CD44v6-Targeted Imaging of Head and Neck Squamous Cell Carcinoma: Antibody-Based Approaches

por Spiegelberg, Diana, Nilvebrant, Johan
Publicado 2017

The HSP90 inhibitor onalespib potentiates (177)Lu-DOTATATE therapy in neuroendocrine tumor cells

por Lundsten, Sara, Spiegelberg, Diana, Stenerlöw, Bo, Nestor, Marika
Publicado 2019

K(D) determination from time-resolved experiments on live cells with LigandTracer and reconciliation with end-point flow cytometry measurements

por Spiegelberg, Diana, Stenberg, Jonas, Richalet, Pascale, Vanhove, Marc
Publicado 2021

The radiosensitizer Onalespib increases complete remission in (177)Lu-DOTATATE-treated mice bearing neuroendocrine tumor xenografts

por Lundsten, Sara, Spiegelberg, Diana, Raval, Nakul R., Nestor, Marika
Publicado 2020

Higher Risk of Recurrence in Patients Treated for Head and Neck Cancer with Low BMI and Elevated Levels of C-Reactive Protein

por Spiegelberg, Diana, Malmberg, Christer, Tiblom Ehrsson, Ylva, Laurell, Göran
Publicado 2022

Ra-223 induces clustered DNA damage and inhibits cell survival in several prostate cancer cell lines

por Abramenkovs, Andris, Hariri, Mehran, Spiegelberg, Diana, Nilsson, Sten, Stenerlöw, Bo
Publicado 2022

In vivo characterization of the novel CD44v6-targeting Fab fragment AbD15179 for molecular imaging of squamous cell carcinoma: a dual-isotope study

por Haylock, Anna-Karin, Spiegelberg, Diana, Nilvebrant, Johan, Sandström, Karl, Nestor, Marika
Publicado 2014

Evaluation of Cancer Stem Cell Markers CD133, CD44, CD24: Association with AKT Isoforms and Radiation Resistance in Colon Cancer Cells

por Sahlberg, Sara Häggblad, Spiegelberg, Diana, Glimelius, Bengt, Stenerlöw, Bo, Nestor, Marika
Publicado 2014

Preclinical evaluation of a novel engineered recombinant human anti-CD44v6 antibody for potential use in radio-immunotherapy

por Mortensen, Anja C., Spiegelberg, Diana, Haylock, Anna-Karin, Lundqvist, Hans, Nestor, Marika
Publicado 2018

Overcoming Limitations of Cisplatin Therapy by Additional Treatment With the HSP90 Inhibitor Onalespib

por Mortensen, Anja Charlotte Lundgren, Mohajershojai, Tabassom, Hariri, Mehran, Pettersson, Marika, Spiegelberg, Diana
Publicado 2020

Combination therapy of tyrosine kinase inhibitor sorafenib with the HSP90 inhibitor onalespib as a novel treatment regimen for thyroid cancer

por Mortensen, Anja Charlotte Lundgren, Berglund, Hanna, Hariri, Mehran, Papalanis, Eleftherios, Malmberg, Christer, Spiegelberg, Diana
Publicado 2023

Molecular imaging of EGFR and CD44v6 for prediction and response monitoring of HSP90 inhibition in an in vivo squamous cell carcinoma model

por Spiegelberg, Diana, Mortensen, Anja C., Selvaraju, Ram K., Eriksson, Olof, Stenerlöw, Bo, Nestor, Marika
Publicado 2015

The Stapled Peptide PM2 Stabilizes p53 Levels and Radiosensitizes Wild-Type p53 Cancer Cells

por Mortensen, Anja Charlotte Lundgren, Spiegelberg, Diana, Brown, Christopher John, Lane, David Philip, Nestor, Marika
Publicado 2019

The HSP90 inhibitor Onalespib exerts synergistic anti-cancer effects when combined with radiotherapy: an in vitro and in vivo approach

por Spiegelberg, Diana, Abramenkovs, Andris, Mortensen, Anja Charlotte Lundgren, Lundsten, Sara, Nestor, Marika, Stenerlöw, Bo
Publicado 2020

The novel HSP90 inhibitor AT13387 potentiates radiation effects in squamous cell carcinoma and adenocarcinoma cells

por Spiegelberg, Diana, Dascalu, Adrian, Mortensen, Anja C., Abramenkovs, Andris, Kuku, Gamze, Nestor, Marika, Stenerlöw, Bo
Publicado 2015

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

por HAYLOCK, ANNA-KARIN, SPIEGELBERG, DIANA, MORTENSEN, ANJA C., SELVARAJU, RAM K., NILVEBRANT, JOHAN, ERIKSSON, OLOF, TOLMACHEV, VLADIMIR, NESTOR, MARIKA V.
Publicado 2015

The Novel Anti-cMet Antibody seeMet 12 Potentiates Sorafenib Therapy and Radiotherapy in a Colorectal Cancer Model

por Spiegelberg, Diana, Mortensen, Anja Charlotte Lundgren, Palupi, Kartika Dyah, Micke, Patrick, Wong, Julin, Vojtesek, Borivoj, Lane, David Philip, Nestor, Marika
Publicado 2020

Conformation specific antagonistic high affinity antibodies to the RON receptor kinase for imaging and therapy

por Yu Koh, Xin, Koh, Xiao Hui, Spiegelberg, Diana, Jha, Preeti, Nestor, Marika, Hwang, Le-ann, Tan, Ban Xiong, Lane, David Philip
Publicado 2022

The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth In Vivo and Potentiates Radiotherapy

por Ingelshed, Katrine, Spiegelberg, Diana, Kannan, Pavitra, Påvénius, Linnéa, Hacheney, Jessica, Jiang, Long, Eisinger, Silke, Lianoudaki, Danai, Lama, Dilraj, Castillo, Francisca, Bosdotter, Cecilia, Kretzschmar, Warren W., Al-Radi, Omayma, Fritz, Nicolas, Villablanca, Eduardo J., Karlsson, Mikael C. I., Wermeling, Fredrik, Nestor, Marika, Lane, David P., Sedimbi, Saikiran K.
Publicado 2022