Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia

por Woll, Petter S., Yoshizato, Tetsuichi, Hellström‐Lindberg, Eva, Fioretos, Thoas, Ebert, Benjamin L., Jacobsen, Sten Eirik W.
Publicado 2022

Mapping the CLEC12A expression on myeloid progenitors in normal bone marrow; implications for understanding CLEC12A‐related cancer stem cell biology

por Bill, Marie, B. van Kooten Niekerk, Peter, S. Woll, Petter, Laine Herborg, Laura, Stidsholt Roug, Anne, Hokland, Peter, Nederby, Line
Publicado 2018

Aged healthy mice acquire clonal hematopoiesis mutations

por Chin, Desmond Wai Loon, Yoshizato, Tetsuichi, Virding Culleton, Stina, Grasso, Francesca, Barbachowska, Magdalena, Ogawa, Seishi, Jacobsen, Sten Eirik W., Woll, Petter S.
Publicado 2022

Identification of a KIR antisense lncRNA expressed by progenitor cells

por Wright, Paul W., Huehn, Andrew, Cichocki, Frank, Li, Hongchuan, Sharma, Neeraj, Dang, Hong, Lenvik, Todd R., Woll, Petter, Kaufman, Dan, Miller, Jeffrey S., Anderson, Stephen K.
Publicado 2013

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality

por Dimitriou, Marios, Woll, Petter S., Mortera-Blanco, Teresa, Karimi, Mohsen, Wedge, David C., Doolittle, Helen, Douagi, Iyadh, Papaemmanuil, Elli, Jacobsen, Sten Eirik W., Hellström-Lindberg, Eva
Publicado 2016

A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes

por Elvarsdóttir, Edda María, Mortera-Blanco, Teresa, Dimitriou, Marios, Bouderlique, Thibault, Jansson, Monika, Hofman, Isabel Juliana F., Conte, Simona, Karimi, Mohsen, Sander, Birgitta, Douagi, Iyadh, Woll, Petter S., Hellström-Lindberg, Eva
Publicado 2019

Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing

por Drissen, Roy, Buza-Vidas, Natalija, Woll, Petter, Thongjuea, Supat, Gambardella, Adriana, Giustacchini, Alice, Mancini, Elena, Zriwil, Alya, Lutteropp, Michael, Grover, Amit, Mead, Adam, Sitnicka, Ewa, Jacobsen, Sten Eirik W., Nerlov, Claus
Publicado 2016

Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations

por Scharenberg, Christian, Giai, Valentina, Pellagatti, Andrea, Saft, Leonie, Dimitriou, Marios, Jansson, Monika, Jädersten, Martin, Grandien, Alf, Douagi, Iyadh, Neuberg, Donna S., LeBlanc, Katarina, Boultwood, Jacqueline, Karimi, Mohsen, Jacobsen, Sten Eirik W., Woll, Petter S., Hellström-Lindberg, Eva
Publicado 2017

The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS

por Hofman, Isabel Juliana F., Mortera-Blanco, Teresa, Moura, Pedro Luis, Vestlund, Johanna, Larsson, Sigita Venckute, Elvarsdottir, Edda M., Walldin, Gunilla, Tobiasson, Magnus, Sander, Birgitta, Dimitriou, Marios, Jacobsen, Sten-Eirik W., Woll, Petter S., Jädersten, Martin, Hellström-Lindberg, Eva
Publicado 2022

P713: EXPLORING CLONAL COMPETITION THROUGH 12-YEAR FOLLOW-UP OF AN MDS-RS PATIENT WITH DUAL SF3B1 MUTATIONS

por Moura, Pedro, Hofman, Isabel, Nannya, Yasuhito, Aliouat, Affaf, Mortera-Blanco, Teresa, Yoshizato, Tetsuichi, Saiki, Ryunosuke, Nakagawa, Masahiro, Björklund, Ann-Charlotte, Walldin, Gunilla, Barbosa, Indira, Jansson, Monika, Grasso, Francesca, Creignou, Maria, Elvarsdottir, Edda, Woll, Petter, Eirik Jacobsen, Sten, Ogawa, Seishi, Hellström Lindberg, Eva
Publicado 2023

Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells

por Belander Strålin, Karin, Carrelha, Joana, Winroth, Axel, Ziegenhain, Christoph, Hagemann-Jensen, Michael, Kettyle, Laura M., Hillen, Amy, Högstrand, Kari, Markljung, Ellen, Grasso, Francesca, Seki, Masafumi, Mazzi, Stefania, Meng, Yiran, Wu, Bishan, Chari, Edwin, Lehander, Madeleine, Sandberg, Rickard, Woll, Petter S., Jacobsen, Sten Eirik W.
Publicado 2023

FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors

por Peña-Pérez, Lucía, Kharazi, Shabnam, Frengen, Nicolai, Krstic, Aleksandra, Bouderlique, Thibault, Hauenstein, Julia, He, Minghui, Somuncular, Ece, Li Wang, Xiaoze, Dahlberg, Carin, Gustafsson, Charlotte, Johansson, Ann-Sofie, Walfridsson, Julian, Kadri, Nadir, Woll, Petter, Kierczak, Marcin, Qian, Hong, Westerberg, Lisa, Luc, Sidinh, Månsson, Robert
Publicado 2022

FLT3-ITDs Instruct a Myeloid Differentiation and Transformation Bias in Lymphomyeloid Multipotent Progenitors

por Mead, Adam J., Kharazi, Shabnam, Atkinson, Deborah, Macaulay, Iain, Pecquet, Christian, Loughran, Stephen, Lutteropp, Michael, Woll, Petter, Chowdhury, Onima, Luc, Sidinh, Buza-Vidas, Natalija, Ferry, Helen, Clark, Sally-Ann, Goardon, Nicolas, Vyas, Paresh, Constantinescu, Stefan N., Sitnicka, Ewa, Nerlov, Claus, Jacobsen, Sten Eirik W.
Publicado 2013

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation

por Mead, Adam J., Neo, Wen Hao, Barkas, Nikolaos, Matsuoka, Sahoko, Giustacchini, Alice, Facchini, Raffaella, Thongjuea, Supat, Jamieson, Lauren, Booth, Christopher A.G., Fordham, Nicholas, Di Genua, Cristina, Atkinson, Deborah, Chowdhury, Onima, Repapi, Emmanouela, Gray, Nicki, Kharazi, Shabnam, Clark, Sally-Ann, Bouriez, Tiphaine, Woll, Petter, Suda, Toshio, Nerlov, Claus, Jacobsen, Sten Eirik W.
Publicado 2017

Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion

por Wojtowicz, Edyta E., Mistry, Jayna J., Uzun, Vladimir, Hellmich, Charlotte, Scoones, Anita, Chin, Desmond W., Kettyle, Laura M., Grasso, Francesca, Lord, Allegra M., Wright, David J., Etherington, Graham J., Woll, Petter S., Belderbos, Mirjam E., Bowles, Kristian M., Nerlov, Claus, Haerty, Wilfried, Bystrykh, Leonid V., Jacobsen, Sten Eirik W., Rushworth, Stuart A., Macaulay, Iain C.
Publicado 2023

Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts

por Todisco, Gabriele, Creignou, Maria, Bernard, Elsa, Björklund, Ann-Charlotte, Moura, Pedro Luis, Tesi, Bianca, Mortera-Blanco, Teresa, Sander, Birgitta, Jansson, Monika, Walldin, Gunilla, Barbosa, Indira, Reinsbach, Susanne E., Hofman, Isabel Juliana, Nilsson, Christer, Yoshizato, Tetsuichi, Dimitriou, Marios, Chang, David, Olafsdottir, Svannildur, Venckute Larsson, Sigita, Tobiasson, Magnus, Malcovati, Luca, Woll, Petter, Jacobsen, Sten Eirik W., Papaemmanuil, Elli, Hellström-Lindberg, Eva
Publicado 2023

