Pancreatic cancers rely on a novel glutamine metabolism pathway to maintain redox balance

por Lyssiotis, Costas A., Son, Jaekyoung, Cantley, Lewis C., Kimmelman, Alec C.
Publicado 2013

Pancreatic cancers depend on a non-canonical glutamine metabolism pathway

por Lyssiotis, Costas, Son, Jaekyoung, Mancias, Joesph, Ying, Haoqiang, Kimmelman, Alec, Cantley, Lewis
Publicado 2014

Vitamin C Suppresses Pancreatic Carcinogenesis through the Inhibition of Both Glucose Metabolism and Wnt Signaling

por Kim, Ji Hye, Hwang, Sein, Lee, Ji-Hye, Im, Se Seul, Son, Jaekyoung
Publicado 2022

Branched-chain amino acids sustain pancreatic cancer growth by regulating lipid metabolism

por Lee, Ji Hyeon, Cho, Young-ra, Kim, Ji Hye, Kim, Jongwook, Nam, Hae Yun, Kim, Seong Who, Son, Jaekyoung
Publicado 2019

Role of Drosophila EDEMs in the degradation of the alpha-1-antitrypsin Z variant

por JANG, BO-YUN, RYOO, HYUNG DON, SON, JAEKYOUNG, CHOI, KYUNG-CHUL, SHIN, DONG-MYOUNG, KANG, SANG-WOOK, KANG, MIN-JI
Publicado 2015

Autophagy is required for PDAC glutamine metabolism

por Seo, Ju-Won, Choi, Jungwon, Lee, So-Yeon, Sung, Suhyun, Yoo, Hyun Ju, Kang, Min-Ji, Cheong, Heesun, Son, Jaekyoung
Publicado 2016

Dual targeting of glutaminase 1 and thymidylate synthase elicits death synergistically in NSCLC

por Lee, Jae-Seon, Kang, Joon H, Lee, Seon-Hyeong, Hong, Dongwan, Son, Jaekyoung, Hong, Kyeong M, Song, Jaewhan, Kim, Soo-Youl
Publicado 2016

TFEB Supports Pancreatic Cancer Growth through the Transcriptional Regulation of Glutaminase

por Kim, Ji Hye, Lee, Jinyoung, Cho, Young-Ra, Lee, So-Yeon, Sung, Gi-Jun, Shin, Dong-Myung, Choi, Kyung-Chul, Son, Jaekyoung
Publicado 2021

Human Plasmablast Migration Toward CXCL12 Requires Glucose Oxidation by Enhanced Pyruvate Dehydrogenase Activity via AKT

por Pak, Hyo-Kyung, Nam, Bora, Lee, Yoon Kyoung, Kim, Yong-Woo, Roh, Jin, Son, Jaekyoung, Chung, Yoo-Sam, Choe, Jongseon, Park, Chan-Sik
Publicado 2018

AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis

por Choi, Yun Jung, Kim, Ji Hye, Rho, Jin Kyung, Kim, Joong Sun, Choi, Chang-Min, Kim, Woo Sung, Son, Jaekyoung, Lee, Jae Cheol
Publicado 2019

Potent Anticancer Effect of the Natural Steroidal Saponin Gracillin Is Produced by Inhibiting Glycolysis and Oxidative Phosphorylation-Mediated Bioenergetics

por Min, Hye-Young, Pei, Honglan, Hyun, Seung Yeob, Boo, Hye-Jin, Jang, Hyun-Ji, Cho, Jaebeom, Kim, Ji Hye, Son, Jaekyoung, Lee, Ho-Young
Publicado 2020

BIX01294 inhibits EGFR signaling in EGFR-mutant lung adenocarcinoma cells through a BCKDHA-mediated reduction in the EGFR level

por Kim, Ji Hye, Kim, Jongwook, Im, Se Seul, Lee, Ji Hyeon, Hwang, Sein, Chang, Eun-Ju, Shin, Dong-Myung, Rho, Jin Kyung, Son, Jaekyoung
Publicado 2021

Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion

por Kang, Joon Hee, Lee, Seon-Hyeong, Lee, Jae-Seon, Nam, Boas, Seong, Tae Wha, Son, Jaekyoung, Jang, Hyonchol, Hong, Kyeong Man, Lee, Cheolju, Kim, Soo-Youl
Publicado 2016

Valproic acid enforces the priming effect of sphingosine-1 phosphate on human mesenchymal stem cells

por Lim, Jisun, Lee, Seungun, Ju, Hyein, Kim, Yonghwan, Heo, Jinbeom, Lee, Hye-Yeon, Choi, Kyung-Chul, Son, Jaekyoung, Oh, Yeon-Mok, Kim, In-Gyu, Shin, Dong-Myung
Publicado 2017

The natural compound gracillin exerts potent antitumor activity by targeting mitochondrial complex II

por Min, Hye-Young, Jang, Hyun-Ji, Park, Kwan Hee, Hyun, Seung Yeob, Park, So Jung, Kim, Ji Hye, Son, Jaekyoung, Kang, Sam Sik, Lee, Ho-Young
Publicado 2019

Delphinidin sensitizes prostate cancer cells to TRAIL-induced apoptosis, by inducing DR5 and causing caspase-mediated HDAC3 cleavage

por Ko, Hyeonseok, Jeong, Mi-Hyeon, Jeon, Hyelin, Sung, Gi-Jun, So, Youngsin, Kim, InKi, Son, JaeKyoung, Lee, Sang-wook, Yoon, Ho-Geun, Choi, Kyung-Chul
Publicado 2015

PPARγ sumoylation-mediated lipid accumulation in lung cancer

por Phan, Ai N.H., Vo, Vu T.A., Hua, Tuyen N.M., Kim, Min-Kyu, Jo, Se-Young, Choi, Jong-Whan, Kim, Hyun-Won, Son, Jaekyoung, Suh, Young-Ah, Jeong, Yangsik
Publicado 2017

Matrine suppresses KRAS‐driven pancreatic cancer growth by inhibiting autophagy‐mediated energy metabolism

por Cho, Young‐ra, Lee, Ji Hyeon, Kim, Ji Hye, Lee, So‐Yeon, Yoo, Suna, Jung, Min‐kyo, Kim, Su Jung, Yoo, Hyun Ju, Pack, Chang‐Gi, Rho, Jin Kyung, Son, Jaekyoung
Publicado 2018

Correction: PPARγ sumoylation-mediated lipid accumulation in lung cancer

por Phan, Ai N.H., Vo, Vu T.A., Hua, Tuyen N.M., Kim, Min-Kyu, Jo, Se-Young, Choi, Jong-Whan, Kim, Hyun-Won, Son, Jaekyoung, Suh, Young-Ah, Jeong, Yangsik
Publicado 2019

The CDK1/TFCP2L1/ID2 cascade offers a novel combination therapy strategy in a preclinical model of bladder cancer

por Heo, Jinbeom, Lee, Jinyoung, Nam, Yun Ji, Kim, YongHwan, Yun, HongDuck, Lee, Seungun, Ju, Hyein, Ryu, Chae-Min, Jeong, Seon Min, Lee, Jinwon, Lim, Jisun, Cho, Yong Mee, Jeong, Eui Man, Hong, Bumsik, Son, Jaekyoung, Shin, Dong-Myung
Publicado 2022