Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells

por Li, Yongxin, Meng, Yu, Zhu, Xiangyang, Saadiq, Ishran M., Jordan, Kyra L., Eirin, Alfonso, Lerman, Lilach O.
Publicado 2020

Correction to: Metabolic syndrome increases senescence-associated micro-RNAs in extracellular vesicles derived from swine and human mesenchymal stem/stromal cells

por Li, Yongxin, Meng, Yu, Zhu, Xiangyang, Saadiq, Ishran M., Jordan, Kyra L., Eirin, Alfonso, Lerman, Lilach O.
Publicado 2020

Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

por Eirin, Alfonso, Ferguson, Christopher M., Zhu, Xiang-Yang, Saadiq, Ishran M., Tang, Hui, Lerman, Amir, Lerman, Lilach O.
Publicado 2020

Comparable in vitro Function of Human Liver-Derived and Adipose Tissue-Derived Mesenchymal Stromal Cells: Implications for Cell-Based Therapy

por Yigitbilek, Furkan, Conley, Sabena M., Tang, Hui, Saadiq, Ishran M., Jordan, Kyra L., Lerman, Lilach O., Taner, Timucin
Publicado 2021

Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles Elicit Better Preservation of the Intra-Renal Microvasculature Than Renal Revascularization in Pigs with Renovascular D...

por Ferguson, Christopher M., Farahani, Rahele A., Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Lerman, Amir, Lerman, Lilach O., Eirin, Alfonso
Publicado 2021

IL-10 partly mediates the ability of MSC-derived extracellular vesicles to attenuate myocardial damage in experimental metabolic renovascular hypertension

por Jiang, Yamei, Hong, Siting, Zhu, Xiangyang, Zhang, Lei, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Huang, Weijun, Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O.
Publicado 2022

The Micro-RNA Cargo of Extracellular Vesicles Released by Human Adipose Tissue-Derived Mesenchymal Stem Cells Is Modified by Obesity

por Eirin, Alfonso, Meng, Yu, Zhu, Xiang-Yang, Li, Yongxin, Saadiq, Ishran M., Jordan, Kyra L., Tang, Hui, Lerman, Amir, van Wijnen, Andre J., Lerman, Lilach O.
Publicado 2021

Effects of Elamipretide on Autophagy in Renal Cells of Pigs with Metabolic Syndrome

por Hong, Siting, Ghandriz, Ramyar, Siddiqi, Sarosh, Zhu, Xiang-Yang, Saadiq, Ishran M., Jordan, Kyra L., Tang, Hui, Ali, Khaled A., Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O.
Publicado 2022

Obesity Blunts the Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles

por Huang, Weijun, Hong, Siting, Zhu, Xiangyang, Alsaeedi, Mina H., Tang, Hui, Krier, James D., Gandhi, Deep, Jordan, Kyra L., Saadiq, Ishran M., Jiang, Yamei, Eirin, Alfonso, Lerman, Lilach O.
Publicado 2023

Low-Energy Shockwave Treatment Promotes Endothelial Progenitor Cell Homing to the Stenotic Pig Kidney

por Zhao, Yu, Santelli, Adrian, Zhu, Xiang-Yang, Zhang, Xin, Woollard, John R., Chen, Xiao-Jun, Jordan, Kyra L., Krier, James, Tang, Hui, Saadiq, Ishran, Lerman, Amir, Lerman, Lilach O.
Publicado 2020

Renal Ischemia Induces Epigenetic Changes in Apoptotic, Proteolytic, and Mitochondrial Genes in Swine Scattered Tubular-like Cells

por Rajagopalan, Kamalnath S., Glasstetter, Logan M., Zhu, Xiang-Yang, Thaler, Roman, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Herrmann, Sandra M., Chade, Alejandro R., Irazabal, Maria V., Lerman, Lilach O., Eirin, Alfonso
Publicado 2022

Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis- and senescence-related genes in swine adipose-derived mesenc...

por Glasstetter, Logan M., Oderinde, Tomiwa S., Mirchandani, Mohit, Rajagopalan, Kamalnath Sankaran, Barsom, Samer H., Thaler, Roman, Siddiqi, Sarosh, Zhu, Xiang-Yang, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., van Wijnen, Andre J., Eirin, Alfonso, Lerman, Lilach O.
Publicado 2023

Human Obesity Induces Dysfunction and Early Senescence in Adipose Tissue-Derived Mesenchymal Stromal/Stem Cells

por Conley, Sabena M., Hickson, LaTonya J., Kellogg, Todd A., McKenzie, Travis, Heimbach, Julie K., Taner, Timucin, Tang, Hui, Jordan, Kyra L., Saadiq, Ishran M., Woollard, John R., Isik, Busra, Afarideh, Mohsen, Tchkonia, Tamar, Kirkland, James L., Lerman, Lilach O.
Publicado 2020

Hypoxic preconditioning induces epigenetic changes and modifies swine mesenchymal stem cell angiogenesis and senescence in experimental atherosclerotic renal artery stenosis

por Isik, Busra, Thaler, Roman, Goksu, Busra B., Conley, Sabena M., Al-Khafaji, Hayder, Mohan, Arjunmohan, Afarideh, Mohsen, Abumoawad, Abdelrhman M., Zhu, Xiang Y., Krier, James D., Saadiq, Ishran M., Tang, Hui, Eirin, Alfonso, Hickson, LaTonya J., van Wijnen, Andre J., Textor, Stephen C., Lerman, Lilach O., Herrmann, Sandra M.
Publicado 2021

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

por Hickson, LaTonya J., Langhi Prata, Larissa G.P., Bobart, Shane A., Evans, Tamara K., Giorgadze, Nino, Hashmi, Shahrukh K., Herrmann, Sandra M., Jensen, Michael D., Jia, Qingyi, Jordan, Kyra L., Kellogg, Todd A., Khosla, Sundeep, Koerber, Daniel M., Lagnado, Anthony B., Lawson, Donna K., LeBrasseur, Nathan K., Lerman, Lilach O., McDonald, Kathleen M., McKenzie, Travis J., Passos, João F., Pignolo, Robert J., Pirtskhalava, Tamar, Saadiq, Ishran M., Schaefer, Kalli K., Textor, Stephen C., Victorelli, Stella G., Volkman, Tammie L., Xue, Ailing, Wentworth, Mark A., Wissler Gerdes, Erin O., Zhu, Yi, Tchkonia, Tamara, Kirkland, James L.
Publicado 2019

Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBi...

por Hickson, LaTonya J., Langhi Prata, Larissa G.P., Bobart, Shane A., Evans, Tamara K., Giorgadze, Nino, Hashmi, Shahrukh K., Herrmann, Sandra M., Jensen, Michael D., Jia, Qingyi, Jordan, Kyra L., Kellogg, Todd A., Khosla, Sundeep, Koerber, Daniel M., Lagnado, Anthony B., Lawson, Donna K., LeBrasseur, Nathan K., Lerman, Lilach O., McDonald, Kathleen M., McKenzie, Travis J., Passos, João F., Pignolo, Robert J., Pirtskhalava, Tamar, Saadiq, Ishran M., Schaefer, Kalli K., Textor, Stephen C., Victorelli, Stella G., Volkman, Tammie L., Xue, Ailing, Wentworth, Mark A., Wissler Gerdes, Erin O., Allison, David B., Dickinson, Stephanie L., Ejima, Keisuke, Atkinson, Elizabeth J., Lenburg, Marc, Zhu, Yi, Tchkonia, Tamara, Kirkland, James L.
Publicado 2020