Membrane lipids from gut microbiome-associated bacteria as structural and signalling molecules

por Ryan, Eileen, Joyce, Susan A., Clarke, David J.
Publicado 2023

Lipidomic Analysis Reveals Differences in Bacteroides Species Driven Largely by Plasmalogens, Glycerophosphoinositols and Certain Sphingolipids

por Ryan, Eileen, Gonzalez Pastor, Belén, Gethings, Lee A., Clarke, David J., Joyce, Susan A.
Publicado 2023

Induced Pluripotent Stem Cells Restore Function in a Human Cell Loss Model of Open-Angle Glaucoma

por Abu-Hassan, Diala W, Li, Xinbo, Ryan, Eileen I, Acott, Ted S, Kelley, Mary J
Publicado 2015

P517: SURVIVAL OUTCOMES WITH CPX-351 VS 7 + 3 BY BASELINE BONE MARROW BLAST PERCENTAGE IN OLDER ADULTS WITH NEWLY DIAGNOSED HIGH-RISK OR SECONDARY ACUTE MYELOID LEUKEMIA: A 5-YEAR...

por Ritchie, Ellen, L. Lin, Tara, F. Newell, Laura, K. Stuart, Robert, Solomon, Scott, Stone, Richard, Schiller, Gary, Wieduwilt, Matthew, Amy Ryan, Eileen, Dronamraju, Nalina, Lancet, Jeffrey, Cortes, Jorge
Publicado 2023

Structural and Biochemical Insights into the Function and Evolution of Sulfoquinovosidases

por Abayakoon, Palika, Jin, Yi, Lingford, James P., Petricevic, Marija, John, Alan, Ryan, Eileen, Wai-Ying Mui, Janice, Pires, Douglas E.V., Ascher, David B., Davies, Gideon J., Goddard-Borger, Ethan D., Williams, Spencer J.
Publicado 2018

Vaccine‐induced immune thrombotic thrombocytopenia (VITT) – a novel clinico‐pathological entity with heterogeneous clinical presentations

por Lavin, Michelle, Elder, Patrick T., O’Keeffe, Denis, Enright, Helen, Ryan, Eileen, Kelly, Anna, El Hassadi, Ezzat, McNicholl, Feargal P., Benson, Gary, Le, Giao N., Byrne, Mary, Ryan, Kevin, O’Connell, Niamh M., O’Donnell, James S.
Publicado 2021

Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo...

por Cioccari, Luca, Luethi, Nora, Duong, Thy, Ryan, Eileen, Cutuli, Salvatore L., Lloyd-Donald, Patryck, Eastwood, Glenn M., Peck, Leah, Young, Helen, Vaara, Suvi T., French, Craig J., Orford, Neil, Dwivedi, Jyotsna, Lankadeva, Yugeesh R., Bailey, Michael, Reid, Gavin E., Bellomo, Rinaldo
Publicado 2023

Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)

por Dong, Yuxiang, Sonawane, Yogesh, Maher, Steven P., Zeeman, Anne-Marie, Chaumeau, Victor, Vantaux, Amélie, Cooper, Caitlin A., Chiu, Francis C. K., Ryan, Eileen, McLaren, Jenna, Chen, Gong, Wittlin, Sergio, Witkowski, Benoît, Nosten, François, Sriraghavan, Kamaraj, Kyle, Dennis E., Kocken, Clemens H. M., Charman, Susan A., Vennerstrom, Jonathan L.
Publicado 2022

Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease

por Keenan, Martine, Chaplin, Jason H., Alexander, Paul W., Abbott, Michael J., Best, Wayne M., Khong, Andrea, Botero, Adriana, Perez, Catherine, Cornwall, Scott, Thompson, R. Andrew, White, Karen L., Shackleford, David M., Koltun, Maria, Chiu, Francis C. K., Morizzi, Julia, Ryan, Eileen, Campbell, Michael, von Geldern, Thomas W., Scandale, Ivan, Chatelain, Eric, Charman, Susan A.
Publicado 2013

