard, Jonathan, Reynaga, Rene, Tschetter, Wayne, Jacomino, Nick, Taratula, Oleh, Sun, Conroy, Lauer, Andreas K., Neuringer, Martha, Sahay, Gaurav
Publicado 2023

Natural History of Cone Disease in the Murine Model of Leber Congenital Amaurosis Due to CEP290 Mutation: Determining the Timing and Expectation of Therapy

por Boye, Shannon E., Huang, Wei-Chieh, Roman, Alejandro J., Sumaroka, Alexander, Boye, Sanford L., Ryals, Renee C., Olivares, Melani B., Ruan, Qing, Tucker, Budd A., Stone, Edwin M., Swaroop, Anand, Cideciyan, Artur V., Hauswirth, William W., Jacobson, Samuel G.
Publicado 2014

Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

por Kay, Christine N., Ryals, Renee C., Aslanidi, George V., Min, Seok Hong, Ruan, Qing, Sun, Jingfen, Dyka, Frank M., Kasuga, Daniel, Ayala, Andrea E., Van Vliet, Kim, Agbandje-McKenna, Mavis, Hauswirth, William W., Boye, Sanford L., Boye, Shannon E.
Publicado 2013

Correction: Targeting Photoreceptors via Intravitreal Delivery Using Novel, Capsid-Mutated AAV Vectors

por Kay, Christine N., Ryals, Renee C., Aslanidi, George V., Min, Seok Hong, Ruan, Qing, Sun, Jingfen, Dyka, Frank M., Kasuga, Daniel, Ayala, Andrea E., Van Vliet, Kim, Agbandje-McKenna, Mavis, Hauswirth, William W., Boye, Sanford L., Boye, Shannon E.
Publicado 2013