A phase I clinical trial of avelumab in combination with decitabine as first line treatment of unfit patients with acute myeloid leukemia

por Zheng, Hong, Mineishi, Shin, Claxton, David, Zhu, Junjia, Zhao, Chenchen, Jia, Bei, Ehmann, W. Christopher, Rybka, Witold B., Naik, Seema, Songdej, Natthapol, Drabick, Joseph J., Hohl, Raymond J.
Publicado 2020

Bone marrow CD8 T cells express high frequency of PD-1 and exhibit reduced anti-leukemia response in newly diagnosed AML patients

por Jia, Bei, Wang, Liru, Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Rizvi, Syed, Shike, Hiroko, Bayerl, Michael, Schell, Todd D., Hohl, Raymond J., Zheng, Hong
Publicado 2018

VISTA is highly expressed on MDSCs and mediates an inhibition of T cell response in patients with AML

por Wang, Liru, Jia, Bei, Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Naik, Seema, Khawaja, Muhammad R., Sivik, Jeff, Han, Junyan, Hohl, Raymond J., Zheng, Hong
Publicado 2018

Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia

por Zhu, Liuluan, Kong, Yaxian, Zhang, Jianhong, Claxton, David F., Ehmann, W. Christopher, Rybka, Witold B., Palmisiano, Neil D., Wang, Ming, Jia, Bei, Bayerl, Michael, Schell, Todd D., Hohl, Raymond J., Zeng, Hui, Zheng, Hong
Publicado 2017

Multi‐dimensional analysis identifies an immune signature predicting response to decitabine treatment in elderly patients with AML

por Zhao, Chenchen, Jia, Bei, Wang, Ming, Schell, Todd D., Claxton, David F., Ehmann, W Christopher, Rybka, Witold B., Mineishi, Shin, Naik, Seema, Songdej, Natthapol, Sivik, Jeff M., Hohl, Raymond J., Zeng, Hui, Zheng, Hong
Publicado 2019

Post-transplant cyclophosphamide alters immune signatures and leads to impaired T cell reconstitution in allogeneic hematopoietic stem cell transplant

por Zhao, Chenchen, Bartock, Matthew, Jia, Bei, Shah, Neal, Claxton, David F., Wirk, Baldeep, Rakszawski, Kevin L., Nickolich, Myles S., Naik, Seema G., Rybka, Witold B., Ehmann, W Christopher C., Hohl, Raymond J., Valentin, Jessica, Bernas-Peterson, Michelle, Gerber, Emily M., Zimmerman, Michele, Mierski, Joseph A., Mineishi, Shin, Zheng, Hong
Publicado 2022

PIGN gene expression aberration is associated with genomic instability and leukemic progression in acute myeloid leukemia with myelodysplastic features

por Teye, Emmanuel K., Sido, Abigail, Xin, Ping, Finnberg, Niklas K., Gokare, Prashanth, Kawasawa, Yuka I., Salzberg, Anna C., Shimko, Sara, Bayerl, Michael, Ehmann, W. Christopher, Claxton, David F., Rybka, Witold B., Drabick, Joseph J., Wang, Hong-Gang, Abraham, Thomas, El-Deiry, Wafik S., Brodsky, Robert A., Hohl, Raymond J., Pu, Jeffrey J.
Publicado 2017

Related peripheral blood stem cell donors experience more severe symptoms and less complete recovery at one year compared to unrelated donors

por Pulsipher, Michael A., Logan, Brent R., Kiefer, Deidre M., Chitphakdithai, Pintip, Riches, Marcie L., Rizzo, J. Douglas, Anderlini, Paolo, Leitman, O’Susan F., Kobusingye, Hati, Besser, RaeAnne M., Miller, John P., Drexler, Rebecca J., Abdel-Mageed, Aly, Ahmed, Ibrahim A., Akard, Luke P., Artz, Andrew S., Ball, Edward D., Bayer, Ruthee-Lu, Bigelow, Carolyn, Bolwell, Brian J., Broun, E. Randolph, Delgado, David C., Duckworth, Katharine, Dvorak, Christopher C., Hahn, Theresa E., Haight, Ann E., Hari, Parameswaran N., Hayes-Lattin, Brandon M., Jacobsohn, David A., Jakubowski, Ann A., Kasow, Kimberly A., Lazarus, Hillard M., Liesveld, Jane L., Linenberger, Michael, Litzow, Mark R., Longo, Walter, Magalhaes-Silverman, Margarida, McCarty, John M., McGuirk, Joseph P., Mori, Shahram, Parameswaran, Vinod, Prasad, Vinod K., Rowley, Scott D., Rybka, Witold B., Sahdev, Indira, Schriber, Jeffrey R., Selby, George B., Shaughnessy, Paul J., Shenoy, Shalini, Spitzer, Thomas, Tse, William T., Uberti, Joseph P., Vusirikala, Madhuri, Waller, Edmund K., Weisdorf, Daniel J., Yanik, Gregory A., Navarro, Willis H., Horowitz, Mary M., Switzer, Galen E., Confer, Dennis L., Shaw, Bronwen E.
Publicado 2019