Biased and Unbiased Methods for the Detection of Off-Target Cleavage by CRISPR/Cas9: An Overview

por Martin, Francisco, Sánchez-Hernández, Sabina, Gutiérrez-Guerrero, Alejandra, Pinedo-Gomez, Javier, Benabdellah, Karim
Publicado 2016

LRRK2 Knockout Confers Resistance in HEK-293 Cells to Rotenone-Induced Oxidative Stress, Mitochondrial Damage, and Apoptosis

por Quintero-Espinosa, Diana Alejandra, Sanchez-Hernandez, Sabina, Velez-Pardo, Carlos, Martin, Francisco, Jimenez-Del-Rio, Marlene
Publicado 2023

Lent-On-Plus Lentiviral vectors for conditional expression in human stem cells

por Benabdellah, Karim, Muñoz, Pilar, Cobo, Marién, Gutierrez-Guerrero, Alejandra, Sánchez-Hernández, Sabina, Garcia-Perez, Angélica, Anderson, Per, Carrillo-Gálvez, Ana Belén, Toscano, Miguel G., Martin, Francisco
Publicado 2016

Development of Cellular Models to Study Efficiency and Safety of Gene Edition by Homologous Directed Recombination Using the CRISPR/Cas9 System

por Sánchez-Hernández, Sabina, Aguilar-González, Araceli, Guijarro-Albaladejo, Beatriz, Maldonado-Pérez, Noelia, Ramos-Hernández, Iris, Cortijo-Gutiérrez, Marina, Sánchez Martín, Rosario María, Benabdellah, Karim, Martin, Francisco
Publicado 2020

Using Gene Editing Approaches to Fine-Tune the Immune System

por Pavlovic, Kristina, Tristán-Manzano, María, Maldonado-Pérez, Noelia, Cortijo-Gutierrez, Marina, Sánchez-Hernández, Sabina, Justicia-Lirio, Pedro, Carmona, M. Dolores, Herrera, Concha, Martin, Francisco, Benabdellah, Karim
Publicado 2020

Improved Functionality of Integration-Deficient Lentiviral Vectors (IDLVs) by the Inclusion of IS(2) Protein Docks

por Cortijo-Gutiérrez, Marina, Sánchez-Hernández, Sabina, Tristán-Manzano, María, Maldonado-Pérez, Noelia, Lopez-Onieva, Lourdes, Real, Pedro J., Herrera, Concha, Marchal, Juan Antonio, Martin, Francisco, Benabdellah, Karim
Publicado 2021

Genome‐edited adult stem cells: Next‐generation advanced therapy medicinal products

por Benabdellah, Karim, Sánchez‐Hernández, Sabina, Aguilar‐González, Araceli, Maldonado‐Pérez, Noelia, Gutierrez‐Guerrero, Alejandra, Cortijo‐Gutierrez, Marina, Ramos‐Hernández, Iris, Tristán‐Manzano, María, Galindo‐Moreno, Pablo, Herrera, Concha, Martin, Francisco
Publicado 2020

Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism

por González-García, Pilar, Hidalgo-Gutiérrez, Agustín, Mascaraque, Cristina, Barriocanal-Casado, Eliana, Bakkali, Mohammed, Ziosi, Marcello, Abdihankyzy, Ussipbek Botagoz, Sánchez-Hernández, Sabina, Escames, Germaine, Prokisch, Holger, Martín, Francisco, Quinzii, Catarina M, López, Luis C
Publicado 2020

Rnd3 Expression is Necessary to Maintain Mitochondrial Homeostasis but Dispensable for Autophagy

por Cueto-Ureña, Cristina, Mocholí, Enric, Escrivá-Fernández, Josep, González-Granero, Susana, Sánchez-Hernández, Sabina, Solana-Orts, Amalia, Ballester-Lurbe, Begoña, Benabdellah, Karim, Guasch, Rosa M., García-Verdugo, José Manuel, Martín, Francisco, Coffer, Paul J., Pérez-Roger, Ignacio, Poch, Enric
Publicado 2022

The IS2 Element Improves Transcription Efficiency of Integration-Deficient Lentiviral Vector Episomes

por Sánchez-Hernández, Sabina, Gutierrez-Guerrero, Alejandra, Martín-Guerra, Rocío, Cortijo-Gutierrez, Marina, Tristán-Manzano, María, Rodriguez-Perales, Sandra, Sanchez, Laura, Garcia-Perez, Jose Luis, Chato-Astrain, Jesus, Fernandez-Valades, Ricardo, Carrillo-Galvez, Ana Belén, Anderson, Per, Montes, Rosa, Real, Pedro J., Martin, Francisco, Benabdellah, Karim
Publicado 2018

Physiological lentiviral vectors for the generation of improved CAR-T cells

por Tristán-Manzano, María, Maldonado-Pérez, Noelia, Justicia-Lirio, Pedro, Muñoz, Pilar, Cortijo-Gutiérrez, Marina, Pavlovic, Kristina, Jiménez-Moreno, Rosario, Nogueras, Sonia, Carmona, M. Dolores, Sánchez-Hernández, Sabina, Aguilar-González, Araceli, Castella, María, Juan, Manel, Marañón, Concepción, Marchal, Juan Antonio, Benabdellah, Karim, Herrera, Concha, Martin, Francisco
Publicado 2022

Physiological lentiviral vectors for the generation of improved CAR-T cells

por Tristán-Manzano, María, Maldonado-Pérez, Noelia, Justicia-Lirio, Pedro, Muñoz, Pilar, Cortijo-Gutiérrez, Marina, Pavlovic, Kristina, Jiménez-Moreno, Rosario, Nogueras, Sonia, Carmona, M. Dolores, Sánchez-Hernández, Sabina, Aguilar-González, Araceli, Castella, María, Juan, Manel, Marañón, Concepción, Marchal, Juan Antonio, Benabdellah, Karim, Herrera, Concha, Martin, Francisco
Publicado 2022

GARP promotes the proliferation and therapeutic resistance of bone sarcoma cancer cells through the activation of TGF-β

por Carrillo-Gálvez, Ana Belén, Quintero, Juan Esteban, Rodríguez, René, Menéndez, Sofía T., Victoria González, M., Blanco-Lorenzo, Verónica, Allonca, Eva, de Araújo Farias, Virgínea, González-Correa, Juan Elías, Erill-Sagalés, Nadina, Martínez-Zubiaurre, Iñigo, Hellevik, Turid, Sánchez-Hernández, Sabina, Muñoz, Pilar, Zurita, Federico, Martín, Francisco, Rodríguez-Manzaneque, Juan Carlos, Anderson, Per
Publicado 2020