Regulation of Glutamate, GABA and Dopamine Transporter Uptake, Surface Mobility and Expression

por Ryan, Renae M., Ingram, Susan L., Scimemi, Annalisa
Publicado 2021

Characterizing unexpected interactions of a glutamine transporter inhibitor with members of the SLC1A transporter family

por Freidman, Natasha J., Briot, Chelsea, Ryan, Renae M.
Publicado 2022

Tuning the ion selectivity of glutamate transporter–associated uncoupled conductances

por Cater, Rosemary J., Vandenberg, Robert J., Ryan, Renae M.
Publicado 2016

Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5

por Scopelliti, Amanda J, Font, Josep, Vandenberg, Robert J, Boudker, Olga, Ryan, Renae M
Publicado 2018

Position of the Third Na(+) Site in the Aspartate Transporter Glt(Ph) and the Human Glutamate Transporter, EAAT1

por Bastug, Turgut, Heinzelmann, Germano, Kuyucak, Serdar, Salim, Marietta, Vandenberg, Robert J., Ryan, Renae M.
Publicado 2012

Identification of a 3(rd) Na(+) Binding Site of the Glycine Transporter, GlyT2

por Subramanian, Nandhitha, Scopelitti, Amanda J., Carland, Jane E., Ryan, Renae M., O’Mara, Megan L., Vandenberg, Robert J.
Publicado 2016

Correction: Identification of a 3(rd) Na(+) Binding Site of the Glycine Transporter, GlyT2

por Subramanian, Nandhitha, Scopelliti, Amanda J., Carland, Jane E., Ryan, Renae M., O’Mara, Megan L., Vandenberg, Robert J.
Publicado 2016

Glutamate transporters have a chloride channel with two hydrophobic gates

por Chen, Ichia, Pant, Shashank, Wu, Qianyi, Cater, Rosemary, Sobti, Meghna, Vandenberg, Robert, Stewart, Alastair G., Tajkhorshid, Emad, Font, Josep, Ryan, Renae
Publicado 2021

Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK

por Vinh, Natalie B, Devine, Shane M, Munoz, Lenka, Ryan, Renae M, Wang, Bing H, Krum, Henry, Chalmers, David K, Simpson, Jamie S, Scammells, Peter J
Publicado 2015

Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways

por van Geldermalsen, Michelle, Quek, Lake-Ee, Turner, Nigel, Freidman, Natasha, Pang, Angel, Guan, Yi Fang, Krycer, James R., Ryan, Renae, Wang, Qian, Holst, Jeff
Publicado 2018

Ataxia-linked SLC1A3 mutations alter EAAT1 chloride channel activity and glial regulation of CNS function

por Wu, Qianyi, Akhter, Azman, Pant, Shashank, Cho, Eunjoo, Zhu, Jin Xin, Garner, Alastair, Ohyama, Tomoko, Tajkhorshid, Emad, van Meyel, Donald J., Ryan, Renae M.
Publicado 2022

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

por Mostyn, Shannon N, Wilson, Katie A, Schumann-Gillett, Alexandra, Frangos, Zachary J, Shimmon, Susan, Rawling, Tristan, Ryan, Renae M, O'Mara, Megan L, Vandenberg, Robert J
Publicado 2019

Structural basis of promiscuous substrate transport by Organic Cation Transporter 1

por Zeng, Yi C., Sobti, Meghna, Quinn, Ada, Smith, Nicola J., Brown, Simon H. J., Vandenberg, Jamie I., Ryan, Renae M., O’Mara, Megan L., Stewart, Alastair G.
Publicado 2023

Monoterpene Glycoside ESK246 from Pittosporum Targets LAT3 Amino Acid Transport and Prostate Cancer Cell Growth

por Wang, Qian, Grkovic, Tanja, Font, Josep, Bonham, Sarah, Pouwer, Rebecca H, Bailey, Charles G, Moran, Anne M, Ryan, Renae M, Rasko, John EJ, Jormakka, Mika, Quinn, Ronald J, Holst, Jeff
Publicado 2014

Psychomotor impairments and therapeutic implications revealed by a mutation associated with infantile Parkinsonism-Dystonia

por Aguilar, Jenny I, Cheng, Mary Hongying, Font, Josep, Schwartz, Alexandra C, Ledwitch, Kaitlyn, Duran, Amanda, Mabry, Samuel J, Belovich, Andrea N, Zhu, Yanqi, Carter, Angela M, Shi, Lei, Kurian, Manju A, Fenollar-Ferrer, Cristina, Meiler, Jens, Ryan, Renae Monique, Mchaourab, Hassane S, Bahar, Ivet, Matthies, Heinrich JG, Galli, Aurelio
Publicado 2021