Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives

por Xu, Jia, Yang, Pengwei, Xue, Shang, Sharma, Bhuvan, Sanchez-Martin, Marta, Wang, Fang, Beaty, Kirk A., Dehan, Elinor, Parikh, Baiju
Publicado 2019

Leukemia-specific delivery of mutant NOTCH1 targeted therapy

por Roti, Giovanni, Qi, Jun, Kitara, Samuel, Sanchez-Martin, Marta, Saur Conway, Amy, Varca, Anthony C., Su, Angela, Wu, Lei, Kung, Andrew L., Ferrando, Adolfo A., Bradner, James E., Stegmaier, Kimberly
Publicado 2018

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in acute lymphoblastic leukemia

por Herranz, Daniel, Ambesi-Impiombato, Alberto, Sudderth, Jessica, Sánchez-Martín, Marta, Belver, Laura, Tosello, Valeria, Xu, Luyao, Wendorff, Agnieszka A., Castillo, Mireia, Haydu, J. Erika, Márquez, Javier, Matés, José M., Kung, Andrew L., Rayport, Stephen, Cordon-Cardo, Carlos, DeBerardinis, Ralph J., Ferrando, Adolfo A.
Publicado 2015

The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia

por Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
Publicado 2018

Clonal evolution mechanisms in NT5C2 mutant relapsed acute lymphoblastic leukemia

por Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
Publicado 2018

Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias

por Wang, Kai, Sanchez-Martin, Marta, Wang, Xujun, Knapp, Kristina M., Koche, Richard, Vu, Ly, Nahas, Michelle K., He, Jie, Hadler, Michael, Stein, Eytan M, Tallman, Martin S., Donahue, Amy L, Frampton, Garrett M, Lipson, Doron, Roels, Steven, Stephens, Philip J., Sanford, Eric M, Brennan, Tim, Otto, Geoff A., Yelensky, Roman, Miller, Vincent A., Kharas, Michael G., Levine, Ross L., Ferrando, Adolfo, Armstrong, Scott A., Krivtsov, Andrei V.
Publicado 2016