Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities

por Kar, Bibekananda, Castillo, Santiago R., Sabharwal, Ankit, Clark, Karl J., Ekker, Stephen C.
Publicado 2023

An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines

por Kar, Bibekananda, Sabharwal, Ankit, Restrepo-Castillo, Santiago, Simone, Brandon W., Clark, Karl J., Ekker, Stephen C.
Publicado 2022

Chamber Specific Gene Expression Landscape of the Zebrafish Heart

por Singh, Angom Ramcharan, Sivadas, Ambily, Sabharwal, Ankit, Vellarikal, Shamsudheen Karuthedath, Jayarajan, Rijith, Verma, Ankit, Kapoor, Shruti, Joshi, Adita, Scaria, Vinod, Sivasubbu, Sridhar
Publicado 2016

The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells In Vitro and Zebrafish Disease Models In Vivo

por Sabharwal, Ankit, Kar, Bibekananda, Restrepo-Castillo, Santiago, Holmberg, Shannon R., Mathew, Neal D., Kendall, Benjamin Luke, Cotter, Ryan P., WareJoncas, Zachary, Seiler, Christoph, Nakamaru-Ogiso, Eiko, Clark, Karl J., Ekker, Stephen C.
Publicado 2021

A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish

por Sabharwal, Ankit, Campbell, Jarryd M., Schwab, Tanya L., WareJoncas, Zachary, Wishman, Mark D., Ata, Hirotaka, Liu, Wiebin, Ichino, Noriko, Hunter, Danielle E., Bergren, Jake D., Urban, Mark D., Urban, Rhianna M., Holmberg, Shannon R., Kar, Bibekananda, Cook, Alex, Ding, Yonghe, Xu, Xiaolei, Clark, Karl J., Ekker, Stephen C.
Publicado 2022

Genetic therapy in a mitochondrial disease model suggests a critical role for liver dysfunction in mortality

por Sabharwal, Ankit, Wishman, Mark D, Cervera, Roberto Lopez, Serres, MaKayla R, Anderson, Jennifer L, Holmberg, Shannon R, Kar, Bibekananda, Treichel, Anthony J, Ichino, Noriko, Liu, Weibin, Yang, Jingchun, Ding, Yonghe, Deng, Yun, Lacey, Jean M, Laxen, William J, Loken, Perry R, Oglesbee, Devin, Farber, Steven A, Clark, Karl J, Xu, Xiaolei, Ekker, Stephen C
Publicado 2022

Building the vertebrate codex using the gene breaking protein trap library

por Ichino, Noriko, Serres, MaKayla R, Urban, Rhianna M, Urban, Mark D, Treichel, Anthony J, Schaefbauer, Kyle J, Tallant, Lauren E, Varshney, Gaurav K, Skuster, Kimberly J, McNulty, Melissa S, Daby, Camden L, Wang, Ying, Liao, Hsin-kai, El-Rass, Suzan, Ding, Yonghe, Liu, Weibin, Anderson, Jennifer L, Wishman, Mark D, Sabharwal, Ankit, Schimmenti, Lisa A, Sivasubbu, Sridhar, Balciunas, Darius, Hammerschmidt, Matthias, Farber, Steven Arthur, Wen, Xiao-Yan, Xu, Xiaolei, McGrail, Maura, Essner, Jeffrey J, Burgess, Shawn M, Clark, Karl J, Ekker, Stephen C
Publicado 2020

The Zebrafish GenomeWiki: a crowdsourcing approach to connect the long tail for zebrafish gene annotation

por Singh, Meghna, Bhartiya, Deeksha, Maini, Jayant, Sharma, Meenakshi, Singh, Angom Ramcharan, Kadarkaraisamy, Subburaj, Rana, Rajiv, Sabharwal, Ankit, Nanda, Srishti, Ramachandran, Aravindhakshan, Mittal, Ashish, Kapoor, Shruti, Sehgal, Paras, Asad, Zainab, Kaushik, Kriti, Vellarikkal, Shamsudheen Karuthedath, Jagga, Divya, Muthuswami, Muthulakshmi, Chauhan, Rajendra K., Leonard, Elvin, Priyadarshini, Ruby, Halimani, Mahantappa, Malhotra, Sunny, Patowary, Ashok, Vishwakarma, Harinder, Joshi, Prateek, Bhardwaj, Vivek, Bhaumik, Arijit, Bhatt, Bharat, Jha, Aamod, Kumar, Aalok, Budakoti, Prerna, Lalwani, Mukesh Kumar, Meli, Rajeshwari, Jalali, Saakshi, Joshi, Kandarp, Pal, Koustav, Dhiman, Heena, Laddha, Saurabh V., Jadhav, Vaibhav, Singh, Naresh, Pandey, Vikas, Sachidanandan, Chetana, Ekker, Stephen C., Klee, Eric W., Scaria, Vinod, Sivasubbu, Sridhar
Publicado 2014