The siRNA sequence and guide strand overhangs are determinants of in vivo duration of silencing

por Strapps, Walter R., Pickering, Victoria, Muiru, Gladys T., Rice, Julie, Orsborn, Stacey, Polisky, Barry A., Sachs, Alan, Bartz, Steven R.
Publicado 2010

ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5)

por Ason, Brandon, Castro-Perez, Jose, Tep, Samnang, Stefanni, Alice, Tadin-Strapps, Marija, Roddy, Thomas, Hankemeier, Thomas, Hubbard, Brian, Sachs, Alan B., Michael Flanagan, W., Kuklin, Nelly A., Mitnaul, Lyndon J.
Publicado 2011

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo

por Kenski, Denise M., Cooper, Abby J., Li, Jenny J., Willingham, Aarron T., Haringsma, Henry J., Young, Tracy A., Kuklin, Nelly A., Jones, Jeffrey J., Cancilla, Mark T., McMasters, Daniel R., Mathur, Melina, Sachs, Alan B., Flanagan, W. Michael
Publicado 2010

High Resolution Discovery Proteomics Reveals Candidate Disease Progression Markers of Alzheimer’s Disease in Human Cerebrospinal Fluid

por Hendrickson, Ronald C., Lee, Anita Y. H., Song, Qinghua, Liaw, Andy, Wiener, Matt, Paweletz, Cloud P., Seeburger, Jeffrey L., Li, Jenny, Meng, Fanyu, Deyanova, Ekaterina G., Mazur, Matthew T., Settlage, Robert E., Zhao, Xuemei, Southwick, Katie, Du, Yi, Holder, Dan, Sachs, Jeffrey R., Laterza, Omar F., Dallob, Aimee, Chappell, Derek L., Snyder, Karen, Modur, Vijay, King, Elizabeth, Joachim, Catharine, Bondarenko, Andrey Y., Shearman, Mark, Soper, Keith A., Smith, A. David, Potter, William Z., Koblan, Ken S., Sachs, Alan B., Yates, Nathan A.
Publicado 2015