Targeted sequencing of the 9p21.3 region reveals association with reduced disease risks in Ashkenazi Jewish centenarians

por Zhu, Yizhou, Ryu, Seungjin, Tare, Archana, Barzilai, Nir, Atzmon, Gil, Suh, Yousin
Publicado 2023

High-throughput sequencing analysis of nuclear-encoded mitochondrial genes reveals a genetic signature of human longevity

por Gonzalez, Brenda, Tare, Archana, Ryu, Seungjin, Johnson, Simon C., Atzmon, Gil, Barzilai, Nir, Kaeberlein, Matt, Suh, Yousin
Publicado 2022

Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity

por Ravussin, Anthony, Youm, Yun-Hee, Sander, Jil, Ryu, Seungjin, Nguyen, Kim, Varela, Luis, Suhlman, Gerald I., Sidorov, Sviatoslav, Horvath, Tamas L., Schultze, Joachim L., Dixit, Vishwa Deep
Publicado 2018

Reduction of SPARC protects mice against NLRP3 inflammasome activation and obesity

por Ryu, Seungjin, Spadaro, Olga, Sidorov, Sviatoslav, Lee, Aileen H., Caprio, Sonia, Morrison, Christopher, Smith, Steven R., Ravussin, Eric, Shchukina, Irina, Artyomov, Maxim N., Youm, Yun-Hee, Dixit, Vishwa Deep
Publicado 2023

Genetic signature of human longevity in PKC and NF‐κB signaling

por Ryu, Seungjin, Han, Jeehae, Norden‐Krichmar, Trina M., Zhang, Quanwei, Lee, Seunggeun, Zhang, Zhengdong, Atzmon, Gil, Niedernhofer, Laura J., Robbins, Paul D., Barzilai, Nir, Schork, Nicholas J., Suh, Yousin
Publicado 2021

Ketogenic diet restrains aging-induced exacerbation of coronavirus infection in mice

por Ryu, Seungjin, Shchukina, Irina, Youm, Yun-Hee, Qing, Hua, Hilliard, Brandon, Dlugos, Tamara, Zhang, Xinbo, Yasumoto, Yuki, Booth, Carmen J, Fernández-Hernando, Carlos, Suárez, Yajaira, Khanna, Kamal, Horvath, Tamas L, Dietrich, Marcelo O, Artyomov, Maxim, Wang, Andrew, Dixit, Vishwa Deep
Publicado 2021

A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A

por Simon, Matthew, Yang, Jiping, Gigas, Jonathan, Earley, Eric J, Hillpot, Eric, Zhang, Lei, Zagorulya, Maria, Tombline, Greg, Gilbert, Michael, Yuen, Samantha L, Pope, Alexis, Van Meter, Michael, Emmrich, Stephan, Firsanov, Denis, Athreya, Advait, Biashad, Seyed Ali, Han, Jeehae, Ryu, Seungjin, Tare, Archana, Zhu, Yizhou, Hudgins, Adam, Atzmon, Gil, Barzilai, Nir, Wolfe, Aaron, Moody, Kelsey, Garcia, Benjamin A, Thomas, David D, Robbins, Paul D, Vijg, Jan, Seluanov, Andrei, Suh, Yousin, Gorbunova, Vera
Publicado 2022