Development of FRET‐based high‐throughput screening for viral RNase III inhibitors

por Wang, Linping, Saarela, Jani, Poque, Sylvain, Valkonen, Jari P.T.
Publicado 2020

The patatin-like lipase family in Gallus gallus

por Saarela, Jani, Jung, Gerlinde, Hermann, Marcela, Nimpf, Johannes, Schneider, Wolfgang J
Publicado 2008

Combined gene essentiality scoring improves the prediction of cancer dependency maps

por Wang, Wenyu, Malyutina, Alina, Pessia, Alberto, Saarela, Jani, Heckman, Caroline A., Tang, Jing
Publicado 2019

Corrigendum to ‘Combined gene essentiality scoring improves the prediction of cancer dependency maps’ [EBioMedicine 50 (2019) 66–79]

por Wang, Wenyu, Malyutina, Alina, Pessia, Alberto, Saarela, Jani, Heckman, Caroline A., Tang, Jing
Publicado 2020

In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III

por Wang, Linping, Poque, Sylvain, Laamanen, Karoliina, Saarela, Jani, Poso, Antti, Laitinen, Tuomo, Valkonen, Jari P. T.
Publicado 2021

Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1) – distinct characteristics in neurons

por Lyly, Annina, von Schantz, Carina, Salonen, Tarja, Kopra, Outi, Saarela, Jani, Jauhiainen, Matti, Kyttälä, Aija, Jalanko, Anu
Publicado 2007

Genome-wide siRNA screening reveals several host receptors for the binding of human gut commensal Bifidobacterium bifidum

por Kainulainen, Veera, von Schantz-Fant, Carina, Kovanen, Ruusu-Maria, Potdar, Swapnil, Laamanen, Karoliina, Saarela, Jani, Satokari, Reetta
Publicado 2022

BRCA1-deficient breast cancer cell lines are resistant to MEK inhibitors and show distinct sensitivities to 6-thioguanine

por Gu, Yuexi, Helenius, Mikko, Väänänen, Kristiina, Bulanova, Daria, Saarela, Jani, Sokolenko, Anna, Martens, John, Imyanitov, Evgeny, Kuznetsov, Sergey
Publicado 2016

Discovery of MINC1, a GTPase-Activating Protein Small Molecule Inhibitor, Targeting MgcRacGAP

por van Adrichem, Arjan J., Fagerholm, Annika, Turunen, Laura, Lehto, Anna, Saarela, Jani, Koskinen, Ari, Repasky, Gretchen A., Wennerberg, Krister
Publicado 2015

Breeze 2.0: an interactive web-tool for visual analysis and comparison of drug response data

por Potdar, Swapnil, Ianevski, Filipp, Ianevski, Aleksandr, Tanoli, Ziaurrehman, Wennerberg, Krister, Seashore-Ludlow, Brinton, Kallioniemi, Olli, Östling, Päivi, Aittokallio, Tero, Saarela, Jani
Publicado 2023

Breeze: an integrated quality control and data analysis application for high-throughput drug screening

por Potdar, Swapnil, Ianevski, Aleksandr, Mpindi, John-Patrick, Bychkov, Dmitrii, Fiere, Clément, Ianevski, Philipp, Yadav, Bhagwan, Wennerberg, Krister, Aittokallio, Tero, Kallioniemi, Olli, Saarela, Jani, Östling, Päivi
Publicado 2020

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

por Tuomainen, Katja, Hyytiäinen, Aini, Al-Samadi, Ahmed, Ianevski, Philipp, Ianevski, Aleksandr, Potdar, Swapnil, Turunen, Laura, Saarela, Jani, Kuznetsov, Sergey, Wahbi, Wafa, Risteli, Maija, Mäkitie, Antti, Monni, Outi, Salo, Tuula
Publicado 2021

High NRF2 Levels Correlate with Poor Prognosis in Colorectal Cancer Patients and with Sensitivity to the Kinase Inhibitor AT9283 In Vitro

por Torrente, Laura, Maan, Gunjit, Oumkaltoum Rezig, Asma, Quinn, Jean, Jackson, Angus, Grilli, Andrea, Casares, Laura, Zhang, Ying, Kulesskiy, Evgeny, Saarela, Jani, Bicciato, Silvio, Edwards, Joanne, Dinkova-Kostova, Albena T., de la Vega, Laureano
Publicado 2020

Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer

por Tang, Jing, Gautam, Prson, Gupta, Abhishekh, He, Liye, Timonen, Sanna, Akimov, Yevhen, Wang, Wenyu, Szwajda, Agnieszka, Jaiswal, Alok, Turei, Denes, Yadav, Bhagwan, Kankainen, Matti, Saarela, Jani, Saez-Rodriguez, Julio, Wennerberg, Krister, Aittokallio, Tero
Publicado 2019

