Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities

por Basil, Paul, Robertson, Matthew J., Bingman, William E., Dash, Amit K., Krause, William C., Shafi, Ayesha A., Piyarathna, Badrajee, Coarfa, Cristian, Weigel, Nancy L.
Publicado 2022

Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression

por HE, SUQIN, ZHANG, CHAOHUA, SHAFI, AYESHA A., SEQUEIRA, MANUEL, ACQUAVIVA, JAIME, FRIEDLAND, JULIE C., SANG, JIM, SMITH, DONALD L., WEIGEL, NANCY L., WADA, YUMIKO, PROIA, DAVID A.
Publicado 2012

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

por Shafi, Ayesha A., Putluri, Vasanta, Arnold, James M., Tsouko, Efrosini, Maity, Suman, Roberts, Justin M., Coarfa, Cristian, Frigo, Daniel E., Putluri, Nagireddy, Sreekumar, Arun, Weigel, Nancy L.
Publicado 2015

Mutant p53 elicits context-dependent pro-tumorigenic phenotypes

por McCann, Jennifer J., Vasilevskaya, Irina A., McNair, Christopher, Gallagher, Peter, Neupane, Neermala Poudel, de Leeuw, Renée, Shafi, Ayesha A., Dylgjeri, Emanuela, Mandigo, Amy C., Schiewer, Matthew J., Knudsen, Karen E.
Publicado 2021

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer

por Gordon, Nicolas, Gallagher, Peter T., Neupane, Neermala Poudel, Mandigo, Amy C., McCann, Jennifer K., Dylgjeri, Emanuela, Vasilevskaya, Irina, McNair, Christopher, Paller, Channing J., Kelly, Wm. Kevin, Knudsen, Karen E., Shafi, Ayesha A., Schiewer, Matthew J.
Publicado 2023

Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer

por Mandigo, Amy C., Shafi, Ayesha A., McCann, Jennifer J., Yuan, Wei, Laufer, Talya S., Bogdan, Denisa, Gallagher, Lewis, Dylgjeri, Emanuela, Semenova, Galina, Vasilevskaya, Irina A., Schiewer, Matthew J., McNair, Chris M., de Bono, Johann S., Knudsen, Karen E.
Publicado 2022

The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair

por Shafi, Ayesha A., McNair, Chris M., McCann, Jennifer J., Alshalalfa, Mohammed, Shostak, Anton, Severson, Tesa M., Zhu, Yanyun, Bergman, Andre, Gordon, Nicolas, Mandigo, Amy C., Chand, Saswati N., Gallagher, Peter, Dylgjeri, Emanuela, Laufer, Talya S., Vasilevskaya, Irina A., Schiewer, Matthew J., Brunner, Michael, Feng, Felix Y., Zwart, Wilbert, Knudsen, Karen E.
Publicado 2021

A Novel Role for DNA-PK in Metabolism by Regulating Glycolysis in Castration-Resistant Prostate Cancer

por Dylgjeri, Emanuela, Kothari, Vishal, Shafi, Ayesha A., Semenova, Galina, Gallagher, Peter T., Guan, Yi F., Pang, Angel, Goodwin, Jonathan F., Irani, Swati, McCann, Jennifer J., Mandigo, Amy C., Chand, Saswati, McNair, Christopher M., Vasilevskaya, Irina, Schiewer, Matthew J., Lallas, Costas D., McCue, Peter A., Gomella, Leonard G., Seifert, Erin L., Carroll, Jason S., Butler, Lisa M., Holst, Jeff, Kelly, William K., Knudsen, Karen E.
Publicado 2022

PARP‐1 regulates DNA repair factor availability

por Schiewer, Matthew J, Mandigo, Amy C, Gordon, Nicolas, Huang, Fangjin, Gaur, Sanchaika, de Leeuw, Renée, Zhao, Shuang G, Evans, Joseph, Han, Sumin, Parsons, Theodore, Birbe, Ruth, McCue, Peter, McNair, Christopher, Chand, Saswati N, Cendon‐Florez, Ylenia, Gallagher, Peter, McCann, Jennifer J, Poudel Neupane, Neermala, Shafi, Ayesha A, Dylgjeri, Emanuela, Brand, Lucas J, Visakorpi, Tapio, Raj, Ganesh V, Lallas, Costas D, Trabulsi, Edouard J, Gomella, Leonard G, Dicker, Adam P, Kelly, Wm. Kevin, Leiby, Benjamin E, Knudsen, Beatrice, Feng, Felix Y, Knudsen, Karen E
Publicado 2018