Editorial: Death Receptors, Non-apoptotic Signaling Pathways and Inflammation

por Szegezdi, Eva, Legembre, Patrick
Publicado 2020

TRAIL in the Treatment of Cancer: From Soluble Cytokine to Nanosystems

por Alizadeh Zeinabad, Hojjat, Szegezdi, Eva
Publicado 2022

CCPlotR: an R package for the visualization of cell–cell interactions

por Ennis, Sarah, Ó Broin, Pilib, Szegezdi, Eva
Publicado 2023

An added dimension to tumour TRAIL sensitivity

por Healy, Sandra, O'Leary, Lynda, Szegezdi, Eva
Publicado 2015

The mitochondrial death pathway: a promising therapeutic target in diseases

por Gupta, Sanjeev, Kass, George EN, Szegezdi, Eva, Joseph, Bertrand
Publicado 2009

The BH3-mimetic ABT-737 effectively kills acute myeloid leukemia initiating cells

por Baev, Denis V., Krawczyk, Janusz, O׳Dwyer, Michael, Szegezdi, Eva
Publicado 2014

The Janus Face of Death Receptor Signaling during Tumor Immunoediting

por O’ Reilly, Eimear, Tirincsi, Andrea, Logue, Susan E., Szegezdi, Eva
Publicado 2016

Mechanisms of ER Stress-Mediated Mitochondrial Membrane Permeabilization

por Gupta, Sanjeev, Cuffe, Lorraine, Szegezdi, Eva, Logue, Susan E., Neary, Catherine, Healy, Sandra, Samali, Afshin
Publicado 2010

The Proteasome Inhibitor Bortezomib Sensitizes AML with Myelomonocytic Differentiation to TRAIL Mediated Apoptosis

por van Dijk, Marianne, Murphy, Eoin, Morrell, Ruth, Knapper, Steven, O'Dwyer, Michael, Samali, Afshin, Szegezdi, Eva
Publicado 2011

Aspartic Aminopeptidase Is a Novel Biomarker of Aggressive Chronic Lymphocytic Leukemia

por Kakodkar, Pramath, More, Sanket, András, Kinga, Papakonstantinou, Nikos, Kelly, Sharon, Makrooni, Mohammad Adib, Ortutay, Csaba, Szegezdi, Eva
Publicado 2020

Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xL

por Reeve, Janice LV, Szegezdi, Eva, Logue, Susan E, Chonghaile, Tríona Ní, O’Brien, Timothy, Ritter, Thomas, Samali, Afshin
Publicado 2007

Co-acting gene networks predict TRAIL responsiveness of tumour cells with high accuracy

por O’Reilly, Paul, Ortutay, Csaba, Gernon, Grainne, O’Connell, Enda, Seoighe, Cathal, Boyce, Susan, Serrano, Luis, Szegezdi, Eva
Publicado 2014

Stem cells are resistant to TRAIL receptor-mediated apoptosis

por Szegezdi, Eva, O’Reilly, Aoife, Davy, Yeung, Vawda, Reaz, Taylor, Deanna L, Murphy, Mary, Samali, Afshin, Mehmet, Huseyin
Publicado 2009

TRAIL promotes the polarization of human macrophages toward a proinflammatory M1 phenotype and is associated with increased survival in cancer patients with high tumor macrophage c...

por Gunalp, Sinem, Helvaci, Derya Goksu, Oner, Aysenur, Bursalı, Ahmet, Conforte, Alessandra, Güner, Hüseyin, Karakülah, Gökhan, Szegezdi, Eva, Sag, Duygu
Publicado 2023

The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL-induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia c...

por NATHWANI, SEEMA-MARIA, GREENE, LISA M., BUTINI, STEFANIA, CAMPIANI, GIUSEPPE, WILLIAMS, D. CLIVE, SAMALI, AFSHIN, SZEGEZDI, EVA, ZISTERER, DANIELA M.
Publicado 2016

Recreating the Bone Marrow Microenvironment to Model Leukemic Stem Cell Quiescence

por O’Reilly, Eimear, Zeinabad, Hojjat Alizadeh, Nolan, Caoimhe, Sefy, Jamileh, Williams, Thomas, Tarunina, Marina, Hernandez, Diana, Choo, Yen, Szegezdi, Eva
Publicado 2021

Cell-cell interactome of the hematopoietic niche and its changes in acute myeloid leukemia

por Ennis, Sarah, Conforte, Alessandra, O’Reilly, Eimear, Takanlu, Javid Sabour, Cichocka, Tatiana, Dhami, Sukhraj Pal, Nicholson, Pamela, Krebs, Philippe, Ó Broin, Pilib, Szegezdi, Eva
Publicado 2023

Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML

por O’ Reilly, Eimear, Dhami, Sukhraj Pal S., Baev, Denis V., Ortutay, Csaba, Halpin-McCormick, Anna, Morrell, Ruth, Santocanale, Corrado, Samali, Afshin, Quinn, John, O’Dwyer, Michael E, Szegezdi, Eva
Publicado 2018

Kinetics in Signal Transduction Pathways Involving Promiscuous Oligomerizing Receptors Can Be Determined by Receptor Specificity: Apoptosis Induction by TRAIL

por Szegezdi, Eva, van der Sloot, Almer M., Mahalingam, Devalingam, O'Leary, Lynda, Cool, Robbert H., Muñoz, Inés G., Montoya, Guillermo, Quax, Wim J., de Jong, Steven, Samali, Afshin, Serrano, Luis
Publicado 2012

Targeting AML through DR4 with a novel variant of rhTRAIL

por Szegezdi, Eva, Reis, Carlos R, van der Sloot, Almer M, Natoni, Alessandro, O’Reilly, Aoife, Reeve, Janice, Cool, Robbert H, O’Dwyer, Michael, Knapper, Steven, Serrano, Luis, Quax, Wim J, Samali, Afshin
Publicado 2011