The ageing neuromuscular system and sarcopenia: a mitochondrial perspective

por Rygiel, Karolina A., Picard, Martin, Turnbull, Doug M.
Publicado 2016

Respiratory chain deficiency in aged spinal motor neurons()

por Rygiel, Karolina A., Grady, John P., Turnbull, Doug M.
Publicado 2014

Triplex real-time PCR–an improved method to detect a wide spectrum of mitochondrial DNA deletions in single cells

por Rygiel, Karolina A., Grady, John P., Taylor, Robert W., Tuppen, Helen A. L., Turnbull, Doug M.
Publicado 2015

Mitochondrial DNA Depletion in Respiratory Chain–Deficient Parkinson Disease Neurons

por Grünewald, Anne, Rygiel, Karolina A., Hepplewhite, Philippa D., Morris, Christopher M., Picard, Martin, Turnbull, Doug M.
Publicado 2016

Polyfunctional response by ImmTAC (IMCgp100) redirected CD8(+) and CD4(+) T cells

por Boudousquie, Caroline, Bossi, Giovanna, Hurst, Jacob M., Rygiel, Karolina A., Jakobsen, Bent K., Hassan, Namir J.
Publicado 2017

Denervation Causes Fiber Atrophy and Myosin Heavy Chain Co-Expression in Senescent Skeletal Muscle

por Rowan, Sharon L., Rygiel, Karolina, Purves-Smith, Fennigje M., Solbak, Nathan M., Turnbull, Douglas M., Hepple, Russell T.
Publicado 2012

Mitochondrial and inflammatory changes in sporadic inclusion body myositis

por Rygiel, Karolina A., Miller, James, Grady, John P., Rocha, Mariana C., Taylor, Robert W., Turnbull, Doug M.
Publicado 2015

Naked mole-rats maintain healthy skeletal muscle and Complex IV mitochondrial enzyme function into old age

por Stoll, Elizabeth A, Karapavlovic, Nevena, Rosa, Hannah, Woodmass, Michael, Rygiel, Karolina, White, Kathryn, Turnbull, Douglass M, Faulkes, Chris G
Publicado 2016

A novel immunofluorescent assay to investigate oxidative phosphorylation deficiency in mitochondrial myopathy: understanding mechanisms and improving diagnosis

por Rocha, Mariana C., Grady, John P., Grünewald, Anne, Vincent, Amy, Dobson, Philip F., Taylor, Robert W., Turnbull, Doug M., Rygiel, Karolina A.
Publicado 2015

Quantitative quadruple-label immunofluorescence of mitochondrial and cytoplasmic proteins in single neurons from human midbrain tissue

por Grünewald, Anne, Lax, Nichola Z., Rocha, Mariana C., Reeve, Amy K., Hepplewhite, Philippa D., A. Rygiel, Karolina, Taylor, Robert W., Turnbull, Doug M.
Publicado 2014

Mitochondrial dysfunction in myofibrillar myopathy

por Vincent, Amy E., Grady, John P., Rocha, Mariana C., Alston, Charlotte L., Rygiel, Karolina A., Barresi, Rita, Taylor, Robert W., Turnbull, Doug M.
Publicado 2016

Dysferlin mutations and mitochondrial dysfunction

por Vincent, Amy E., Rosa, Hannah S., Alston, Charlotte L., Grady, John P., Rygiel, Karolina A., Rocha, Mariana C., Barresi, Rita, Taylor, Robert W., Turnbull, Doug M.
Publicado 2016

Complex mitochondrial DNA rearrangements in individual cells from patients with sporadic inclusion body myositis

por Rygiel, Karolina A., Tuppen, Helen A., Grady, John P., Vincent, Amy, Blakely, Emma L., Reeve, Amy K., Taylor, Robert W., Picard, Martin, Miller, James, Turnbull, Doug M.
Publicado 2016

Skeletal muscle mitochondrial oxidative phosphorylation function in idiopathic pulmonary arterial hypertension: in vivo and in vitro study

por Sithamparanathan, Sasiharan, Rocha, Mariana C., Parikh, Jehill D., Rygiel, Karolina A., Falkous, Gavin, Grady, John P., Hollingsworth, Kieren G., Trenell, Michael I., Taylor, Robert W., Turnbull, Doug M., Gorman, Gráinne S., Corris, Paul A.
Publicado 2018

Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo

por Russell, Oliver M., Fruh, Isabelle, Rai, Pavandeep K., Marcellin, David, Doll, Thierry, Reeve, Amy, Germain, Mitchel, Bastien, Julie, Rygiel, Karolina A., Cerino, Raffaele, Sailer, Andreas W., Lako, Majlinda, Taylor, Robert W., Mueller, Matthias, Lightowlers, Robert N., Turnbull, Doug M., Helliwell, Stephen B.
Publicado 2018

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle

por Vincent, Amy E., Rosa, Hannah S., Pabis, Kamil, Lawless, Conor, Chen, Chun, Grünewald, Anne, Rygiel, Karolina A., Rocha, Mariana C., Reeve, Amy K., Falkous, Gavin, Perissi, Valentina, White, Kathryn, Davey, Tracey, Petrof, Basil J., Sayer, Avan A., Cooper, Cyrus, Deehan, David, Taylor, Robert W., Turnbull, Doug M., Picard, Martin
Publicado 2018

Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM

por Bashore, Frances M., Katis, Vittorio L., Du, Yuhong, Sikdar, Arunima, Wang, Dongxue, Bradshaw, William J., Rygiel, Karolina A., Leisner, Tina M., Chalk, Rod, Mishra, Swati, Williams, Andrew C., Gileadi, Opher, Brennan, Paul E., Wiley, Jesse C., Gockley, Jake, Cary, Gregory A., Carter, Gregory W., Young, Jessica E., Pearce, Kenneth H., Fu, Haian, Axtman, Alison D.
Publicado 2023

An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules

por Harper, Jane, Adams, Katherine J., Bossi, Giovanna, Wright, Debbie E., Stacey, Andrea R., Bedke, Nicole, Martinez-Hague, Ruth, Blat, Dan, Humbert, Laure, Buchanan, Hazel, Le Provost, Gabrielle S., Donnellan, Zoe, Carreira, Ricardo J., Paston, Samantha J., Weigand, Luise U., Canestraro, Martina, Sanderson, Joseph P., Botta Gordon-Smith, Sophie, Lowe, Kate L., Rygiel, Karolina A., Powlesland, Alex S., Vuidepot, Annelise, Hassan, Namir J., Cameron, Brian J., Jakobsen, Bent K., Dukes, Joseph
Publicado 2018