High miR-30 Expression Associates with Improved Breast Cancer Patient Survival and Treatment Outcome

por Jamshidi, Maral, Fagerholm, Rainer, Muranen, Taru A., Kaur, Sippy, Potdar, Swapnil, Khan, Sofia, Netti, Eliisa, Mpindi, John-Patrick, Yadav, Bhagwan, Kiiski, Johanna I., Aittomäki, Kristiina, Heikkilä, Päivi, Saarela, Jani, Bützow, Ralf, Blomqvist, Carl, Nevanlinna, Heli
Publicado 2021

Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments

por Tanoli, Ziaurrehman, Aldahdooh, Jehad, Alam, Farhan, Wang, Yinyin, Seemab, Umair, Fratelli, Maddalena, Pavlis, Petr, Hajduch, Marian, Bietrix, Florence, Gribbon, Philip, Zaliani, Andrea, Hall, Matthew D., Shen, Min, Brimacombe, Kyle, Kulesskiy, Evgeny, Saarela, Jani, Wennerberg, Krister, Vähä-Koskela, Markus, Tang, Jing
Publicado 2021

Minimal information for chemosensitivity assays (MICHA): a next-generation pipeline to enable the FAIRification of drug screening experiments

por Tanoli, Ziaurrehman, Aldahdooh, Jehad, Alam, Farhan, Wang, Yinyin, Seemab, Umair, Fratelli, Maddalena, Pavlis, Petr, Hajduch, Marian, Bietrix, Florence, Gribbon, Philip, Zaliani, Andrea, Hall, Matthew D, Shen, Min, Brimacombe, Kyle, Kulesskiy, Evgeny, Saarela, Jani, Wennerberg, Krister, Vähä-Koskela, Markus, Tang, Jing
Publicado 2021

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

por Malani, Disha, Kumar, Ashwini, Brück, Oscar, Kontro, Mika, Yadav, Bhagwan, Hellesøy, Monica, Kuusanmäki, Heikki, Dufva, Olli, Kankainen, Matti, Eldfors, Samuli, Potdar, Swapnil, Saarela, Jani, Turunen, Laura, Parsons, Alun, Västrik, Imre, Kivinen, Katja, Saarela, Janna, Räty, Riikka, Lehto, Minna, Wolf, Maija, Gjertsen, Bjorn Tore, Mustjoki, Satu, Aittokallio, Tero, Wennerberg, Krister, Heckman, Caroline A., Kallioniemi, Olli, Porkka, Kimmo
Publicado 2022

Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins

por Bulanova, Daria, Ianevski, Aleksandr, Bugai, Andrii, Akimov, Yevhen, Kuivanen, Suvi, Paavilainen, Henrik, Kakkola, Laura, Nandania, Jatin, Turunen, Laura, Ohman, Tiina, Ala-Hongisto, Hanna, Pesonen, Hanna M., Kuisma, Marika S., Honkimaa, Anni, Walton, Emma L., Oksenych, Valentyn, Lorey, Martina B., Guschin, Dmitry, Shim, Jungmin, Kim, Jinhee, Than, Thoa T., Chang, So Young, Hukkanen, Veijo, Kulesskiy, Evgeny, Marjomaki, Varpu S., Julkunen, Ilkka, Nyman, Tuula A., Matikainen, Sampsa, Saarela, Jani S., Sane, Famara, Hober, Didier, Gabriel, Gülsah, De Brabander, Jef K., Martikainen, Miika, Windisch, Marc P., Min, Ji-Young, Bruzzone, Roberto, Aittokallio, Tero, Vähä-Koskela, Markus, Vapalahti, Olli, Pulk, Arto, Velagapudi, Vidya, Kainov, Denis E.
Publicado 2017

OTHR-04. DEVELOPMENT OF A FUNCTIONAL PLATFORM FOR REAL-TIME PERSONALIZED DRUG SENSITIVITY PROFILING OF PATIENT-DERIVED 3D FRESH TUMOR TISSUE CULTURES IN THE PEDIATRIC PRECISION ONC...

por Peterziel, Heike, Jamaladdin, Nora, ElHarouni, Dina, Gerloff, Xenia F, Herter, Sonja, Fiesel, Petra, Berker, Yannick, Blattner-Johnson, Mirjam, Schramm, Kathrin, Jones, Barbara C, Reuss, David, Turunen, Laura, Friedenauer, Aileen, Holland-Letz, Tim, Sill, Martin, Weiser, Lena, Previti, Christopher, Balasubramanian, Gnanaprakash, Gerber, Nicolas U, Gojo, Johannes, Hutter, Caroline, Øra, Ingrid, Lohi, Olli, Kattamis, Antonis, de Wilde, Bram, Westermann, Frank, Tippelt, Stephan, Graf, Norbert, Nathrath, Michaela, Sparber-Sauer, Monika, Sehested, Astrid, Kramm, Christof M, Dirksen, Uta, Kallioniemi, Olli, Pfister, Stefan M, van Tilburg, Cornelis M, Jones, David T W, Saarela, Jani, Pietiäinen, Vilja, Jäger, Natalie, Schlesner, Matthias, Kopp-Schneider, Annette, Oppermann, Sina, Milde, Till, Witt, Olaf, Oehme, Ina
Publicado 2023