Psoriasis Pathogenesis and Treatment

por Rendon, Adriana, Schäkel, Knut
Publicado 2019

Current Concepts on 6-sulfo LacNAc Expressing Monocytes (slanMo)

por Ahmad, Fareed, Döbel, Thomas, Schmitz, Marc, Schäkel, Knut
Publicado 2019

The CD16(+) (FcγRIII(+)) Subset of Human Monocytes Preferentially Becomes Migratory Dendritic Cells in a Model Tissue Setting

por Randolph, Gwendalyn J., Sanchez-Schmitz, Guzman, Liebman, Ronald M., Schäkel, Knut
Publicado 2002

Quality of life, treatment satisfaction and efficacy of non-biological systemic therapies in patients with plaque psoriasis: study protocol for a prospective observational study

por Fink, Christine, Schank, Timo E, Trenkler, Nina, Uhlmann, Lorenz, Schäkel, Knut
Publicado 2017

Evaluation of Psoriasis Area and Severity Index as a Proxy for Biomarkers of Systemic Disease under Treatment with Tumour Necrosis Factor-alpha and Interleukin 12/23 Antagonists in...

por HOFFMANN, Jochen H. O., KNOOP, Chriatian, SCHÄKEL, Knut, ENK, Alexander H., HADASCHIK, Eva N.
Publicado 2021

Phenotype, Function, and Mobilization of 6-Sulfo LacNAc-Expressing Monocytes in Atopic Dermatitis

por Baran, Wojciech, Oehrl, Stephanie, Ahmad, Fareed, Döbel, Thomas, Alt, Christina, Buske-Kirschbaum, Angelika, Schmitz, Marc, Schäkel, Knut
Publicado 2018

Expression of FMRpolyG in Peripheral Blood Mononuclear Cells of Women with Fragile X Mental Retardation 1 Gene Premutation

por Nguyen, Xuan Phuoc, Vilkaite, Adriana, Messmer, Birgitta, Dietrich, Jens E., Hinderhofer, Katrin, Schäkel, Knut, Strowitzki, Thomas, Rehnitz, Julia
Publicado 2022

Immune complex-induced haptokinesis in human non-classical monocytes

por Preuß, Sophie L., Oehrl, Stephanie, Zhang, Hao, Döbel, Thomas, Engel, Ulrike, Young, Jennifer L., Spatz, Joachim P., Schäkel, Knut
Publicado 2023

Deciphering the Stromal and Hematopoietic Cell Network of the Adventitia from Non-Aneurysmal and Aneurysmal Human Aorta

por Dutertre, Charles-Antoine, Clement, Marc, Morvan, Marion, Schäkel, Knut, Castier, Yves, Alsac, Jean-Marc, Michel, Jean-Baptiste, Nicoletti, Antonino
Publicado 2014

Keratinocyte-induced costimulation of human T cells through CD6 - but not CD2 - activates mTOR and prevents oxidative stress

por Orlik, Christian, Berschneider, Karina M., Jahraus, Beate, Niesler, Beate, Balta, Emre, Schäkel, Knut, Schröder-Braunstein, Jutta, Souto-Carneiro, Maria Margarida, Samstag, Yvonne
Publicado 2022

Corrigendum: Efficacy of ixekizumab in patients with moderate-to-severe plaque psoriasis and prediabetes or type 2 diabetes

por Egeberg, Alexander, Merola, Joseph F., Schäkel, Knut, Puig, Luis, Mahar, Patrick D., Wang, Isabella Yali, Pavo, Imre, Schuster, Christopher, Griffiths, Christopher E. M.
Publicado 2023

Keratinocytes costimulate naive human T cells via CD2: a potential target to prevent the development of proinflammatory Th1 cells in the skin

por Orlik, Christian, Deibel, Daniel, Küblbeck, Johanna, Balta, Emre, Ganskih, Sabina, Habicht, Jüri, Niesler, Beate, Schröder-Braunstein, Jutta, Schäkel, Knut, Wabnitz, Guido, Samstag, Yvonne
Publicado 2019

Human innate immune cell crosstalk induces melanoma cell senescence

por Funck, Felix, Pahl, Jens, Kyjacova, Lenka, Freund, Lukas, Oehrl, Stephanie, Gräbe, Galina, Pezer, Silvia, Hassel, Jessica C., Sleeman, Jonathan, Cerwenka, Adelheid, Schäkel, Knut
Publicado 2020

Behandlung der Psoriasis mit Secukinumab: Praxisrelevante Hinweise

por Körber, Andreas, Augustin, Matthias, Behrens, Frank, Gerdes, Sascha, von Kiedrowski, Ralph, Schäkel, Knut, Sticherling, Michael, Wilsmann-Theis, Dagmar, Wohlrab, Johannes, Simon, Jan-Christoph
Publicado 2021

Efficacy of ixekizumab in patients with moderate-to-severe plaque psoriasis and prediabetes or type 2 diabetes

por Egeberg, Alexander, Merola, Joseph F., Schäkel, Knut, Puig, Luis, Mahar, Patrick D., Wang, Isabella Yali, Pavo, Imre, Schuster, Christopher, Griffiths, Christopher E. M.
Publicado 2023

Accumulation and therapeutic modulation of 6-sulfo LacNAc(+) dendritic cells in multiple sclerosis

por Thomas, Katja, Dietze, Kristin, Wehner, Rebekka, Metz, Imke, Tumani, Hayrettin, Schultheiß, Thorsten, Günther, Claudia, Schäkel, Knut, Reichmann, Heinz, Brück, Wolfgang, Schmitz, Marc, Ziemssen, Tjalf
Publicado 2014

Keratinocyte-derived IκBζ drives psoriasis and associated systemic inflammation

por Lorscheid, Sebastian, Müller, Anne, Löffler, Jessica, Resch, Claudia, Bucher, Philip, Kurschus, Florian C., Waisman, Ari, Schäkel, Knut, Hailfinger, Stephan, Schulze-Osthoff, Klaus, Kramer, Daniela
Publicado 2019

Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pi...

por Mrowietz, Ulrich, Burden, A. David, Pinter, Andreas, Reich, Kristian, Schäkel, Knut, Baum, Patrick, Datsenko, Yakov, Deng, Hongjie, Padula, Steven J., Thoma, Christian, Bissonnette, Robert
Publicado 2021

IL-23 blockade with guselkumab potentially modifies psoriasis pathogenesis: rationale and study protocol of a phase 3b, randomised, double-blind, multicentre study in participants...

por Eyerich, Kilian, Weisenseel, Peter, Pinter, Andreas, Schäkel, Knut, Asadullah, Khusru, Wegner, Sven, Muñoz-Elias, Ernesto J, Bartz, Holger, Taut, Friedmann J H, Reich, Kristian
Publicado 2021

Detection of In Vivo Inflammasome Activation for Predicting Sepsis Mortality

por Cui, Jing, Oehrl, Stephanie, Ahmad, Fareed, Brenner, Thorsten, Uhle, Florian, Nusshag, Christian, Rupp, Christoph, Funck, Felix, Meisel, Stefan, Weigand, Markus A., Morath, Christian, Schäkel, Knut
Publicado 2021