Targeting Beta Amyloid: A Clinical Review of Immunotherapeutic Approaches in Alzheimer's Disease

por Lobello, Kasia, Ryan, J. Michael, Liu, Enchi, Rippon, Gregory, Black, Ronald
Publicado 2012

Active immunotherapy options for Alzheimer’s disease

por Winblad, Bengt, Graf, Ana, Riviere, Marie-Emmanuelle, Andreasen, Niels, Ryan, J Michael
Publicado 2014

Trial Designs Likely to Meet Valid Long-Term Alzheimer's Disease Progression Effects: Learning from the Past, Preparing for the Future

por Kemp, Aaron S., Grossberg, George T., Romano, Steven J., Arnold, Douglas L., Ryan, J. Michael, Bullock, Roger, Streiner, David L.
Publicado 2009

A Randomized Trial of Iloperidone for Prevention of Relapse in Schizophrenia: The REPRIEVE Study

por Weiden, Peter J., Manning, Raymond, Wolfgang, Curt D., Ryan, J. Michael, Mancione, Linda, Han, Guangyang, Ahmed, Saeed, Mayo, Mallery G.
Publicado 2016

Rationale for the selection of dual primary endpoints in prevention studies of cognitively unimpaired individuals at genetic risk for developing symptoms of Alzheimer’s disease

por Caputo, Angelika, Racine, Amy, Paule, Ines, Tariot, Pierre N., Langbaum, Jessica B., Coello, Neva, Riviere, Marie-Emmanuelle, Ryan, J. Michael, Lopez, Cristina Lopez, Graf, Ana
Publicado 2023

Active Aβ immunotherapy CAD106 in Alzheimer's disease: A phase 2b study

por Vandenberghe, Rik, Riviere, Marie-Emmanuelle, Caputo, Angelika, Sovago, Judit, Maguire, R. Paul, Farlow, Martin, Marotta, Giovanni, Sanchez-Valle, Raquel, Scheltens, Philip, Ryan, J. Michael, Graf, Ana
Publicado 2016

Long-Term Extensions of Randomized Vaccination Trials of ACC-001 and QS-21 in Mild to Moderate Alzheimer’s Disease

por Hüll, Michael, Sadowsky, Carl, Arai, Heii, Leterme, Ghislaine Le Prince, Holstein, Ann, Booth, Kevin, Peng, Yahong, Yoshiyama, Tamotsu, Suzuki, Hideo, Ketter, Nzeera, Liu, Enchi, Ryan, J. Michael
Publicado 2017

The Alzheimer's Prevention Initiative Generation Program: Study design of two randomized controlled trials for individuals at risk for clinical onset of Alzheimer's disease

por Lopez Lopez, Cristina, Tariot, Pierre N., Caputo, Angelika, Langbaum, Jessica B., Liu, Fonda, Riviere, Marie-Emmanuelle, Langlois, Carolyn, Rouzade-Dominguez, Marie-Laure, Zalesak, Martin, Hendrix, Suzanne, Thomas, Ronald G., Viglietta, Vissia, Lenz, Rob, Ryan, J. Michael, Graf, Ana, Reiman, Eric M.
Publicado 2019

Building clinically relevant outcomes across the Alzheimer's disease spectrum

por Rentz, Dorene M., Wessels, Alette M., Annapragada, Ananth V., Berger, Anna‐Karin, Edgar, Chris J., Gold, Michael, Miller, David S., Randolph, Christopher, Ryan, J. Michael, Wunderlich, Glen, Zoschg, Megan Canniere, Trépel, Dominic, Knopman, David S., Staffaroni, Adam M., Bain, Lisa J., Carrillo, Maria C., Weber, Christopher J.
Publicado 2021

In vivo tau pathology is associated with synaptic loss and altered synaptic function

por Coomans, Emma M., Schoonhoven, Deborah N., Tuncel, Hayel, Verfaillie, Sander C. J., Wolters, Emma E., Boellaard, Ronald, Ossenkoppele, Rik, den Braber, Anouk, Scheper, Wiep, Schober, Patrick, Sweeney, Steven P., Ryan, J. Michael, Schuit, Robert C., Windhorst, Albert D., Barkhof, Frederik, Scheltens, Philip, Golla, Sandeep S. V., Hillebrand, Arjan, Gouw, Alida A., van Berckel, Bart N. M.
Publicado 2021

Kinetics and 28-day test–retest repeatability and reproducibility of [(11)C]UCB-J PET brain imaging

por Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M, de Vries, Erik FJ, Glaudemans, Andor WJM, Feltes, Paula Kopschina, García, David V, Verfaillie, Sander CJ, Wolters, Emma E, Sweeney, Steven P, Ryan, J Michael, Ivarsson, Magnus, Lynch, Berkley A, Schober, Patrick, Scheltens, Philip, Schuit, Robert C, Windhorst, Albert D, De Deyn, Peter P, van Berckel, Bart NM, Golla, Sandeep SV
Publicado 2020

Value-Generating Exploratory Trials in Neurodegenerative Dementias

por Friedman, Lauren G., McKeehan, Nicholas, Hara, Yuko, Cummings, Jeffrey L., Matthews, Dawn C., Zhu, Jian, Mohs, Richard C., Wang, Deli, Hendrix, Suzanne B., Quintana, Melanie, Schneider, Lon S., Grundman, Michael, Dickson, Samuel P., Feldman, Howard H., Jaeger, Judith, Finger, Elizabeth C., Ryan, J. Michael, Niehoff, Debra, Dickinson, Susan L-J., Markowitz, Jessica T., Owen, Meriel, Travaglia, Alessio, Fillit, Howard M.
Publicado 2021

Validation and test–retest repeatability performance of parametric methods for [(11)C]UCB-J PET

por Tuncel, Hayel, Boellaard, Ronald, Coomans, Emma M., Hollander-Meeuwsen, Marijke den, de Vries, Erik F. J., Glaudemans, Andor W. J. M., Feltes, Paula Kopschina, García, David Vállez, Verfaillie, Sander C. J., Wolters, Emma E., Sweeney, Steven P., Ryan, J. Michael, Ivarsson, Magnus, Lynch, Berkley A., Schober, Patrick, Scheltens, Philip, Schuit, Robert C., Windhorst, Albert D., De Deyn, Peter P., van Berckel, Bart N. M., Golla, Sandeep S. V.
Publicado 2022