Alleviation of depression-like behavior in a cystic fibrosis mouse model by Hdac6 depletion

por Corey, Deborah A., Rymut, Sharon M., Kelley, Thomas J.
Publicado 2020

Improved Growth Patterns in Cystic Fibrosis Mice after Loss of Histone Deacetylase 6

por Rymut, Sharon M., Corey, Deborah A., Valerio, Dana M., Erokwu, Bernadette O., Flask, Chris A., Kelley, Thomas J., Hodges, Craig A.
Publicado 2017

1305. Comparison of Pharmacokinetics of DSTA4637S, a novel THIOMAB(TM) Antibody-Antibiotic Conjugate, in Patients with Staphylococcus aureus Bacteremia Receiving Standard-of-Care A...

por Rymut, Sharon M, Deng, Rong, Owen, Ryan, Saad, Ola, Berhanu, Aklile, Lim, Jeremy, Carrasco-Triguero, Montserrat, Couch, Jessica A, Peck, Melicent C
Publicado 2020

A mechanistic PK/PD model to enable dose selection of the potent anti‐tryptase antibody (MTPS9579A) in patients with moderate‐to‐severe asthma

por Rymut, Sharon M., Henderson, Lindsay M., Poon, Victor, Staton, Tracy L., Cai, Fang, Sukumaran, Siddharth, Rhee, Horace, Owen, Ryan, Ramanujan, Saroja, Yoshida, Kenta
Publicado 2023

167. A Phase 1b, Randomized, Double-blind, Placebo-controlled, Multiple-ascending Dose Study to Investigate the Safety, Tolerability, and Pharmacokinetics of DSTA4637S in Patients...

por Lim, Jeremy, Lewin-Koh, Nicholas, Chu, Tom, Rymut, Sharon M, Berhanu, Aklile, Carrasco-Triguero, Montserrat, Rosenberger, Carrie C, Hazenbos, Wouter L, Miller, Loren G, Fowler, Vance G, Miro, Jose M, Couch, Jessica A, Peck, Melicent C
Publicado 2020

Dose‐dependent inactivation of airway tryptase with a novel dissociating anti‐tryptase antibody (MTPS9579A) in healthy participants: A randomized trial

por Rymut, Sharon M., Sukumaran, Siddharth, Sperinde, Gizette, Bremer, Meire, Galanter, Joshua, Yoshida, Kenta, Smith, Jordan, Banerjee, Prajna, Sverkos, Viyia, Cai, Fang, Steffen, Verena, Henderson, Lindsay M., Rhee, Horace, Belloni, Paula N., Lin, Joseph H., Staton, Tracy L.
Publicado 2021