My journey into the world of sphingolipids and sphingolipidoses

por SANDHOFF, Konrad
Publicado 2012

Secondary ganglioside GM2 accumulation in mucopolysaccharidoses

por Sandhoff, Konrad
Publicado 2021

Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease

por Breiden, Bernadette, Sandhoff, Konrad
Publicado 2020

Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism

por Breiden, Bernadette, Sandhoff, Konrad
Publicado 2021

Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2

por Oninla, Vincent O., Breiden, Bernadette, Babalola, Jonathan O., Sandhoff, Konrad
Publicado 2014

Overexpression of Acid Ceramidase Protects from Tumor Necrosis Factor–Induced Cell Death

por Strelow, Astrid, Bernardo, Katussevani, Adam-Klages, Sabine, Linke, Thomas, Sandhoff, Konrad, Krönke, Martin, Adam, Dieter
Publicado 2000

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion

por Abdul-Hammed, Misbaudeen, Breiden, Bernadette, Adebayo, Matthew A., Babalola, Jonathan O., Schwarzmann, Günter, Sandhoff, Konrad
Publicado 2010

The epidermal barrier function is dependent on the serine protease CAP1/Prss8

por Leyvraz, Céline, Charles, Roch-Philippe, Rubera, Isabelle, Guitard, Marjorie, Rotman, Samuel, Breiden, Bernadette, Sandhoff, Konrad, Hummler, Edith
Publicado 2005

Nrf2 links epidermal barrier function with antioxidant defense

por Schäfer, Matthias, Farwanah, Hany, Willrodt, Ann-Helen, Huebner, Aaron J, Sandhoff, Konrad, Roop, Dennis, Hohl, Daniel, Bloch, Wilhelm, Werner, Sabine
Publicado 2012

Characterization of Drosophila Saposin-related mutants as a model for lysosomal sphingolipid storage diseases

por Sellin, Julia, Schulze, Heike, Paradis, Marie, Gosejacob, Dominic, Papan, Cyrus, Shevchenko, Andrej, Psathaki, Olympia Ekaterina, Paululat, Achim, Thielisch, Melanie, Sandhoff, Konrad, Hoch, Michael
Publicado 2017

Unbalanced lipolysis results in lipotoxicity and mitochondrial damage in peroxisome-deficient Pex19 mutants

por Bülow, Margret H., Wingen, Christian, Senyilmaz, Deniz, Gosejacob, Dominic, Sociale, Mariangela, Bauer, Reinhard, Schulze, Heike, Sandhoff, Konrad, Teleman, Aurelio A., Hoch, Michael, Sellin, Julia
Publicado 2018

In Human and Mouse Spino-Cerebellar Tissue, Ataxin-2 Expansion Affects Ceramide-Sphingomyelin Metabolism

por Sen, Nesli-Ece, Arsovic, Aleksandar, Meierhofer, David, Brodesser, Susanne, Oberschmidt, Carola, Canet-Pons, Júlia, Kaya, Zeynep-Ece, Halbach, Melanie-Vanessa, Gispert, Suzana, Sandhoff, Konrad, Auburger, Georg
Publicado 2019

Role for LAMP-2 in endosomal cholesterol transport

por Schneede, Alexander, Schmidt, Christine K, Hölttä-Vuori, Maarit, Heeren, Jörg, Willenborg, Marion, Blanz, Judith, Domanskyy, Mykola, Breiden, Bernadette, Brodesser, Susanne, Landgrebe, Jobst, Sandhoff, Konrad, Ikonen, Elina, Saftig, Paul, Eskelinen, Eeva-Liisa
Publicado 2011

Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics

por Raju, Diana, Schonauer, Sophie, Hamzeh, Hussein, Flynn, Kevin C., Bradke, Frank, vom Dorp, Katharina, Dörmann, Peter, Yildiz, Yildiz, Trötschel, Christian, Poetsch, Ansgar, Breiden, Bernadette, Sandhoff, Konrad, Körschen, Heinz G., Wachten, Dagmar
Publicado 2015

PAR2 absence completely rescues inflammation and ichthyosis caused by altered CAP1/Prss8 expression in mouse skin

por Frateschi, Simona, Camerer, Eric, Crisante, Giovanna, Rieser, Sarah, Membrez, Mathieu, Charles, Roch-Philippe, Beermann, Friedrich, Stehle, Jean-Christophe, Breiden, Bernadette, Sandhoff, Konrad, Rotman, Samuel, Haftek, Marek, Wilson, Anne, Ryser, Stephan, Steinhoff, Martin, Coughlin, Shaun R., Hummler, Edith
Publicado 2011

Functional and genetic characterization of the non-lysosomal glucosylceramidase 2 as a modifier for Gaucher disease

por Yildiz, Yildiz, Hoffmann, Per, vom Dahl, Stefan, Breiden, Bernadette, Sandhoff, Roger, Niederau, Claus, Horwitz, Mia, Karlsson, Stefan, Filocamo, Mirella, Elstein, Deborah, Beck, Michael, Sandhoff, Konrad, Mengel, Eugen, Gonzalez, Maria C, Nöthen, Markus M, Sidransky, Ellen, Zimran, Ari, Mattheisen, Manuel
Publicado 2013

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice

por Schäfer, Matthias, Willrodt, Ann-Helen, Kurinna, Svitlana, Link, Andrea S, Farwanah, Hany, Geusau, Alexandra, Gruber, Florian, Sorg, Olivier, Huebner, Aaron J, Roop, Dennis R, Sandhoff, Konrad, Saurat, Jean-Hilaire, Tschachler, Erwin, Schneider, Marlon R, Langbein, Lutz, Bloch, Wilhelm, Beer, Hans-Dietmar, Werner, Sabine
Publicado 2014