Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and sulforaphane drug combination regimen

por SUTARIA, DHRUVITKUMAR, GRANDHI, BALAGANGADHAR KARTHIK, THAKKAR, ARVIND, WANG, JEFFREY, PRABHU, SUNIL
Publicado 2012

The molecular mechanism of action of aspirin, curcumin and sulforaphane combinations in the chemoprevention of pancreatic cancer

por THAKKAR, ARVIND, SUTARIA, DHRUVITKUMAR, GRANDHI, B. KARTHIK, WANG, JEFFREY, PRABHU, SUNIL
Publicado 2013

Drug–Drug Interaction Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Ipatasertib in Combination with Darolutamide in Patients with Advanced Prostate Cancer

por Sutaria, Dhruvitkumar S., Rasuo, Grozdana, Harris, Adam, Johnson, Ryan, Miles, Dale, Gallo, Jorge Daniel, Sane, Rucha
Publicado 2022

Pharmacokinetics of Ipatasertib in Subjects With Hepatic Impairment Using 2 Methods of Classification of Hepatic Function

por Sane, Rucha, Malhi, Vikram, Sutaria, Dhruvitkumar S, Cho, Eunpi, Twomey, Patrick, Craggs, Christopher, Wang, Jianshuang, Harris, Adam, Musib, Luna
Publicado 2021

Mitigating ipatasertib‐induced glucose increase through dose and meal timing modifications

por Sutaria, Dhruvitkumar S., Agarwal, Priya, Huang, Kuan‐Chieh, Miles, Dale R., Rotmensch, Jacob, Hinton, Heather, Gallo, Jorge Daniel, Rasuo, Grozdana, Sane, Rucha S.
Publicado 2022

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

por Bulitta, Jürgen B., Jiao, Yuanyuan, Landersdorfer, Cornelia B., Sutaria, Dhruvitkumar S., Tao, Xun, Shin, Eunjeong, Höhl, Rainer, Holzgrabe, Ulrike, Stephan, Ulrich, Sörgel, Fritz
Publicado 2019

Expression Profiling Identifies the Noncoding Processed Transcript of HNRNPU with Proliferative Properties in Pancreatic Ductal Adenocarcinoma

por Sutaria, Dhruvitkumar S., Jiang, Jinmai, Azevedo-Pouly, Ana Clara P., Lee, Eun Joo, Lerner, Megan R., Brackett, Daniel J., Vandesompele, Jo, Mestdagh, Pieter, Schmittgen, Thomas D.
Publicado 2017

Characterization of exposure–response relationships of ipatasertib in patients with metastatic castration-resistant prostate cancer in the IPATential150 study

por Kotani, Naoki, Wilkins, Justin J., Wade, Janet R., Dang, Steve, Sutaria, Dhruvitkumar S., Yoshida, Kenta, Sundrani, Sameer, Ding, Hao, Garcia, Josep, Hinton, Heather, Sane, Rucha, Chanu, Pascal
Publicado 2022

Novel Population Pharmacokinetic Approach to Explain the Differences between Cystic Fibrosis Patients and Healthy Volunteers via Protein Binding

por Shah, Nirav R., Bulitta, Jürgen B., Kinzig, Martina, Landersdorfer, Cornelia B., Jiao, Yuanyuan, Sutaria, Dhruvitkumar S., Tao, Xun, Höhl, Rainer, Holzgrabe, Ulrike, Kees, Frieder, Stephan, Ulrich, Sörgel, Fritz
Publicado 2019

CD44 positive and sorafenib insensitive hepatocellular carcinomas respond to the ATP-competitive mTOR inhibitor INK128

por Badawi, Mohamed, Kim, Jihye, Dauki, Anees, Sutaria, Dhruvitkumar, Motiwala, Tasneem, Reyes, Ryan, Wani, Nissar, Kolli, Shamalatha, Jiang, Jinmai, Coss, Christopher C., Jacob, Samson T., Phelps, Mitch A., Schmittgen, Thomas D.
Publicado 2018

Loss of RE-1 silencing transcription factor accelerates exocrine damage from pancreatic injury

por Bray, Julie K., Elgamal, Ola A., Jiang, Jinmai, Wright, Lais S., Sutaria, Dhruvitkumar S., Badawi, Mohamed, Borcyk, Madeline G., Liu, Xiuli, Fredenburg, Kristianna M., Campbell-Thompson, Martha L., Schmittgen, Thomas D.
Publicado 2020

Comprehensive toxicity and immunogenicity studies reveal minimal effects in mice following sustained dosing of extracellular vesicles derived from HEK293T cells

por Zhu, Xiaohua, Badawi, Mohamed, Pomeroy, Steven, Sutaria, Dhruvitkumar S., Xie, Zhiliang, Baek, Alice, Jiang, Jinmai, Elgamal, Ola A., Mo, Xiaokui, Perle, Krista La, Chalmers, Jeffrey, Schmittgen, Thomas D., Phelps, Mitch A.
Publicado 2017

Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery

por Sutaria, Dhruvitkumar S., Jiang, Jinmai, Elgamal, Ola A., Pomeroy, Steven M., Badawi, Mohamed, Zhu, Xiaohua, Pavlovicz, Ryan, Azevedo-Pouly, Ana Clara P., Chalmers, Jeffrey, Li, Chenglong, Phelps, Mitch A., Schmittgen, Thomas D.
Publicado 2017

Knockout of Acinar Enriched microRNAs in Mice Promote Duct Formation But Not Pancreatic Cancer

por Sutaria, Dhruvitkumar S., Jiang, Jinmai, Azevedo-Pouly, Ana Clara, Wright, Lais, Bray, Julie A., Fredenburg, Kristianna, Liu, Xiuli, Lu, Jun, Torres, Carolina, Mancinelli, Georgina, Grippo, Paul J., Coppola, Vincenzo, Schmittgen, Thomas D.
Publicado 2019

Globally increased ultraconserved noncoding RNA expression in pancreatic adenocarcinoma

por Jiang, Jinmai, Azevedo-Pouly, Ana Clara P., Redis, Roxana S., Lee, Eun Joo, Gusev, Yuriy, Allard, David, Sutaria, Dhruvitkumar S., Badawi, Mohamed, Elgamal, Ola A., Lerner, Megan R., Brackett, Daniel J., Calin, George A., Schmittgen, Thomas D.
Publicado 2016

Novel Cassette Assay To Quantify the Outer Membrane Permeability of Five β-Lactams Simultaneously in Carbapenem-Resistant Klebsiella pneumoniae and Enterobacter cloacae

por Kim, Tae Hwan, Tao, Xun, Moya, Bartolome, Jiao, Yuanyuan, Basso, Kari B., Zhou, Jieqiang, Lang, Yinzhi, Sutaria, Dhruvitkumar S., Zavascki, Alexandre P., Barth, Afonso L., Reeve, Stephanie M., Schweizer, Herbert P., Deveson Lucas, Deanna, Boyce, John D., Bonomo, Robert A., Lee, Richard E., Shin, Beom Soo, Louie, Arnold, Drusano, George L., Bulitta, Jürgen B.
Publicado 2020