Neurotrophic factors for disease-modifying treatments of Parkinson's disease: gaps between basic science and clinical studies

por Chmielarz, Piotr, Saarma, Mart
Publicado 2020

Neurotrophic Factors in Parkinson’s Disease: Clinical Trials, Open Challenges and Nanoparticle-Mediated Delivery to the Brain

por Bondarenko, Olesja, Saarma, Mart
Publicado 2021

Endoplasmic Reticulum Stress Regulators: New Drug Targets for Parkinson’s Disease

por Kovaleva, Vera, Saarma, Mart
Publicado 2021

Cerebral dopamine neurotrophic factor protects and repairs dopamine neurons by novel mechanism

por Lindholm, Päivi, Saarma, Mart
Publicado 2021

CDNF Protein Therapy in Parkinson’s Disease

por Huttunen, Henri J., Saarma, Mart
Publicado 2019

Small Molecules and Peptides Targeting Glial Cell Line-Derived Neurotrophic Factor Receptors for the Treatment of Neurodegeneration

por Sidorova, Yulia A., Saarma, Mart
Publicado 2020

The role of SorLA in neurotrophic activity and complex behavior

por Glerup, Simon, Saarma, Mart, Nykjaer, Anders
Publicado 2013

Protection of dopamine neurons by CDNF and neurturin variant N4 against MPP(+) in dissociated cultures from rat mesencephalon

por Jaumotte, Juliann D., Saarma, Mart, Zigmond, Michael J.
Publicado 2021

CDNF and MANF regulate ER stress in a tissue-specific manner

por Pakarinen, Emmi, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria
Publicado 2022

In vivo screening reveals interactions between Drosophila Manf and genes involved in the mitochondria and the ubiquinone synthesis pathway

por Lindström, Riitta, Lindholm, Päivi, Palgi, Mari, Saarma, Mart, Heino, Tapio I.
Publicado 2017

Small-Molecule Ligands as Potential GDNF Family Receptor Agonists

por Ivanova, Larisa, Tammiku-Taul, Jaana, Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Publicado 2018

Characterization of Drosophila GDNF Receptor-Like and Evidence for Its Evolutionarily Conserved Interaction with Neural Cell Adhesion Molecule (NCAM)/FasII

por Kallijärvi, Jukka, Stratoulias, Vassilis, Virtanen, Kristel, Hietakangas, Ville, Heino, Tapio I., Saarma, Mart
Publicado 2012

Exploring the Conserved Role of MANF in the Unfolded Protein Response in Drosophila melanogaster

por Lindström, Riitta, Lindholm, Päivi, Kallijärvi, Jukka, Palgi, Mari, Saarma, Mart, Heino, Tapio I.
Publicado 2016

c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s Disease

por Lindholm, Dan, Pham, Dan D., Cascone, Annunziata, Eriksson, Ove, Wennerberg, Krister, Saarma, Mart
Publicado 2016

MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex

por Tseng, Kuan-Yin, Danilova, Tatiana, Domanskyi, Andrii, Saarma, Mart, Lindahl, Maria, Airavaara, Mikko
Publicado 2017

Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

por Galli, Emilia, Lindholm, Päivi, Kontturi, Leena-Stiina, Saarma, Mart, Urtti, Arto, Yliperttula, Marjo
Publicado 2019

Increased Serum Levels of Mesencephalic Astrocyte-Derived Neurotrophic Factor in Subjects With Parkinson’s Disease

por Galli, Emilia, Planken, Anu, Kadastik-Eerme, Liis, Saarma, Mart, Taba, Pille, Lindholm, Päivi
Publicado 2019

A deep convolutional neural network approach for astrocyte detection

por Suleymanova, Ilida, Balassa, Tamas, Tripathi, Sushil, Molnar, Csaba, Saarma, Mart, Sidorova, Yulia, Horvath, Peter
Publicado 2018

Molecular Dynamics Simulations of the Interactions between Glial Cell Line-Derived Neurotrophic Factor Family Receptor GFRα1 and Small-Molecule Ligands

por Ivanova, Larisa, Tammiku-Taul, Jaana, García-Sosa, Alfonso T., Sidorova, Yulia, Saarma, Mart, Karelson, Mati
Publicado 2018

Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Is Highly Expressed in Mouse Tissues With Metabolic Function

por Danilova, Tatiana, Galli, Emilia, Pakarinen, Emmi, Palm, Erik, Lindholm, Päivi, Saarma, Mart, Lindahl, Maria
Publicado 2019