Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection

por Wang, Jiao, Kano, Kuniyuki, Saigusa, Daisuke, Aoki, Junken
Publicado 2019

Modulations of bioactive lipids and their receptors in postmortem Alzheimer’s disease brains

por Kurano, Makoto, Saito, Yuko, Uranbileg, Baasanjav, Saigusa, Daisuke, Kano, Kuniyuki, Aoki, Junken, Yatomi, Yutaka
Publicado 2022

Nrf2 deficiency deteriorates diabetic kidney disease in Akita model mice

por Liu, Yexin, Uruno, Akira, Saito, Ritsumi, Matsukawa, Naomi, Hishinuma, Eiji, Saigusa, Daisuke, Liu, Hong, Yamamoto, Masayuki
Publicado 2022

Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging

por ABE, Takatsugu, NIIZUMA, Kuniyasu, KANOKE, Atsushi, SAIGUSA, Daisuke, SAITO, Ritsumi, URUNO, Akira, FUJIMURA, Miki, YAMAMOTO, Masayuki, TOMINAGA, Teiji
Publicado 2018

Heterologous expression of high-activity cytochrome P450 in mammalian cells

por Kumondai, Masaki, Hishinuma, Eiji, Gutiérrez Rico, Evelyn Marie, Ito, Akio, Nakanishi, Yuya, Saigusa, Daisuke, Hirasawa, Noriyasu, Hiratsuka, Masahiro
Publicado 2020

Urine autotaxin levels reflect the disease activity of sarcoidosis

por Murakami, Koji, Tamada, Tsutomu, Saigusa, Daisuke, Miyauchi, Eisaku, Nara, Masayuki, Ichinose, Masakazu, Kurano, Makoto, Yatomi, Yutaka, Sugiura, Hisatoshi
Publicado 2022

jMorp: Japanese Multi Omics Reference Panel

por Tadaka, Shu, Saigusa, Daisuke, Motoike, Ikuko N, Inoue, Jin, Aoki, Yuichi, Shirota, Matsuyuki, Koshiba, Seizo, Yamamoto, Masayuki, Kinoshita, Kengo
Publicado 2018

Distributions of CHN compounds in meteorites record organic syntheses in the early solar system

por Furukawa, Yoshihiro, Saigusa, Daisuke, Kano, Kuniyuki, Uruno, Akira, Saito, Ritsumi, Ito, Motoo, Matsumoto, Megumi, Aoki, Junken, Yamamoto, Masayuki, Nakamura, Tomoki
Publicado 2023

Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach

por Rashad, Sherif, Saigusa, Daisuke, Yamazaki, Takahiro, Matsumoto, Yotaro, Tomioka, Yoshihisa, Saito, Ritsumi, Uruno, Akira, Niizuma, Kuniyasu, Yamamoto, Masayuki, Tominaga, Teiji
Publicado 2020

Indole-3-acetic acid synthesized through the indole-3-pyruvate pathway promotes Candida tropicalis biofilm formation

por Miyagi, Masaru, Wilson, Rachel, Saigusa, Daisuke, Umeda, Keiko, Saijo, Reina, Hager, Christopher L., Li, Yuejin, McCormick, Thomas, Ghannoum, Mahmoud A.
Publicado 2020

Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function

por Nakamura, Atsushi, Ebina-Shibuya, Risa, Itoh-Nakadai, Ari, Muto, Akihiko, Shima, Hiroki, Saigusa, Daisuke, Aoki, Junken, Ebina, Masahito, Nukiwa, Toshihiro, Igarashi, Kazuhiko
Publicado 2013

Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlie...

por Uranbileg, Baasanjav, Ikeda, Hitoshi, Kurano, Makoto, Enooku, Kenichiro, Sato, Masaya, Saigusa, Daisuke, Aoki, Junken, Ishizawa, Takeaki, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Publicado 2016

Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human

por Sato, Masaya, Ikeda, Hitoshi, Uranbileg, Baasanjav, Kurano, Makoto, Saigusa, Daisuke, Aoki, Junken, Maki, Harufumi, Kudo, Hiroki, Hasegawa, Kiyoshi, Kokudo, Norihiro, Yatomi, Yutaka
Publicado 2016

Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS

por Kanemitsu, Yoshitomi, Mishima, Eikan, Maekawa, Masamitsu, Matsumoto, Yotaro, Saigusa, Daisuke, Yamaguchi, Hiroaki, Ogura, Jiro, Tsukamoto, Hiroki, Tomioka, Yoshihisa, Abe, Takaaki, Mano, Nariyasu
Publicado 2019

Lipidome-based rapid diagnosis with machine learning for detection of TGF-β signalling activated area in head and neck cancer

por Ishii, Hiroki, Saitoh, Masao, Sakamoto, Kaname, Sakamoto, Kei, Saigusa, Daisuke, Kasai, Hirotake, Ashizawa, Kei, Miyazawa, Keiji, Takeda, Sen, Masuyama, Keisuke, Yoshimura, Kentaro
Publicado 2020

Licochalcones extracted from Glycyrrhiza inflata inhibit platelet aggregation accompanied by inhibition of COX-1 activity

por Okuda-Tanino, Asa, Sugawara, Daiki, Tashiro, Takumi, Iwashita, Masaya, Obara, Yutaro, Moriya, Takahiro, Tsushima, Chisato, Saigusa, Daisuke, Tomioka, Yoshihisa, Ishii, Kuniaki, Nakahata, Norimichi
Publicado 2017

Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation

por Ishimaru, Kazuhiro, Yoshioka, Kazuaki, Kano, Kuniyuki, Kurano, Makoto, Saigusa, Daisuke, Aoki, Junken, Yatomi, Yutaka, Takuwa, Noriko, Okamoto, Yasuo, Proia, Richard L., Takuwa, Yoh
Publicado 2019

Impacts of NRF2 activation in non–small‐cell lung cancer cell lines on extracellular metabolites

por Saigusa, Daisuke, Motoike, Ikuko N., Saito, Sakae, Zorzi, Michael, Aoki, Yuichi, Kitamura, Hiroshi, Suzuki, Mikiko, Katsuoka, Fumiki, Ishii, Hirofumi, Kinoshita, Kengo, Motohashi, Hozumi, Yamamoto, Masayuki
Publicado 2020

Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model

por Uranbileg, Baasanjav, Ito, Nobuko, Kurano, Makoto, Saigusa, Daisuke, Saito, Ritsumi, Uruno, Akira, Kano, Kuniyuki, Ikeda, Hitoshi, Yamada, Yoshitsugu, Sumitani, Masahiko, Sekiguchi, Miho, Aoki, Junken, Yatomi, Yutaka
Publicado 2019

Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19

por Kurano, Makoto, Okamoto, Koh, Jubishi, Daisuke, Hashimoto, Hideki, Sakai, Eri, Saigusa, Daisuke, Kano, Kuniyuki, Aoki, Junken, Harada, Sohei, Okugawa, Shu, Doi, Kent, Moriya, Kyoji, Yatomi, Yutaka
Publicado 2022