New Thiophenyl-pyrazolyl-thiazole Hybrids as DHFR Inhibitors: Design, Synthesis, Antimicrobial Evaluation, Molecular Modeling, and Biodistribution Studies

por Dawood, Dina H., Sayed, Manal M., Tohamy, Sally T. K., Nossier, Eman S.
Publicado 2023

Design, Synthesis, Anticancer Evaluation, Enzymatic Assays, and a Molecular Modeling Study of Novel Pyrazole–Indole Hybrids

por Hassan, Ashraf S., Moustafa, Gaber O., Awad, Hanem M., Nossier, Eman S., Mady, Mohamed F.
Publicado 2021

New pyrazolopyridine and pyrazolothiazole-based compounds as anti-proliferative agents targeting c-Met kinase inhibition: design, synthesis, biological evaluation, and computationa...

por Alamshany, Zahra M., Algamdi, Eman M., Othman, Ismail M. M., Anwar, Manal M., Nossier, Eman S.
Publicado 2023

Anticancer evaluation and molecular modeling of multi-targeted kinase inhibitors based pyrido[2,3-d]pyrimidine scaffold

por Elzahabi, Heba S. A., Nossier, Eman S., Khalifa, Nagy M., Alasfoury, Rania A., El-Manawaty, May A.
Publicado 2018

Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents

por Nossier, Eman S., Fahmy, Hoda H., Khalifa, Nagy M., El-Eraky, Wafaa I., Baset, Marawan A.
Publicado 2017

Biological Validation of Novel Polysubstituted Pyrazole Candidates with in Vitro Anticancer Activities

por Fahmy, Hoda H., Khalifa, Nagy M., Ismail, Magda M. F., El-Sahrawy, Hend M., Nossier, Eman S.
Publicado 2016

Synthesis, Antimicrobial Activity and Molecular Docking of Novel Thiourea Derivatives Tagged with Thiadiazole, Imidazole and Triazine Moieties as Potential DNA Gyrase and Topoisome...

por Hashem, Heba E., Amr, Abd El-Galil E., Nossier, Eman S., Elsayed, Elsayed A., Azmy, Eman M.
Publicado 2020

New Benzimidazole-, 1,2,4-Triazole-, and 1,3,5-Triazine-Based Derivatives as Potential EGFR(WT) and EGFR(T790M) Inhibitors: Microwave-Assisted Synthesis, Anticancer Evaluation, and...

por Hashem, Heba E., Amr, Abd El-Galil E., Nossier, Eman S., Anwar, Manal M., Azmy, Eman M.
Publicado 2022

Antibacterial Evaluation, In Silico Characters and Molecular Docking of Schiff Bases Derived from 5-aminopyrazoles

por Hassan, Ashraf S., Askar, Ahmed A., Nossier, Eman S., Naglah, Ahmed M., Moustafa, Gaber O., Al-Omar, Mohamed A.
Publicado 2019

Synthesis, Docking Studies, and In Vitro Evaluation of Some Novel Thienopyridines and Fused Thienopyridine–Quinolines as Antibacterial Agents and DNA Gyrase Inhibitors

por Mohi El-Deen, Eman M., Abd El-Meguid, Eman A., Hasabelnaby, Sherifa, Karam, Eman A., Nossier, Eman S.
Publicado 2019

Synthesis and Biological Evaluation of New Pyridothienopyrimidine Derivatives as Antibacterial Agents and Escherichia coli Topoisomerase II Inhibitors

por Mohi El-Deen, Eman M., Abd El-Meguid, Eman A., Karam, Eman A., Nossier, Eman S., Ahmed, Marwa F.
Publicado 2020

Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2

por El-Sayed, Wael A., Alminderej, Fahad M., Mounier, Marwa M., Nossier, Eman S., Saleh, Sayed M., Kassem, Asmaa F.
Publicado 2022

New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking S...

por El-Sayed, Wael A., Alminderej, Fahad M., Mounier, Marwa M., Nossier, Eman S., Saleh, Sayed M., F. Kassem, Asmaa
Publicado 2022

Kinase Inhibitory Activities and Molecular Docking of a Novel Series of Anticancer Pyrazole Derivatives

por Nossier, Eman S., Abd El-Karim, Somaia S., Khalifa, Nagy M., El-Sayed, Ali S., Hassan, Emad S. I., El-Hallouty, Salwa M.
Publicado 2018

Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies

por Othman, Ismail M. M., Gad-Elkareem, Mohamed A. M., El-Naggar, Mohamed, Nossier, Eman S., Amr, Abd El-Galil E.
Publicado 2019

Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide–Glycyrrhetinic-Acid-Based Derivatives

por Moustafa, Gaber O., Shalaby, Ahmed, Naglah, Ahmed M., Mounier, Marwa M., El-Sayed, Heba, Anwar, Manal M., Nossier, Eman S.
Publicado 2021

Design, Synthesis, Anticancer Activity and Molecular Docking of New 1,2,3-Triazole-Based Glycosides Bearing 1,3,4-Thiadiazolyl, Indolyl and Arylacetamide Scaffolds

por Elganzory, Hussein H., Alminderej, Fahad M., El-Bayaa, Mohamed N., Awad, Hanem M., Nossier, Eman S., El-Sayed, Wael A.
Publicado 2022

In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N(1),N(3)-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide

por Kassem, Asmaa F., Moustafa, Gaber O., Nossier, Eman S., Khalaf, Hemat S., Mounier, Marwa M., Al-Yousef, Suliman A., Mahmoud, Sabry Y.
Publicado 2019

Chiral Pyridine-3,5-bis- (L-phenylalaninyl-L-leucinyl) Schiff Base Peptides as Potential Anticancer Agents: Design, Synthesis, and Molecular Docking Studies Targeting Lactate Dehyd...

por Amr, Abd El-Galil E., Mageid, Randa E. Abdel, El-Naggar, Mohamed, M. Naglah, Ahmed, S. Nossier, Eman, Elsayed, Elsayed A.
Publicado 2020

Design, Synthesis and Docking Studies of Novel Macrocyclic Pentapeptides as Anticancer Multi-Targeted Kinase Inhibitors

por Amr, Abd El-Galil E., Abo-Ghalia, Mohamed H., Moustafa, Gaber O., Al-Omar, Mohamed A., Nossier, Eman S., Elsayed, Elsayed A.
Publicado 2018