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo

por Giannakopoulou, Eirini, Lehander, Madeleine, Virding Culleton, Stina, Yang, Weiwen, Li, Yingqian, Karpanen, Terhi, Yoshizato, Tetsuichi, Rustad, Even H., Nielsen, Morten Milek, Bollineni, Ravi Chand, Tran, Trung T., Delic-Sarac, Marina, Gjerdingen, Thea Johanne, Douvlataniotis, Karolos, Laos, Maarja, Ali, Muhammad, Hillen, Amy, Mazzi, Stefania, Chin, Desmond Wai Loon, Mehta, Adi, Holm, Jeppe Sejerø, Bentzen, Amalie Kai, Bill, Marie, Griffioen, Marieke, Gedde-Dahl, Tobias, Lehmann, Sören, Jacobsen, Sten Eirik W., Woll, Petter S., Olweus, Johanna
Publicado 2023

The Earliest Thymic T Cell Progenitors Sustain B Cell and Myeloid Lineage Potentials

por Luc, Sidinh, Luis, Tiago C., Boukarabila, Hanane, Macaulay, Iain C., Buza-Vidas, Natalija, Bouriez-Jones, Tiphaine, Lutteropp, Michael, Woll, Petter S., Loughran, Stephen J., Mead, Adam J., Hultquist, Anne, Brown, John, Mizukami, Takuo, Matsuoka, Sahoko, Ferry, Helen, Anderson, Kristina, Duarte, Sara, Atkinson, Deborah, Soneji, Shamit, Domanski, Aniela, Farley, Alison, Sanjuan-Pla, Alejandra, Carella, Cintia, Patient, Roger, de Bruijn, Marella, Enver, Tariq, Nerlov, Claus, Blackburn, Clare, Godin, Isabelle, Jacobsen, Sten Eirik W.
Publicado 2012

Genome-wide transcription factor–binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs

por Subramanian, Shruthi, Thoms, Julie A. I., Huang, Yizhou, Cornejo-Páramo, Paola, Koch, Forrest C., Jacquelin, Sebastien, Shen, Sylvie, Song, Emma, Joshi, Swapna, Brownlee, Chris, Woll, Petter S., Chacon-Fajardo, Diego, Beck, Dominik, Curtis, David J., Yehson, Kenneth, Antonenas, Vicki, O'Brien, Tracey, Trickett, Annette, Powell, Jason A., Lewis, Ian D., Pitson, Stuart M., Gandhi, Maher K., Lane, Steven W., Vafaee, Fatemeh, Wong, Emily S., Göttgens, Berthold, Alinejad-Rokny, Hamid, Wong, Jason W. H., Pimanda, John E.
Publicado 2023

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes

por Ali, Muhammad, Giannakopoulou, Eirini, Li, Yingqian, Lehander, Madeleine, Virding Culleton, Stina, Yang, Weiwen, Knetter, Cathrine, Odabasi, Mete Can, Bollineni, Ravi Chand, Yang, Xinbo, Foldvari, Zsofia, Böschen, Maxi-Lu, Taraldsrud, Eli, Strønen, Erlend, Toebes, Mireille, Hillen, Amy, Mazzi, Stefania, de Ru, Arnoud H., Janssen, George M. C., Kolstad, Arne, Tjønnfjord, Geir Erland, Lie, Benedicte A., Griffioen, Marieke, Lehmann, Sören, Osnes, Liv Toril, Buechner, Jochen, Garcia, K. Christopher, Schumacher, Ton N., van Veelen, Peter A., Leisegang, Matthias, Jacobsen, Sten Eirik W., Woll, Petter, Olweus, Johanna
Publicado 2021