An in vitro toolbox to accelerate anti-malarial drug discovery and development

por Charman, Susan A., Andreu, Alice, Barker, Helena, Blundell, Scott, Campbell, Anna, Campbell, Michael, Chen, Gong, Chiu, Francis C. K., Crighton, Elly, Katneni, Kasiram, Morizzi, Julia, Patil, Rahul, Pham, Thao, Ryan, Eileen, Saunders, Jessica, Shackleford, David M., White, Karen L., Almond, Lisa, Dickins, Maurice, Smith, Dennis A., Moehrle, Joerg J., Burrows, Jeremy N., Abla, Nada
Publicado 2020

Discovery, Synthesis, and Optimization of Antimalarial 4(1H)-Quinolone-3-Diarylethers

por Nilsen, Aaron, Miley, Galen P., Forquer, Isaac P., Mather, Michael W., Katneni, Kasiram, Li, Yuexin, Pou, Sovitj, Pershing, April M., Stickles, Allison M., Ryan, Eileen, Kelly, Jane Xu, Doggett, J. Stone, White, Karen L., Hinrichs, David J., Winter, Rolf W., Charman, Susan A., Zakharov, Lev N., Bathurst, Ian, Burrows, Jeremy N., Vaidya, Akhil B., Riscoe, Michael K.
Publicado 2014

Tetrahydro-2-naphthyl and 2-Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity

por Kokkonda, Sreekanth, Deng, Xiaoyi, White, Karen L., Coteron, Jose M., Marco, Maria, de las Heras, Laura, White, John, El Mazouni, Farah, Tomchick, Diana R., Manjalanagara, Krishne, Rudra, Kakali Rani, Chen, Gong, Morizzi, Julia, Ryan, Eileen, Kaminsky, Werner, Leroy, Didier, Martínez-Martínez, María Santos, Jimenez-Diaz, Maria Belen, Bazaga, Santiago Ferrer, Angulo-Barturen, Iñigo, Waterson, David, Burrows, Jeremy N., Matthews, Dave, Charman, Susan A., Phillips, Margaret A., Rathod, Pradipsinh K.
Publicado 2016

Orbital period change of Dimorphos due to the DART kinetic impact

por Thomas, Cristina A., Naidu, Shantanu P., Scheirich, Peter, Moskovitz, Nicholas A., Pravec, Petr, Chesley, Steven R., Rivkin, Andrew S., Osip, David J., Lister, Tim A., Benner, Lance A. M., Brozović, Marina, Contreras, Carlos, Morrell, Nidia, Rożek, Agata, Kušnirák, Peter, Hornoch, Kamil, Mages, Declan, Taylor, Patrick A., Seymour, Andrew D., Snodgrass, Colin, Jørgensen, Uffe G., Dominik, Martin, Skiff, Brian, Polakis, Tom, Knight, Matthew M., Farnham, Tony L., Giorgini, Jon D., Rush, Brian, Bellerose, Julie, Salas, Pedro, Armentrout, William P., Watts, Galen, Busch, Michael W., Chatelain, Joseph, Gomez, Edward, Greenstreet, Sarah, Phillips, Liz, Bonavita, Mariangela, Burgdorf, Martin J., Khalouei, Elahe, Longa-Peña, Penélope, Rabus, Markus, Sajadian, Sedighe, Chabot, Nancy L., Cheng, Andrew F., Ryan, William H., Ryan, Eileen V., Holt, Carrie E., Agrusa, Harrison F.
Publicado 2023

Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles

por Williamson, Alice E., Ylioja, Paul M., Robertson, Murray N., Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B., Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N., Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A., Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L., Delves, Michael, Dennis, Adelaide S. M., Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J., Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P., Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A., Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J., Thomson, Patrick, Turner, Peter, Wallace, Iain M., Wells, Timothy N. C., White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A., Wittlin, Sergio, Todd, Matthew H.
Publicado 2016

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

por O'Neill, Paul M., Amewu, Richard K., Charman, Susan A., Sabbani, Sunil, Gnädig, Nina F., Straimer, Judith, Fidock, David A., Shore, Emma R., Roberts, Natalie L., Wong, Michael H.-L., Hong, W. David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M., Campbell, Simon, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Palmer, Michael J., Copple, Ian M., Mercer, Amy E., Ruecker, Andrea, Delves, Michael J., Sinden, Robert E., Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H. M., Zeeman, Anne-Marie, Nixon, Gemma L., Biagini, Giancarlo A., Ward, Stephen A.
Publicado 2017