Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms

por Hirose, Tomoyasu, Sunazuka, Toshiaki, Ōmura, Satoshi
Publicado 2010

Development of a nitrogen-bound hydrophobic auxiliary: application to solid/hydrophobic-tag relay synthesis of calpinactam

por Nakahara, Hiroki, Sennari, Goh, Noguchi, Yoshihiko, Hirose, Tomoyasu, Sunazuka, Toshiaki
Publicado 2023

Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid

por Noguchi, Yoshihiko, Hirose, Tomoyasu, Ishiyama, Aki, Iwatsuki, Masato, Otoguro, Kazuhiko, Sunazuka, Toshiaki, Ōmura, Satoshi
Publicado 2016

Afidopyropen, a novel insecticide originating from microbial secondary extracts

por Horikoshi, Ryo, Goto, Kimihiko, Mitomi, Masaaki, Oyama, Kazuhiko, Hirose, Tomoyasu, Sunazuka, Toshiaki, Ōmura, Satoshi
Publicado 2022

Synthesis of pyripyropene derivatives and their pest-control efficacy

por Goto, Kimihiko, Horikoshi, Ryo, Nakamura, Satoshi, Mitomi, Masaaki, Oyama, Kazuhiko, Hirose, Tomoyasu, Sunazuka, Toshiaki, Ōmura, Satoshi
Publicado 2019

Antimalarial troponoids, puberulic acid and viticolins; divergent synthesis and structure-activity relationship studies

por Sennari, Goh, Saito, Ryo, Hirose, Tomoyasu, Iwatsuki, Masato, Ishiyama, Aki, Hokari, Rei, Otoguro, Kazuhiko, Ōmura, Satoshi, Sunazuka, Toshiaki
Publicado 2017

Thioporidiols A and B: Two New Sulfur Compounds Discovered by Molybdenum-Catalyzed Oxidation Screening from Trichoderma polypori FKI-7382

por Matsuo, Hirotaka, Noguchi, Yoshihiko, Miyano, Rei, Higo, Mayuka, Nonaka, Kenichi, Sunazuka, Toshiaki, Takahashi, Yōko, Ōmura, Satoshi, Nakashima, Takuji
Publicado 2020

The non-antibiotic macrolide EM900 inhibits rhinovirus infection and cytokine production in human airway epithelial cells

por Lusamba Kalonji, Nadine, Nomura, Kazuhiro, Kawase, Tetsuaki, Ota, Chiharu, Kubo, Hiroshi, Sato, Takeya, Yanagisawa, Teruyuki, Sunazuka, Toshiaki, Ōmura, Satoshi, Yamaya, Mutsuo
Publicado 2015

The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model

por Sadamatsu, Hironori, Takahashi, Koichiro, Tashiro, Hiroki, Kato, Go, Noguchi, Yoshihiko, Kurata, Keigo, Ōmura, Satoshi, Kimura, Shinya, Sunazuka, Toshiaki, Sueoka-Aragane, Naoko
Publicado 2019

Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells

por Muneshige, Kyoko, Inahashi, Yuki, Itakura, Makoto, Iwatsuki, Masato, Hirose, Tomoyasu, Inoue, Gen, Takaso, Masashi, Sunazuka, Toshiaki, Ohashi, Yoshihisa, Ohta, Etsuro, Uchida, Kentaro
Publicado 2022

Variational autoencoder-based chemical latent space for large molecular structures with 3D complexity

por Ochiai, Toshiki, Inukai, Tensei, Akiyama, Manato, Furui, Kairi, Ohue, Masahito, Matsumori, Nobuaki, Inuki, Shinsuke, Uesugi, Motonari, Sunazuka, Toshiaki, Kikuchi, Kazuya, Kakeya, Hideaki, Sakakibara, Yasubumi
Publicado 2023

EM703 improves bleomycin-induced pulmonary fibrosis in mice by the inhibition of TGF-β signaling in lung fibroblasts

por Li, Ying Ji, Azuma, Arata, Usuki, Jiro, Abe, Shinji, Matsuda, Kuniko, Sunazuka, Toshiaki, Shimizu, Takako, Hirata, Yukiyo, Inagaki, Hirofumi, Kawada, Tomoyuki, Takahashi, Satoru, Kudoh, Shoji, Omura, Satoshi
Publicado 2006

Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines

por MUKAI, SHUNTARO, MORIYA, SHOTA, HIRAMOTO, MASAKI, KAZAMA, HIROMI, KOKUBA, HIROKO, CHE, XIAO-FANG, YOKOYAMA, TOMOHISA, SAKAMOTO, SATOSHI, SUGAWARA, AKIHIRO, SUNAZUKA, TOSHIAKI, ŌMURA, SATOSHI, HANDA, HIROSHI, ITOI, TAKAO, MIYAZAWA, KEISUKE
Publicado 2015

Fungal Secondary Metabolite Exophillic Acid Selectively Inhibits the Entry of Hepatitis B and D Viruses

por Kobayashi, Chisa, Watanabe, Yoshihiro, Oshima, Mizuki, Hirose, Tomoyasu, Yamasaki, Masako, Iwamoto, Masashi, Iwatsuki, Masato, Asami, Yukihiro, Kuramochi, Kouji, Wakae, Kousho, Aizaki, Hideki, Muramatsu, Masamichi, Sureau, Camille, Sunazuka, Toshiaki, Watashi, Koichi
Publicado 2022

Ivermectin represses Wnt/β-catenin signaling by binding to TELO2, a regulator of phosphatidylinositol 3-kinase-related kinases

por Yonezawa, Honami, Ikeda, Akari, Takahashi, Ryo, Endo, Haruka, Sugawara, Yasuyo, Goto, Mikako, Kanno, Mirute, Ogawa, Sosuke, Nakamura, Karin, Ujiie, Haruki, Iwatsuki, Masato, Hirose, Tomoyasu, Sunazuka, Toshiaki, Uehara, Yoshimasa, Nishiya, Naoyuki
Publicado 2022

Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2

por Nakanishi, Anna, Okumura, Hiroki, Hashita, Tadahiro, Yamashita, Aya, Nishimura, Yuka, Watanabe, Chihiro, Kamimura, Sakina, Hayashi, Sanae, Murakami, Shuko, Ito, Kyoko, Iwao, Takahiro, Ikeda, Akari, Hirose, Tomoyasu, Sunazuka, Toshiaki, Tanaka, Yasuhito, Matsunaga, Tamihide
Publicado 2022